1. Prenatal and Neonatal Pulmonary Thrombosis as a Potential Complication of SARS-CoV-2 Infection in Late Pregnancy.
- Author
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Abdulaziz-Opiela, Gazala, Sobieraj, Anna, Sibrecht, Greta, Bajdor, Julia, Mroziński, Bartłomiej, Kozłowska, Zuzanna, Iciek, Rafał, Wróblewska-Seniuk, Katarzyna, Wender-Ożegowska, Ewa, and Szczapa, Tomasz
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MULTISYSTEM inflammatory syndrome in children , *MULTISYSTEM inflammatory syndrome , *LOW-molecular-weight heparin , *SARS-CoV-2 , *THROMBOSIS , *MULLERIAN ducts - Abstract
Neonatal venous thrombosis is a rare condition that can be iatrogenic or occur due to viral infections or genetic mutations. Thromboembolic complications are also commonly observed as a result of SARS-CoV-2 infections. They can affect pediatric patients, especially the ones suffering from multisystem inflammatory syndrome in children (MIS-C) or multisystem inflammatory syndrome in neonates (MIS-N). The question remains whether the maternal SARS-CoV-2 infection during pregnancy can lead to thromboembolic complications in fetuses and neonates. We report on a patient born with an embolism in the arterial duct, left pulmonary artery, and pulmonary trunk, who presented several characteristic features of MIS-N, suspecting that the cause might have been the maternal SARS-CoV2 infection in late pregnancy. Multiple genetic and laboratory tests were performed. The neonate presented only with a positive result of IgG antibodies against SARS-CoV-2. He was treated with low molecular weight heparin. Subsequent echocardiographic tests showed that the embolism dissolved. More research is necessary to evaluate the possible neonatal complications of maternal SARS-CoV-2 infection. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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