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Start Over Author "Rosimeire S. Albuquerque" Journal international journal of food properties
1 results on '"Rosimeire S. Albuquerque"'

1. High-Performance Liquid Chromatography-Diodic Array Detector, Fungistatic, and Anti-Morphogenical Analysis of Extracts from Psidium brownianum Mart. ex DC. Against Yeasts of the Genus Candida

Author

Débora Lima Sales, Rosimeire S. Albuquerque, Aline Augusti Boligon, Antonio Judson Targino Machado, Dara Isabel Vieira de Brito, Felipe S. Ferreira, Joara Nályda Pereira Carneiro, Maria Flaviana Bezerra Morais-Braga, Edeltrudes de Oliveira Lima, João Tavares Calixto Júnior, Djair S.L. Souza, José Galberto Martins da Costa, Henrique Douglas Melo Coutinho, Irwin Rose Alencar de Menezes, and Margareth Linde Athayde

Subjects
0301 basic medicine, Psidium, Chromatography, Strain (chemistry), 030106 microbiology, Decoction, Biology, High-performance liquid chromatography, Genus Candida, Microbiology, Fungicide, 03 medical and health sciences, Minimum inhibitory concentration, 030104 developmental biology, IC50, Food Science
Abstract

We assessed extracts from Psidium brownianum for antifungal activity and identified the phenolic phytocompounds. Minimum inhibitory concentration was determined by microdilution and IC50 was calculated. The minimun fungicidal concentration and the morphology of Candida were evaluated. Extracts analyzed by high-performance liquid chromatography demonstrated flavonoids and phenolic acids. The minimum inhibitory concentration was 8192 µg/mL and the IC50 varied between 1056 and 5128 µg/mL. Extracts showed fungistatic effect and altered the dimorphism of the strains, being the better result observed using the decoction, that affected the fungal dimorphism of the strain CA ATCC40006 at 4096 µg/mL.

Published
2016
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