4 results on '"Van Gils, C.H."'
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2. Variety in vegetable and fruit consumption and risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition
- Author
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Marina Touillaud, Rudolf Kaaks, Antonia Trichopoulou, Inger T. Gram, Roy Ehrnström, Nina Roswall, Paula Jakszyn, Ellen Kampman, Kay-Tee Khaw, Elio Riboli, H. Bas Bueno-de-Mesquita, Nerea Larrañaga, Marie-Christine Boutron-Ruault, Eva Ardanaz, Carmen Navarro, Kim Overvad, Eiliv Lund, Naomi E. Allen, Carla H. van Gils, Timothy J. Key, Laudina Rodríguez, Martine M. Ros, Paolo Vineis, María José Sánchez, Vicky Benetou, Lambertus A. Kiemeney, Sabina Sieri, Françoise Clavel-Chapelon, A. Naska, Frederike L. Büchner, Rosario Tumino, Lars Egevad, Nicholas J. Wareham, Mazda Jenab, Heiner Boeing, Jonas Manjer, Nadia Slimani, Anne Tjønneland, Petra H.M. Peeters, Fränzel J.B. Van Duijnhoven, Börje Ljungberg, Paolo Boffetta, Steffen Weikert, Domenico Palli, Jenny Chang-Claude, Salvatore Panico, Göran Hallmans, Büchner, F.L., Bueno-De-Mesquita, H.B., Ros, M.M., Kampman, E., Egevad, L., Overvad, K., Tjãnneland, A., Roswall, N., Clavel-Chapelon, F., Boutron-Ruault, M.-C., Touillaud, M., Kaaks, R., Chang-Claude, J., Boeing, H., Weikert, S., Trichopoulou, A., Naska, A., Benetou, V., Palli, D., Sieri, S., Vineis, P., Tumino, R., Panico, S., Van Duijnhoven, F.J.B., Peeters, P.H.M., Van Gils, C.H., Lund, E., Gram, I.T., Sánchez, M.-J., Jakszyn, P., Larrañaga, N., Ardanaz, E., Navarro, C., Rodríguez, L., Manjer, J., Ehrnström, R., Hallmans, G., Ljungberg, B., Key, T.J., Allen, N.E., Khaw, K.-T., Wareham, N., Slimani, N., Jenab, M., Boffetta, P., Kiemeney, L.A.L.M., and Riboli, E.
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Male ,Cancer Research ,validity ,Nutrition and Disease ,Colorectal cancer ,pharyngeal cancer ,Food group ,0302 clinical medicine ,Risk Factors ,diet diversity ,Voeding en Ziekte ,Vegetables ,vegetable ,030212 general & internal medicine ,Prospective Studies ,Prospective cohort study ,bladder ,risk ,2. Zero hunger ,Hazard ratio ,3. Good health ,European Prospective Investigation into Cancer and Nutrition ,Europe ,Oncology ,030220 oncology & carcinogenesis ,food groups ,Female ,colon-cancer ,medicine.medical_specialty ,Molecular epidemiology [NCEBP 1] ,03 medical and health sciences ,Translational research [ONCOL 3] ,Environmental health ,medicine ,cancer ,Humans ,consumption ,Risk factor ,Life Style ,Molecular epidemiology Aetiology, screening and detection [NCEBP 1] ,VLAG ,Gynecology ,Bladder cancer ,business.industry ,cigarette-smoking ,questionnaire ,colorectal-cancer ,Cancer ,medicine.disease ,Diet ,Urinary Bladder Neoplasms ,Fruit ,business - Abstract
Contains fulltext : 97508.pdf (Publisher’s version ) (Closed access) Recent research does not show an association between fruit and vegetable consumption and bladder cancer risk. None of these studies investigated variety in fruit and vegetable consumption, which may capture different aspects of consumption. We investigated whether a varied consumption of vegetables and fruits is associated with bladder cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Detailed data on food consumption and complete follow-up for cancer incidence were available for 452,185 participants, who were recruited from ten European countries. After a mean follow-up of 8.7 years, 874 participants were diagnosed with bladder cancer. Diet diversity scores (DDSs) were used to quantify the variety in fruit and vegetable consumption. Multivariable Cox proportional hazard models were used to assess the effect of the DDSs on bladder cancer risk. There was no evidence of a statistically significant association between bladder cancer risk and any of the DDSs when these scores were considered as continuous covariates. However, the hazard ratio (HR) for the highest tertile of the DDS for combined fruit and vegetable consumption was marginally significant compared to the lowest (HR = 1.30, 95% confidence interval: 1.00-1.69, p-trend = 0.05). In EPIC, there is no clear association between a varied fruit and vegetable consumption and bladder cancer risk. This finding provides further evidence for the absence of any strong association between fruit and vegetable consumption as measured by a food frequency questionnaire and bladder cancer risk.
