Search

Your search keyword '"Cirilli, N."' showing total 2 results
Start Over Author "Cirilli, N." Journal international journal of environmental research and public health
2 results on '"Cirilli, N."'

1. The Italian External Quality Assessment Program for Cystic Fibrosis Sweat Chloride Test: Does Active Participation Improve the Quality?

Author

Valeria Raia, Giuseppe Castaldo, Natalia Cirilli, Ettore Capoluongo, Annalisa Amato, Marco Salvatore, Rita Padoan, Carlo Corbetta, Fabrizio Tosto, Domenica Taruscio, Giovanna Floridia, Ubaldo Caruso, Federica Censi, Gianluca Ferrari, Salvatore, M., Amato, A., Floridia, G., Censi, F., Ferrari, G., Tosto, F., Padoan, R., Raia, V., Cirilli, N., Castaldo, G., Capoluongo, E., Caruso, U., Corbetta, C., and Taruscio, D.

Subjects
sweat test, medicine.medical_specialty, Quality Assurance, Health Care, diagnosis, Health, Toxicology and Mutagenesis, media_common.quotation_subject, Sweat chloride, lcsh:Medicine, Cystic fibrosis, Article, cystic fibrosis, active participation, 03 medical and health sciences, 0302 clinical medicine, Chlorides, 030225 pediatrics, External quality assessment, medicine, Humans, Medical physics, Quality (business), Prospective Studies, 030212 general & internal medicine, Sweat, Sweat test, media_common, Accreditation, medicine.diagnostic_test, business.industry, lcsh:R, Public Health, Environmental and Occupational Health, choloride, external quality assessment, medicine.disease, Test (assessment), Active participation, Italy, quality, Cystic fibrosi, business, Diagnosi
Abstract

(1) Background: Diagnostic testing for cystic fibrosis (CF) is based on a sweat chloride test (SCT) considering the appropriate signs and symptoms of the disease and results of a gene mutation analysis. In 2014, the Istituto Superiore di Sanit&agrave, (ISS) established a pilot Italian external quality assessment program for CF SCT (Italian EQA-SCT), which is now a third party service carried out by the ISS. (2) Methods: The ongoing scheme is prospective, enrollment is voluntary, and the payment of a fee is required. Results are shared through a dedicated web-facility. Assessment covers the analysis, interpretation, and reporting of results. (3) Results: Thirteen, fifteen, sixteen, and fifteen different laboratories, respectively, participated from 2015 to 2016 and from 2018 to 2019 in the Italian EQA-SCT scheme. Eleven different laboratories participated each year in all four rounds of the Italian EQA-SCT. (4) Conclusions: The overall results obtained from the laboratories participating constantly clearly show that their qualitative and quantitative performance improved significantly. This is due to the opportunity&mdash, after receiving the EQA results&mdash, to constantly review their performance and address any inconsistencies. We firmly believe that participation in the EQA program will improve the quality of participating laboratories and that EQA participation should become mandatory as a fundamental requirement for laboratory accreditation.

Published
2020
Full Text
View/download PDF

2. Cystic Fibrosis Mortality in Childhood. Data from European Cystic Fibrosis Society Patient Registry.

Author

Zolin A, Bossi A, Cirilli N, Kashirskaya N, and Padoan R

Subjects
Adolescent, Child, Child, Preschool, Developed Countries, Developing Countries, Europe epidemiology, Female, Health Services Accessibility economics, Humans, Income statistics & numerical data, Infant, Logistic Models, Male, Risk Factors, Cystic Fibrosis mortality, Registries statistics & numerical data
Abstract

Data collected in the European Cystic Fibrosis Society Patient Registry (ECFSPR) database were used to investigate whether risk factors for death in childhood and adolescents CF patients have different impact in countries of different income. In this way, it is possible to recognize where interventions could improve the quality of care and survival in these patients. We matched deceased and alive patients by age, country, year of follow-up. Multivariable logistic models were developed. In the years of this study, the ECFSPR collected information on 24,416 patients younger than 18 years: 7830 patients were from countries with low/middle income and 16,586 from countries with high income; among these the dead are 102 and 107 ( p < 0.001), respectively. The use of oxygen, forced expiratory volume in one second (FEV₁) below 40% and BMI standard deviation score (SDS) below -2 represent risk factors for death. However, some patients from countries with high income remain alive even if their values of FEV₁% and BMI-SDS were low, and some deceased patients from countries with high income had high values of FEV₁% (>60%). Evaluation of mortality in pediatric age may reflect the availability of resources for CF diagnosis and treatment in some countries.

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results