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Trauma-exposed adults with high levels of posttraumatic stress symptoms (PTSS) report poorer health-related quality of life (HRQOL), but less is known about the persistence of this relationship over time. Participants from the Vietnam Era Twin Study of Aging reported on PTSS, health, and sociodemographic characteristics at average age 38; 775 participants reported having been exposed to trauma. Later, at average ages 56 and 62, mental and physical HRQOL were assessed with the Short-Form 36. Premorbid risk for anxiety/neuroticism was evaluated with a polygenic risk score derived from a large genome-wide association study meta-analysis. In multivariate mixed models, having higher levels of PTSS, poorer self-rated health, lower income, and less education at age 38 were associated with worse physical and mental HRQOL two decades later. Chronic health problems at age 38 predicted midlife physical but not mental HRQOL. Although genetic risk for neuroticism was correlated with HRQOL and PTSS, it was no longer significant in multivariate models. Health-related quality of life (HRQOL) predicts morbidity and mortality independently of objective health measures; early interventions may help to mitigate the ongoing impact of trauma on quality of life.

Air pollution originating from road traffic is a known risk factor of respiratory and cardiovascular disease (both in terms of chronic and acute effects). While adverse effects on cardiovascular health have also been linked with noise (after controlling for air pollution), noise exposure has been commonly linked to sleep impairment and negative emotional reactions. Health is multi-faceted, both conceptually and operationally; Health-Related Quality of Life (HRQOL) is one of many measures capable of probing health. In this study, we examine pre-collected data from postal surveys probing HRQOL obtained from a variety of urban, suburban, and rural contexts across the North Island of New Zealand. Analyses focus on the covariance between air pollution annoyance and noise annoyances, and their independent and combined effects on HRQOL. Results indicate that the highest ratings of air pollution annoyance and noise annoyances were for residents living close to the motorway, while the lowest were for rural residents. Most of the city samples indicated no significant difference between air pollution- and noise-annoyance ratings, and of all of the correlations between air pollution- and noise-annoyance, the highest were found in the city samples. These findings suggest that annoyance is driven by exposure to environmental factors and not personality characteristics. Analysis of HRQOL indicated that air pollution annoyance predicts greater variability in the physical HRQOL domain while noise annoyance predicts greater variability in the psychological, social and environmental domains. The lack of an interaction effect between air pollution annoyance and noise annoyance suggests that air pollution and noise impact on health independently. These results echo those obtained from objective measures of health and suggest that mitigation of traffic effects should address both air and noise pollution.