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- 2011
3. Consumption of vegetables and fruit and the risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition
- Author
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Anne Tjønneland, Carlos González, Ole Raaschou-Nielsen, Marina Touillaud, Sabina Sieri, Françoise Clavel-Chapelon, Salvatore Panico, Lambertus A. Kiemeney, Jonas Manjer, Pagona Lagiou, Rudolf Kaaks, Dimitrios Trichopoulos, Nina Roswall, Andrew W. Roddam, Carla H. van Gils, Inger T. Gram, Steffen Weikert, Frederike L. Büchner, Kim Overvad, Paolo Vineis, Roy Ehrnström, Eva Ardanaz, Nadia Slimani, Martine M. Ros, H. Bas Bueno-de-Mesquita, Sheila Bingham, Traci Mouw, Eiliv Lund, Antonia Trichopoulou, Laudina Rodríguez, Göran Hallmans, Lars Egevad, Ellen Kampman, Rosario Tumino, Carmen Enid Martínez, Heiner Boeing, Kay-Tee Khaw, Marie-Christine Boutron-Ruault, Domenico Palli, Dagrun Engeset, Jenny Chang-Claude, Mazda Jenab, Dominique S. Michaud, Carmen Navarro, Naomi E. Allen, Petra H.M. Peeters, Nerea Larrañaga, Elio Riboli, Alina Vrieling, Börje Ljungberg, Paolo Boffetta, Büchner, F.L., Bueno-De-Mesquita, H.B., Ros, M.M., Kampman, E., Egevad, L., Overvad, K., Raaschou-Nielsen, O., Tjønneland, A., Roswall, N., Clavel-Chapelon, F., Boutron-Ruault, M.-C., Touillaud, M., Chang-Claude, J., Kaaks, R., Boeing, H., Weikert, S., Trichopoulou, A., Lagiou, P., Trichopoulos, D., Palli, D., Sieri, S., Vineis, P., Tumino, R., Panico, S., Vrieling, A., Peeters, P.H.M., Van Gils, C.H., Lund, E., Gram, I.T., Engeset, D., Martinez, C., Gonzalez, C.A., Larrañaga, N., Ardanaz, E., Navarro, C., Rodríguez, L., Manjer, J., Ehrnström, R.A., Hallmans, G., Ljungberg, B., Allen, N.E., Roddam, A.W., Bingham, S., Khaw, K.-T., Slimani, N., Boffetta, P., Jenab, M., Mouw, T., Michaud, D.S., Kiemeney, L.A.L.M., Riboli, E., Büchner, Fl, Bueno de Mesquita, Hb, Ros, Mm, Kampman, E, Egevad, L, Overvad, K, Raaschou Nielsen, O, Tjønneland, A, Roswall, N, Clavel Chapelon, F, Boutron Ruault, Mc, Touillaud, M, Chang Claude, J, Kaaks, R, Boeing, H, Weikert, S, Trichopoulou, A, Lagiou, P, Trichopoulos, D, Palli, D, Sieri, S, Vineis, P, Tumino, R, Panico, Salvatore, Vrieling, A, Peeters, Ph, van Gils, Ch, Lund, E, Gram, It, Engeset, D, Martinez, C, Gonzalez, Ca, Larrañaga, N, Ardanaz, E, Navarro, C, Rodríguez, L, Manjer, J, Ehrnström, Ra, Hallmans, G, Ljungberg, B, Allen, Ne, Roddam, Aw, Bingham, S, Khaw, Kt, Slimani, N, Boffetta, P, Jenab, M, Mouw, T, Michaud, D, and Kiemeney, La
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Male ,Cancer Research ,Nutrition and Disease ,Aetiology, screening and detection [ONCOL 5] ,Cohort Studies ,0302 clinical medicine ,Risk Factors ,Voeding en Ziekte ,Vegetables ,Epidemiology ,Prospective Studies ,030212 general & internal medicine ,Prospective cohort study ,2. Zero hunger ,carotenoids ,Middle Aged ,3. Good health ,European Prospective Investigation into Cancer and Nutrition ,Oncology ,030220 oncology & carcinogenesis ,Female ,epidemiology ,vitamin-c ,Cohort study ,Adult ,medicine.medical_specialty ,prospective cohort ,consumption vegetables fruit risk bladder cancer European Prospective Investigation Cancer Nutrition ,folate ,Molecular epidemiology [NCEBP 1] ,03 medical and health sciences ,Translational research [ONCOL 3] ,Environmental health ,medicine ,Humans ,Risk factor ,Aged ,VLAG ,Consumption (economics) ,Gynecology ,Bladder cancer ,Hereditary cancer and cancer-related syndromes [ONCOL 1] ,cigarette-smoking ,business.industry ,food ,Cancer ,medicine.disease ,Urinary Bladder Neoplasms ,Fruit ,diet ,business ,Follow-Up Studies - Abstract
