Search

Your search keyword '"swept source OCT"' showing total 2 results
Start Over Descriptor "swept source OCT" Journal international medical case reports journal
2 results on '"swept source OCT"'

1. Segmented swept source optical coherence tomography angiography assessment of the perifoveal vasculature in patients with X-linked juvenile retinoschisis: a serial case report.

Author

Stringa, Francesco, Tsamis, Emmanouli, Papayannis, Alessandro, Chwiejczak, Katarzyna, Jalil, Assad, Biswas, Susmito, Ahmad, Hassan, and Stanga, Paulo Eduardo

Subjects
EYE diseases, OPTICAL coherence tomography, ANGIOGRAPHY, MEDICAL quality control, PATIENTS
Abstract

Purpose: To describe perifoveal microvascular changes occurring in X-linked juvenile retinoschisis (XLRS) using swept source optical coherence tomography angiography (SS OCTA). Patients and methods: This is a serial case report of three patients. Retrospective data of patients affected by XLRS were collected. Structural optical coherence tomography (OCT) and color fundus photography (CFPh) were carried out with Topcon® OCT 2000 3D OCT as part of the standard care. Two patients were imaged on Topcon Atlantis® SS OCTA and one on Topcon Triton® SS OCTA. SS OCTA images were acquired using the 3x 3 mm fovea-centered cubes scanning protocol. Analysis of both perifoveal superficial vascular plexus (pSVP) and perifoveal deep vascular plexus (pDVP) was performed by two observers after automated segmentation. Results: Four eyes of three males (mean age 14 ± 3.8 years) were analyzed. All eyes showed foveoschisis on CFPh images. OCT B-scans of three eyes showed schistic cysts in the ganglion cell layer, inner nuclear layer (INL) and outer nuclear layer (ONL); in one eye, cysts were depicted in INL and ONL only. In two eyes, SS OCTA showed abnormal foveal avascular zone (FAZ) shape in the pSVP and in the other two, FAZ shape was abnormal in both plexuses. In all eyes, retinal vascular abnormalities (ie, microvascular protrusions) were present in pDVP. Conclusion: SS OCTA can depict perifoveal microvascular changes in young patients affected by XLRS. In this study, the structural and vascular changes seem to be more evident in the pDVP and may represent a useful biomarker of prognosis. [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
View/download PDF

2. Segmented swept source optical coherence tomography angiography assessment of the perifoveal vasculature in patients with X-linked juvenile retinoschisis: a serial case report

Author

Paulo E. Stanga, Hassan Ahmad, Assad Jalil, Alessandro Papayannis, Susmito Biswas, Francesco Stringa, Katarzyna Chwiejczak, and Emmanouli Tsamis

Subjects
medicine.medical_specialty, retina, genetic structures, 030204 cardiovascular system & hematology, Foveoschisis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Optical coherence tomography, swept source OCT, Ophthalmology, medicine, Case Series, Outer nuclear layer, Ganglion cell layer, Retina, medicine.diagnostic_test, business.industry, OCT angiography, Retinal, General Medicine, Optical coherence tomography angiography, pediatric ophthalmology, eye diseases, 3. Good health, medicine.anatomical_structure, chemistry, Inner nuclear layer, 030221 ophthalmology & optometry, International Medical Case Reports Journal, Radiology, sense organs, business, X-linked retinoschisis
Abstract

Francesco Stringa,1,2 Emmanouli Tsamis,1,3 Alessandro Papayannis,1 Katarzyna Chwiejczak,1 Assad Jalil,2 Susmito Biswas,1,2,4 Hassan Ahmad,1 Paulo Eduardo Stanga1,2,4 1Manchester Vision Regeneration (MVR) at NIHR/Wellcome Trust Manchester Clinical Research Facility, 2Manchester Royal Eye Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, 3Division of Pharmacy and Optometry, School of Health Sciences, 4Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester,UK Purpose: To describe perifoveal microvascular changes occurring in X-linked juvenile retinoschisis (XLRS) using swept source optical coherence tomography angiography (SS OCTA).Patients and methods: This is a serial case report of three patients. Retrospective data of patients affected by XLRS were collected. Structural optical coherence tomography (OCT) and color fundus photography (CFPh) were carried out with Topcon® OCT 2000 3D OCT as part of the standard care. Two patients were imaged on Topcon Atlantis® SS OCTA and one on Topcon Triton® SS OCTA. SS OCTA images were acquired using the 3 × 3 mm fovea-centered cubes scanning protocol. Analysis of both perifoveal superficial vascular plexus (pSVP) and perifoveal deep vascular plexus (pDVP) was performed by two observers after automated segmentation.Results: Four eyes of three males (mean age 14 ± 3.8 years) were analyzed. All eyes showed foveoschisis on CFPh images. OCT B-scans of three eyes showed schistic cysts in the ganglion cell layer, inner nuclear layer (INL) and outer nuclear layer (ONL); in one eye, cysts were depicted in INL and ONL only. In two eyes, SS OCTA showed abnormal foveal avascular zone (FAZ) shape in the pSVP, and in the other two, FAZ shape was abnormal in both plexuses. In all eyes, retinal vascular abnormalities (ie, microvascular protrusions) were present in pDVP.Conclusion: SS OCTA can depict perifoveal microvascular changes in young patients affected by XLRS. In this study, the structural and vascular changes seem to be more evident in the pDVP and may represent a useful biomarker of prognosis. Keywords: retina, pediatric ophthalmology, swept source OCT, OCT angiography, X-linked retinoschisis

Published
2017

Catalog

Books, media, physical & digital resources
See catalog results