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Start Over Author "Bintou Fane" Journal international journal of mycobacteriology
2 results on '"Bintou Fane"'

1. Competitive fitness of Mycobacterium tuberculosis in vitro

Author

Ousmane Kodio, Antieme Combo Georges Togo, Yeya dit Sadio Sarro, Bintou Fane, Fatimata Diallo, Amadou Somboro, Boureima Degoga, Mahamadou Kone, Gagni Coulibaly, Mohamed Tolofoudje, Sidy Bane, Moumine Sanogo, Bourahima Kone, Nadie Coulibaly, Djeneba Dabitao, Bocar Baya, Mamoudou Maiga, Flabou Bougoudogo, Fasse Samake, Sounkalo Dao, Seydou Doumbia, Souleymane Diallo, and Bassirou Diarra

Subjects
cost of resistance, in vitro competition, mali, mycobacterium tuberculosis-multidrug-resistant, Microbiology, QR1-502
Abstract

Background: While, bacteria resistance mutations can affect competitive fitness, given our multidrug-resistant (MDR) prevalence, we conducted this study to determine the impact of MDR on the competitive fitness of Mycobacterium tuberculosis (MTB) complex MDR strains. We conducted a cross-sectional study at the University Clinical Research Center (UCRC) from January to December 2017. New TB patients over aged of 18 were recruited at University teaching hospital and health reference centers of Bamako in USTTB Ethical committee approved protocols. Methods: MDR and drug-susceptible (wild-type [WT]) MTB strains (T1 and Beijing) and MTB H37Rv were competed on solid media in UCRC's Tuberculosis Laboratory. Competitive and individual cultures were incubated for 14 days at 37°C with 7% CO2. Number of generation, generation time, and relative competitive fitness (W) of the strains were calculated. Data were analyzed with Epi-Info 7.1.5.2 software (CDC). P value was considered significant when it was

Published
2019
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2. Competitive Fitness of Mycobacterium tuberculosis in vitro

Author

Mohamed Tolofoudje, Bocar Baya, Yeya dit Sadio Sarro, Sidy Bane, Bourahima Kone, Souleymane Diallo, Ousmane Kodio, Djeneba Dabitao, Moumine Sanogo, Bintou Fane, Gagni Coulibaly, Mamoudou Maiga, Nadie Coulibaly, Boureima Degoga, Fasse Samake, Bassirou Diarra, Fatimata Diallo, Mahamadou Kone, Sounkalo Dao, Seydou Doumbia, F Bougoudogo, Amadou Somboro, and Antieme Combo Georges Togo

Subjects
0301 basic medicine, Microbiology (medical), Tuberculosis, Genotype, 030106 microbiology, lcsh:QR1-502, Antitubercular Agents, Mali, lcsh:Microbiology, Article, Mycobacterium tuberculosis, 03 medical and health sciences, Drug Resistance, Multiple, Bacterial, Tuberculosis, Multidrug-Resistant, medicine, Humans, Prospective Studies, biology, Competitive fitness, Mycobacterium tuberculosis-multidrug-resistant, biology.organism_classification, medicine.disease, Solid medium, Virology, In vitro, 3. Good health, 030104 developmental biology, Infectious Diseases, in vitro competition, Mutation, Cost of resistance, University teaching, Genetic Fitness
Abstract

Background: While, bacteria resistance mutations can affect competitive fitness, given our multidrug-resistant (MDR) prevalence, we conducted this study to determine the impact of MDR on the competitive fitness of Mycobacterium tuberculosis (MTB) complex MDR strains. We conducted a cross-sectional study at the University Clinical Research Center (UCRC) from January to December 2017. New TB patients over aged of 18 were recruited at University teaching hospital and health reference centers of Bamako in USTTB Ethical committee approved protocols. Methods: MDR and drug-susceptible (wild-type [WT]) MTB strains (T1 and Beijing) and MTB H37Rv were competed on solid media in UCRC's Tuberculosis Laboratory. Competitive and individual cultures were incubated for 14 days at 37°C with 7% CO2. Number of generation, generation time, and relative competitive fitness (W) of the strains were calculated. Data were analyzed with Epi-Info 7.1.5.2 software (CDC). P value was considered significant when it was

Published
2019

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