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Your search keyword '"VELIS, DEMETRIOS"' showing total 6 results
Start Over Author "VELIS, DEMETRIOS" Journal international journal of neural systems
6 results on '"VELIS, DEMETRIOS"'

6. REACTIVE CONTROL OF EPILEPTIFORM DISCHARGES IN REALISTIC COMPUTATIONAL NEURONAL MODELS WITH BISTABILITY.

Author

KOPPERT, MARC, KALITZIN, STILIYAN, VELIS, DEMETRIOS, DA SILVA, FERNANDO LOPES, and VIERGEVER, MAX A.

Subjects
COMPUTATIONAL neuroscience, MOLECULAR dynamics, SPASMS, BRAIN stimulation, PARAMETER estimation, DEGREES of freedom, REAL-time control
Abstract

We aim to derive fully autonomous seizure suppression paradigms based on reactive control of neuronal dynamics. A previously derived computational model of seizure generation describing collective degrees of freedom and featuring bistable dynamics is used. A novel technique for real-time control of epileptogenicity is introduced. The reactive control reduces practically all seizures in the model. The study indicates which parameters provide the maximal seizure reduction with minimal intervention. An adaptive scheme is proposed that optimizes the stimulation parameters in nonstationary situations. [ABSTRACT FROM AUTHOR]

Published
2013
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