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Start Over Author "Milone, Marco" Journal international journal of surgery
9 results on '"Milone, Marco"'

8. Clinical outcome in differentiated thyroid carcinoma and microcarcinoma

Author

Fiammetta Romano, Nunzia Verde, Livia Barba, Marco Milone, Giovanni Lupoli, Gelsy Arianna Lupoli, Maria Vastarella, Roberta Lupoli, Marianna Cacciapuoti, Anna Tortora, Francesco Fonderico, Stefania Masone, Lupoli, Roberta, Cacciapuoti, Marianna, Tortora, Anna, Barba, Livia, Verde, N, Romano, F, Vastarella, M, Fonderico, F, Masone, S, Milone, Marco, Lupoli, Giovanni, and Lupoli, Gelsy

Subjects
Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Iodine Radioisotopes, Thyroid carcinoma, Lesion, Differentiated Thyroid carcinoma, Recurrence, Risk Factors, medicine, Humans, Thyroid Neoplasms, Lymph node, Aged, business.industry, Incidence (epidemiology), Thyroid, Thyroidectomy, Lymphadenectomy, General Medicine, Middle Aged, Prognosis, Tumor Burden, Surgery, Dissection, medicine.anatomical_structure, Female, Radiotherapy, Adjuvant, thyroid microcarcinoma, Radiology, Neoplasm Recurrence, Local, Radiopharmaceuticals, medicine.symptom, business, Follow-Up Studies
Abstract

INTRODUCTION: Due to the frequent use of neck ultrasonography, the incidence of differentiated thyroid microcarcinoma (DTMC), defined as a lesion with greatest dimension ≤1 cm, is increasing worldwide. Although DTMC generally has a lower aggressivity and a better prognosis than differentiated thyroid carcinoma (DTC), some cases of clinically aggressive DTMC were found. The aim of this study is to compare the rate of recurrence in DTMC and DTC, during a 3-year follow-up. METHODS: Patients with differentiated thyroid carcinoma, who underwent total thyroidectomy and postoperative (131)I-RAI ablation, were stratified according to lesion diameter (DTC for diameter > 1 cm or DTMC ≤ 1 cm). After surgery, patients underwent a 3-year follow-up. Recurrent disease was defined on the basis of positive biochemical (Tg > 2 ng/ml under TSH-suppression or after rhTSH-stimulation) and/or imaging (US, WBS, CT, PET/CT) findings. RESULTS: 449 patients have been included in the final analysis. Linfoadenectomy rate and RAI ablative dose were significantly higher in DTC than in DTMC (32.7% vs. 22.4%, p = 0.018 and 112.3 ± 21 vs. 68.3 ± 24.1 mCi, p < 0.001). During the follow-up, 50 carcinoma recurrences occurred, more frequent in DTC than in DTMC (15.6% vs. 7.6%, p = 0.010). After adjustment for gender, age, rate of lymph node dissection and 131I dose of RAI treatment, the difference in the risk of recurrence was no longer significant among DTC and DTMC patients (HR: 1.585, 95% CI 0874-2877, p = 0.130). CONCLUSIONS: The prediction of disease severity cannot be based exclusively on lesion diameter. A more careful therapeutic approach and follow-up should be recommended in DTMC patients.

Published
2014

9. Bariatric surgery in elderly patients. A comparison between gastric banding and sleeve gastrectomy with five years of follow up

Author

Dario Gaudioso, Paola Maietta, Anna Pisapia, Paolo Bianco, Francesco Milone, Guido Coretti, Mario Musella, Marco Milone, Musella, Mario, Milone, Marco, Paola, Maietta, Paolo, Bianco, Guido, Coretti, Anna, Pisapia, Dario, Gaudioso, and Milone, Francesco

Subjects
Male, medicine.medical_specialty, Sleeve gastrectomy, Gastroplasty, medicine.medical_treatment, Cost-Benefit Analysis, Population, Morbid obesity, Quality of life, Weight loss, Gastrectomy, Weight Loss, medicine, Humans, Postoperative Period, education, Aged, Retrospective Studies, Bariatric surgery, education.field_of_study, business.industry, General Medicine, Length of Stay, medicine.disease, Obesity, Pulmonary embolism, Surgery, Obesity, Morbid, Elderly patients, Treatment Outcome, Laparoscopic gastric banding, Quality of Life, Female, Laparoscopy, medicine.symptom, business, Laparoscopic adjustable gastric banding, Body mass index, Elderly patient, Follow-Up Studies
Abstract

Introduction: The prevalence of obesity is rising progressively, even among elderly patients. Many studies investigated about safety and efficacy of bariatric surgery among aged obese patients. The objective of this review is to assess the benefits relative to risks of weight loss that may be obtained by performing two common bariatric procedures in obese elderly patient. Materials and methods: We retrospectively evaluated 10 morbid obese patients older than 60 years reaching 5 years of follow up who respectively underwent Laparoscopic Sleeve Gastrectomy (LSG) or Laparoscopic Adjustable Gastric Banding (LAGB). Eventual changes in comorbidities, weight loss, EWL% were investigated. Results: Although LSG patients required a longer postoperative hospital stay than LAGB patients (p

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