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Your search keyword '"Lax, Sigurd F."' showing total 9 results
Start Over Author "Lax, Sigurd F." Journal international journal of gynecological pathology
9 results on '"Lax, Sigurd F."'

2. Neuroendocrine Marker Expression in Primary Non-neuroendocrine Epithelial Tumors of the Ovary: A Study of 551 Cases.

Author

Bártů, Michaela Kendall, Němejcová, Kristýna, Michálková, Romana, Quang Hiep Bui, Drozenová, Jana, Fabian, Pavel, Fadare, Oluwole, Hausnerová, Jitka, Laco, Jan, Matěj, Radoslav, Méhes, Gábor, Šafanda, Adam, Singh, Naveena, Škapa, Petr, Špůrková, Zuzana, Stolnicu, Simona, Švajdler, Marián, Lax, Sigurd F., McCluggage, W. Glenn, and Dundr, Pavel

Published
2024
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3. Neuroendocrine Marker Expression in Primary Non-neuroendocrine Epithelial Tumors of the Ovary: A Study of 551 Cases

Author

Kendall Bártů, Michaela, Němejcová, Kristýna, Michálková, Romana, Bui, Quang Hiep, Drozenová, Jana, Fabian, Pavel, Fadare, Oluwole, Hausnerová, Jitka, Laco, Jan, Matěj, Radoslav, Méhes, Gábor, Šafanda, Adam, Singh, Naveena, Škapa, Petr, Špůrková, Zuzana, Stolnicu, Simona, Švajdler, Marián, Lax, Sigurd F., McCluggage, W. Glenn, and Dundr, Pavel

Abstract

Expression of neuroendocrine (NE) markers in primary ovarian non-NE epithelial tumors has rarely been evaluated. The aim of our study was to evaluate the expression of the most widely used NE markers in these neoplasms and to determine any prognostic significance of NE marker expression. The cohort consisted of 551 primary ovarian tumors, including serous borderline tumors, low-grade serous carcinomas, high-grade serous carcinomas (HGSC), clear cell carcinomas, endometroid carcinomas, mucinous borderline tumors, and mucinous carcinomas. Immunohistochemical analysis was performed using antibodies against INSM1, synaptophysin, chromogranin, and CD56 on tissue microarray. Positivity for INSM1, synaptophysin, chromogranin, and CD56 was most frequently observed in mucinous tumors (48.7%, 26.0%, 41.5%, and 100%, respectively). The positivity for these NE markers was mostly restricted to nonmucinous elements distributed throughout the tumor. The mucinous borderline tumor and mucinous carcinomas groups had similar proportions of positivity (mucinous borderline tumor: 53%, mucinous carcinomas: 39%). In the other tumor types, except for HGSC, there was only focal expression (5%–10%) or negativity for NE markers. HGSC showed high CD56 expression (in 26% of cases). Survival analysis was only performed for CD56 in HGSC as this was the only group with sufficient positive cases, and it showed no prognostic significance. Except for mucinous tumors, expression of NE markers in non-NE ovarian epithelial tumors is low. CD56 expression in HGSC occurs frequently but is without diagnostic or prognostic value.

Published
2024
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4. Data Set for the Reporting of Endometrial Cancer: Recommendations From the International Collaboration on Cancer Reporting (ICCR)

Author

Matias-Guiu, Xavier, primary, Selinger, Christina I., additional, Anderson, Lyndal, additional, Buza, Natalia, additional, Ellenson, Lora H., additional, Fadare, Oluwole, additional, Ganesan, Raji, additional, Ip, Philip P.C., additional, Palacios, Jose, additional, Parra-Herran, Carlos, additional, Raspollini, Maria R., additional, Soslow, Robert A., additional, Werner, Henrica M.J., additional, Lax, Sigurd F., additional, and McCluggage, W. Glenn, additional

Published
2022
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5. Dataset for the Reporting of Gestational Trophoblastic Neoplasia: Recommendations From the International Collaboration on Cancer Reporting (ICCR)

Author

Hui, Pei, primary, Webster, Fleur, additional, Baergen, Rebecca N., additional, Buza, Natalia, additional, Cheung, Annie N.Y., additional, Kaur, Baljeet, additional, Ronnett, Brigitte M., additional, Shih, Ie-Ming, additional, Seckl, Michael J., additional, Lax, Sigurd F., additional, and McCluggage, W. Glenn, additional

Published
2022
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6. Data Set for the Reporting of Ovarian, Fallopian Tube and Primary Peritoneal Carcinoma: Recommendations From the International Collaboration on Cancer Reporting (ICCR)

Author

Gilks, C. Blake, primary, Selinger, Christina I., additional, Davidson, Ben, additional, Köbel, Martin, additional, Ledermann, Jonathan A., additional, Lim, Diana, additional, Malpica, Anais, additional, Mikami, Yoshiki, additional, Singh, Naveena, additional, Srinivasan, Radhika, additional, Vang, Russell, additional, Lax, Sigurd F., additional, and McCluggage, W. Glenn, additional

Published
2022
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7. Data Set for the Reporting of Carcinomas of the Vulva: Recommendations From the International Collaboration on Cancer Reporting (ICCR)

Author

Hoang, Lynn, primary, Webster, Fleur, additional, Bosse, Tjalling, additional, Focchi, Gustavo, additional, Gilks, C. Blake, additional, Howitt, Brooke E., additional, McAlpine, Jessica N., additional, Ordi, Jaume, additional, Singh, Naveena, additional, Wong, Richard Wing-Cheuk, additional, Lax, Sigurd F., additional, and McCluggage, W. Glenn, additional

Published
2022
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8. Data Set for Reporting of Uterine Malignant and Potentially Malignant Mesenchymal Tumors: Recommendations From the International Collaboration on Cancer Reporting (ICCR)

Author

Nucci, Marisa R., primary, Webster, Fleur, additional, Croce, Sabrina, additional, George, Suzanne, additional, Howitt, Brooke E., additional, Ip, Philip P.C., additional, Lee, Cheng-Han, additional, Rabban, Joseph T., additional, Soslow, Robert A., additional, van der Griend, Rachael, additional, Lax, Sigurd F., additional, and McCluggage, W. Glenn, additional

Published
2022
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9. Dataset for the Reporting of Carcinoma of the Cervix: Recommendations From the International Collaboration on Cancer Reporting (ICCR)

Author

Park, Kay J., primary, Selinger, Christina I., additional, Alvarado-Cabrero, Isabel, additional, Duggan, Máire A., additional, Kiyokawa, Takako, additional, Mills, Anne M., additional, Ordi, Jaume, additional, Otis, Christopher N., additional, Plante, Marie, additional, Stolnicu, Simona, additional, Talia, Karen L., additional, Wiredu, Edwin K., additional, Lax, Sigurd F., additional, and McCluggage, W. Glenn, additional

Published
2022
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