1. Opportunistic Community Screening of Chronic Chagas Disease Using a Rapid Diagnosis Test in Pharmacies in Barcelona (Catalonia, Spain): Study Protocol and Pilot Phase Results
- Author
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Aroa Silgado, Pau Bosch-Nicolau, Adrián Sánchez-Montalvá, Ariadna Cervià, Jordi Gomez-i-Prat, Guillermo Bagaria, Cristina Rodriguez, Lidia Goterris, Núria Serre-Delcor, Inés Oliveira-Souto, Fernando Salvador, Israel Molina, Elena Sulleiro, Institut Català de la Salut, [Silgado A, Goterris L] Servei de Microbiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. PROSICS Barcelona, Spain. [Bosch-Nicolau P, Sánchez-Montalvá A, Serre-Delcor N, Oliveira-Souto I, Salvador F, Molina I] Servei de Malalties Infeccioses, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. PROSICS Barcelona, Spain. Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain. [Cervià A, Bagaria G, Rodriguez C] Official College of Pharmacists of Barcelona, Barcelona, Spain. [Gomez-I-Prat J] Servei de Malalties Infeccioses, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. PROSICS Barcelona, Spain. [Sulleiro E] Servei de Microbiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. PROSICS Barcelona, Spain. Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain, and Vall d'Hebron Barcelona Hospital Campus
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Pharmacies ,Health (social science) ,Chagas, Malaltia de - Diagnòstic ,Otros calificadores::/diagnóstico [Otros calificadores] ,Public Health, Environmental and Occupational Health ,Hispanic or Latino ,Diagnosis::Diagnostic Techniques and Procedures::Mass Screening [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT] ,Farmàcies ,enfermedades parasitarias::infecciones por protozoos::infecciones por Euglenozoa::tripanosomiasis::enfermedad de Chagas [ENFERMEDADES] ,Health Care Facilities, Manpower, and Services::Health Facilities::Pharmacies [HEALTH CARE] ,Spain ,Cribatge (Medicina) ,Other subheadings::/diagnosis [Other subheadings] ,diagnóstico::técnicas y procedimientos diagnósticos::cribado sistemático [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS] ,Humans ,Mass Screening ,instalaciones, servicios y personal de asistencia sanitaria::centros sanitarios::farmacias [ATENCIÓN DE SALUD] ,Chagas Disease ,Parasitic Diseases::Protozoan Infections::Euglenozoa Infections::Trypanosomiasis::Chagas Disease [DISEASES] - Abstract
Chagas disease; Community pharmacies; Rapid test Enfermedad de Chagas; Farmacias comunitarias; Test rapido Malaltia de Chagas; Farmàcies comunitàries; Prova ràpida Objectives: This study aimed to report the protocol and results from the pilot phase of an opportunistic CP-based CD screening program in Barcelona, Spain. Methods: Three strategies according to recruitment approach were designed: passive, active and active-community. The study process consisted of signing the informed consent form, recording the patient’s data in a web-based database system, and performing the rapid test and blood collection on dry paper. Results: Nineteen pharmacies participated and 64 patients were included during the pilot phase of the study. The rapid diagnostic test (RDT) was positive in 2/64 (3.13%) cases. Of the 49 DBS samples that arrived at the laboratory, 22 (45%) were collected incorrectly. After quantitative and qualitative assessment of the program, the dry paper sample and passive strategy were ruled out. Conclusion: DBS sampling and the passive strategy are not suitable for CD screening in community pharmacies. There is a need to expand the number of participating pharmacies and individuals to determine whether conducting a RDT in community pharmacies is an effective screening method to increase access to CD diagnosis in a non-endemic area. This work has been supported by the Fundació la Marató TV3 (project number 481/U/2018).
- Published
- 2022