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Your search keyword '"Lavigne, Jean‐Philippe"' showing total 8 results
Start Over Author "Lavigne, Jean‐Philippe" Journal international journal of molecular sciences
8 results on '"Lavigne, Jean‐Philippe"'

3. Phenotypic and Genotypic Virulence Characterisation of Staphylococcus pettenkoferi Strains Isolated from Human Bloodstream and Diabetic Foot Infections

Author

Magnan, Chloé, primary, Ahmad-Mansour, Nour, additional, Pouget, Cassandra, additional, Morsli, Madjid, additional, Huc-Brandt, Sylvaine, additional, Pantel, Alix, additional, Dunyach-Remy, Catherine, additional, Sotto, Albert, additional, Molle, Virginie, additional, and Lavigne, Jean-Philippe, additional

Published
2022
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4. Characterization of the Secreted Acid Phosphatase SapS Reveals a Novel Virulence Factor of Staphylococcus aureus That Contributes to Survival and Virulence in Mice

Author

Ahmad-Mansour, Nour, primary, Elhawy, Mohamed Ibrahem, additional, Huc-Brandt, Sylvaine, additional, Youssouf, Nadhuma, additional, Pätzold, Linda, additional, Martin, Marianne, additional, Abdel-Wadood, Noran, additional, Aljohmani, Ahmad, additional, Morsli, Madjid, additional, Krasteva-Christ, Gabriela, additional, Becker, Sören L., additional, Yildiz, Daniela, additional, Lavigne, Jean-Philippe, additional, Gannoun-Zaki, Laila, additional, Bischoff, Markus, additional, and Molle, Virginie, additional

Published
2022
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8. Biofilm Formation by Staphylococcus aureus in the Specific Context of Cystic Fibrosis.

Author

Jean-Pierre, Vincent, Boudet, Agathe, Sorlin, Pauline, Menetrey, Quentin, Chiron, Raphaël, Lavigne, Jean-Philippe, and Marchandin, Hélène

Subjects
CYSTIC fibrosis, BACTERIAL colonies, BIOFILMS, STAPHYLOCOCCUS aureus, ACHROMOBACTER
Abstract

Staphylococcus aureus is a major human pathogen whose characteristics support its success in various clinical settings including Cystic Fibrosis (CF). In CF, S. aureus is indeed the most commonly identified opportunistic pathogen in children and the overall population. S. aureus colonization/infection, either by methicillin-susceptible or methicillin-resistant strains, will become chronic in about one third of CF patients. The persistence of S. aureus in CF patients' lungs, despite various eradication strategies, is favored by several traits in both host and pathogen. Among the latter, living in biofilm is a highly protective way to survive despite deleterious environmental conditions, and is a common characteristic shared by the main pathogens identified in CF. This is why CF has earned the status of a biofilm-associated disease for several years now. Biofilm formation by S. aureus, and the molecular mechanisms governing and regulating it, have been extensively studied but have received less attention in the specific context of CF lungs. Here, we review the current knowledge on S. aureus biofilm in this very context, i.e., the importance, study methods, molecular data published on mono- and multi-species biofilm and anti-biofilm strategies. This focus on studies including clinical isolates from CF patients shows that they are still under-represented in the literature compared with studies based on reference strains, and underlines the need for such studies. Indeed, CF clinical strains display specific characteristics that may not be extrapolated from results obtained on laboratory strains. [ABSTRACT FROM AUTHOR]

Published
2023
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