1. Differences of Mohs micrographic surgery in basal cell carcinoma versus squamous cell carcinoma
- Author
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Matias Mayor Arenal, Pedro Redondo, Cristina Ciudad-Blanco, Raquel Navarro Tejedor, Marãa L. Alonso Pacheco, J.R. Garcés, Ricardo Suarez Fernández, Eva Vilarrasa, L. Hueso, Victoriano Morales-Gordillo, Izascun Ocerin-Guerra, Maria J. Seoane‐Pose, O. Sanmartín-Jiménez, Ignacio García-Doval, José L. López-Estebaranz, Esther de Eusebio Murillo, Roman Miñano Medrano, Natividad Cano-Martinez, Lucia Barchino, T. Alonso-Alonso, Juan L. Artola Igarza, Alberto Alfaro Rubio, Hugo Vázquez-Veiga, Manuel Ángel Rodríguez-Prieto, Miguel Ángel Descalzo, Irati Allende Markixana, Yolanda Delgado Jiménez, Agustí Toll, Pablo de la Cueva Dobao, Celia Camarero‐Mulas, and Veronica Ruiz-Salas
- Subjects
Adult ,Male ,medicine.medical_specialty ,Neoplasm, Residual ,Skin Neoplasms ,medicine.medical_treatment ,Operative Time ,Dermatology ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Postoperative Complications ,Carcinoma ,medicine ,Humans ,Basal cell carcinoma ,Basal cell ,Neoplasm Invasiveness ,Prospective Studies ,Young adult ,Prospective cohort study ,neoplasms ,Aged ,Aged, 80 and over ,business.industry ,Incidence (epidemiology) ,fungi ,Age Factors ,Margins of Excision ,Immunosuppression ,Perioperative ,Middle Aged ,medicine.disease ,Mohs Surgery ,Surgery ,Tumor Burden ,stomatognathic diseases ,Carcinoma, Basal Cell ,030220 oncology & carcinogenesis ,Carcinoma, Squamous Cell ,Female ,Neoplasm Recurrence, Local ,business - Abstract
BackgroundThe two main tumors treated with Mohs micrographic surgery (MMS) are basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). There are no studies analyzing whether MMS is different when treating these two types of tumors. ObjectiveWe aim to compare the characteristics of the patients, the tumors, and MMS, and first-year follow-up of MMS in BCC and SCC. MethodsREGESMOHS is a prospective cohort study of patients treated with MMS. The participating centers are 19 Spanish hospitals where at least one MMS is performed per week. Data on characteristics of the patients, tumors, and surgery were recorded. The follow-up was done with two visits: the first visit within 1 month after surgery and the second one within the first year. ResultsFrom July 2013 to April 2017, a total of 2,669 patients who underwent MMS were included in the registry. Of them, 2,448 (93%) were diagnosed with BCC, and 181 (7%) were diagnosed with SCC. Patients with SCC were older than those with BCC (median age 73 years vs. 68 years) and presented immunosuppression more frequently. The tumor size was significantly larger in the SCC group. Regarding surgery, deeper invasion was more frequent in SCC, resulting in larger defects. Despite this, SCC did not require more stages to get clear margins or more time in the operating room. Incomplete Mohs was more frequent in the SCC group (6%) than in the BCC group (2%). The incidence of perioperative complications was higher when treating SCC. There were more relapses in the first-year follow-up in the SCC group. ConclusionThere are significant differences when comparing MMS in BCC and SCC. Knowledge of these differences can help to prepare the patient and plan the surgery, optimizing results.
- Published
- 2018