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Start Over Author "Sun K" Journal international journal of radiation oncology, biology, physics
30 results on '"Sun K"'

26. Postoperative Radiation Therapy in Pathologic T2-3N0M0 Thoracic Esophageal Squamous Cell Carcinoma: Interim Report of a Prospective, Phase 3, Randomized Controlled Study

Author

Deng, W., Yang, J., Xiao, Z., Wang, X., Zhou, Z., Zhang, H., Chen, D., Feng, Q., Liang, J., Lv, J., Zhang, T., Bi, N., Wang, W., Deng, L., Hui, Z., Wang, L., He, J., Gao, S., Xue, Q., Mao, Y., Sun, K., Liu, X., Fang, D., Li, J., Wang, D., Mou, J., Zhao, J., Li, Z., Lei, W., Wang, Y., and Chen, X.

Published
2017
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27. Validating the RTOG-endorsed brachial plexus contouring atlas: an evaluation of reproducibility among patients treated by intensity-modulated radiotherapy for head-and-neck cancer

Author

Allen M. Chen, Vishal Gupta, Mathew Mathai, William H. Hall, James A. Purdy, Sun K. Yi, and Arthur B. Dublin

Subjects
Organs at Risk, Cancer Research, Radiography, medicine.medical_treatment, Medical illustration, Medical Illustration, Medicine, Humans, Radiology, Nuclear Medicine and imaging, Brachial Plexus, Radiation treatment planning, Brachial Plexus Neuropathies, Observer Variation, Reproducibility, Contouring, Radiation, business.industry, Radiotherapy Planning, Computer-Assisted, Head and neck cancer, Reproducibility of Results, Radiotherapy Dosage, medicine.disease, Radiation therapy, Oncology, Head and Neck Neoplasms, Radiotherapy, Intensity-Modulated, business, Nuclear medicine, Brachial plexus
Abstract

Purpose To evaluate interobserver variability for contouring the brachial plexus as an organ-at-risk (OAR) and to analyze its potential dosimetric consequences in patients treated with intensity-modulated radiotherapy (IMRT) for head-and-neck cancer. Methods and Materials Using the Radiation Therapy Oncology Group (RTOG)-endorsed brachial plexus contouring atlas, three radiation oncologists independently delineated the OAR on treatment planning computed-tomography (CT) axial scans from 5 representative patients undergoing IMRT to a prescribed dose of 70 Gy for head-and-neck cancer. Dose-volume histograms for the brachial plexus were calculated, and interobserver differences were quantified by comparing various dosimetric statistics. Qualitative analysis was performed by visually assessing the overlapping contours on a single beam’s eye view. Results Brachial plexus volumes for the 5 patients across observers were 26 cc (18–35 cc), 25 cc (21–30 cc), 29 cc (28–32 cc), 29 cc (23–38 cc), and 29 cc (23–34 cc). On qualitative analysis, minimal variability existed except at the inferolateral portion of the OAR, where slight discrepancies were noted among the physicians. Maximum doses to the brachial plexus ranged from 71.6 to 72.6 Gy, 75.2 to 75.8 Gy, 69.1 to 71.0 Gy, 76.4 to 76.9 Gy, and 70.6 to 71.4 Gy. Respective volumes receiving doses greater than 60 Gy (V60) were 8.6 to 10.9 cc, 6.2 to 8.1 cc, 8.2 to 11.6 cc, 8.3 to 10.5 cc, and 5.6 to 9.8 cc. Conclusion The RTOG-endorsed brachial plexus atlas provides a consistent set of guidelines for contouring this OAR with essentially no learning curve. Adoption of these contouring guidelines in the clinical setting is encouraged.

Published
2010

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