1. Work disability in Argentinian patients with systemic lupus erythematosus is prevalent and it is due to ethnic, socioeconomic and disease-related factors.
- Author
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Pisoni CN, Muñoz SA, Tamborenea MN, García M, Curti A, Cappuccio A, Rillo O, Imamura PM, Schneeberger E, Ballent M, Cousseau ML, Velasco Zamora J, Saurit V, Toloza S, Danielsen MC, Bellomio VI, Graf C, Paira S, Cavallasca J, Pons Estel B, Moreno JLC, Díaz M, Alba P, Verando M, Tate G, Mysler E, Sarano J, Civit EE, Risueño F, Álvarez Sepúlveda P, Larroude MS, Méndez MF, Conforti A, and Sohn D
- Subjects
- Adult, Argentina epidemiology, Cross-Sectional Studies, Emotions, Female, Health Status, Humans, Lupus Erythematosus, Systemic diagnosis, Lupus Erythematosus, Systemic psychology, Lupus Erythematosus, Systemic therapy, Male, Mental Health, Middle Aged, Poverty, Prevalence, Quality of Life, Risk Factors, Sedentary Behavior, Young Adult, Absenteeism, Disability Evaluation, Indians, South American, Lupus Erythematosus, Systemic ethnology, Sick Leave, Social Determinants of Health, Socioeconomic Factors
- Abstract
Objective: To study the prevalence and the associated factors of work disability (WD) in systemic lupus erythematosus (SLE) patients., Methods: A sample of 419 SLE patients from an observational cross-sectional multicenter study was included. Sociodemographic features, disease characteristics, comorbidities, quality of life, unhealthy behaviors, and work-related factors were measured in a standardized interview. Work disability was defined by patient self-report of not being able to work because of SLE. To identify variables associated with work disability, two different multivariate regression models using a stepwise backward method were performed., Results: Prevalence of WD due to SLE was 24.3%. Eighty-nine percent were female and 51% were Caucasians. Mean disease duration was 8.9 ± 7.2 years, and median System Lupus International Collaborating Clinics/American College of Rheumatology damage index SLICC-SDI was 1.5 (range 0-17). In stepwise multivariate logistic regression, living below the poverty line (odds ratio [OR] = 4.65), less than 12 years of education (OR = 2.84), Mestizo ethnicity (OR = 1.94) and SLICC-SDI (OR = 1.25) were predictors of WD. A second model was performed including patient-derived measures; in this model sedentary lifestyle (OR = 2.69) and lower emotional health domain score of the Lupus Quality of Life (LupusQoL) questionnaire (OR = 1.03) were found to be associated to WD and a higher score in LupusQoL physical health domain (OR = 0.93) was protective., Conclusion: The prevalence of WD in Argentinian SLE patients was 24.3%. WD was associated with ethnic (Mestizo), socioeconomic (poverty) and disease-related factors. Patient-related outcomes such us sedentary lifestyle and poor emotional quality of life were also associated with WD., (© 2018 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.)
- Published
- 2018
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