1. Comparative study of hematological parameters along with effect of chemotherapy and radiotherapy in different stages of breast cancer
- Author
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Sanjay Singh Chandel, Reetika Shrivastava, Swati Shrivastava, Akshay Nigam, Sarvesh Kumar, and Neelima Singh
- Subjects
Oncology ,Chemotherapy ,medicine.medical_specialty ,Pathology ,business.industry ,medicine.medical_treatment ,Healthy subjects ,medicine.disease ,Radiation therapy ,Breast cancer ,Hematology analyzer ,Internal medicine ,medicine ,business - Abstract
Background: Breast cancer is one of the most common malignancies found among women in India. Haematological parameters have been shown to predict severity, mortality and treatment follow-up in breast cancer patients. The aim of the study was to compare haematological parameters along with effect of chemotherapy and radiotherapy in different stages of breast cancer patients.Methods: Total 235 human subjects were taken in the study. Out of which 100 normal ages matched healthy subjects were considered as controls and 135 breast cancer patients subjects as cases which were further divided into their respective stages according to TNM classification.Results: Estimation of haematological parameters was done by Sysmex Automated Hematology Analyzer Kx-21. The statistical differences between cases and control were determined by using student independent sample t-test.Conclusions: We found hemoglobin level, polymorphs, lymphocytes, monocytes and RBC count were statistically reduce (p
- Published
- 2016
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