Contains fulltext : 81056.pdf (Publisher’s version ) (Closed access) Previous epidemiologic studies found inconsistent associations between vegetables and fruit consumption and the risk of bladder cancer. We therefore investigated the association between vegetable and fruit consumption and the risk of bladder cancer among participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Data on food consumption and complete follow-up for cancer occurrence was available for a total of 478,533 participants, who were recruited in 10 European countries. Estimates of rate ratios were obtained by Cox proportional hazard models, stratified by age at recruitment, gender and study centre, and adjusted for total energy intake, smoking status, duration of smoking and lifetime intensity of smoking. A calibration study in a subsample was used to control for dietary measurement errors. After a mean follow-up of 8.7 years, 1015 participants were newly diagnosed with bladder cancer. Increments of 100 g/day in fruit and vegetable consumption combined did not affect bladder cancer risk (i.e., calibrated HR = 0.98; 95%CI: 0.95-1.01). Borderline statistically significant lower bladder cancer risks were found among never smokers with increased consumption of fruit and vegetables combined (HR = 0.94 95%CI: 0.87-1.00 with increments of 100 g/day; calibrated HR = 0.92 95%CI 0.79-1.06) and increased consumption of apples and pears (hard fruit; calibrated HR = 0.90 95%CI: 0.82-0.98 with increments of 25 g/day). For none of the associations a statistically significant interaction with smoking status was found. Our findings do not support an effect of fruit and vegetable consumption, combined or separately, on bladder cancer risk.
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- 2009
4. Fruit and vegetable consumption and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition
- Author
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Kim Overvad, H. Bas Bueno-de-Mesquita, Zilis Dimosthenes, Elio Riboli, Dominique S. Michaud, Göran Hallmans, Sabina Sieri, Bas A.J. Verhage, Carla H. van Gils, Rudolf Kaaks, Paolo Boffetta, Eric J. Duell, Laudina Rodríguez Suárez, Domenico Palli, Amalia Mattiello, Françoise Clavel-Chapelon, Jonas Manjer, Petra H.M. Peeters, Eiliv Lund, Dagrun Engeset, Weimin Ye, Alina Vrieling, Mazda Jenab, Fränzel J.B. Van Duijnhoven, Sheila Bingham, Björn Lindkvist, Antonia Trichopoulou, Sabine Rohrmann, Anja Olsen, Eva Ardanaz, María José Sánchez, Heiner Boeing, Nerea Larrañaga, Anne Tjønneland, María Dolores Chirlaque, Kay-Tee Khaw, Tountas John, Rosario Tumino, Ute Nöthlings, Paolo Vineis, Paula Jakszyn, Marie-Christine Boutron-Ruault, Timothy J. Key, Andrew W. Roddam, Vrieling, A., Verhage, B.A.J., Van Duijnhoven, F.J.B., Jenab, M., Overvad, K., Tjønneland, A., Olsen, A., Clavel-Chapelon, F., Boutron-Ruault, M.-C., Kaaks, R., Rohrmann, S., Boeing, H., Nöthlings, U., Trichopoulou, A., John, T., Dimosthenes, Z., Palli, D., Sieri, S., Mattiello, A., Tumino, R., Vineis, P., Van Gils, C.H., Peeters, P.H.M., Engeset, D., Lund, E., Suárez, L.R., Jakszyn, P., Larrañaga, N., Sánchez, M.-J., Chirlaque, M.-D., Ardanaz, E., Manjer, J., Lindkvist, B., Hallmans, G., Ye, W., Bingham, S., Khaw, K.-T., Roddam, A., Key, T., Boffetta, P., Duell, E.J., Michaud, D.S., Riboli, E., and Bueno-de-Mesquita, H.B.
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Male ,Risk ,Cancer Research ,medicine.medical_specialty ,Nutritional Sciences ,Lower risk ,Cohort Studies ,Environmental health ,Internal medicine ,Vegetables ,medicine ,Humans ,vegetable ,Risk factor ,Prospective cohort study ,Aged ,Proportional Hazards Models ,business.industry ,Smoking ,Hazard ratio ,pancreatic cancer risk ,Cancer ,Middle Aged ,medicine.disease ,Diet ,European Prospective Investigation into Cancer and Nutrition ,Europe ,Pancreatic Neoplasms ,Endocrinology ,Oncology ,Fruit ,Exocrine pancreatic cancer ,Female ,business ,Cohort study - Abstract
Udgivelsesdato: 2008-Nov-7 Many case-control studies have suggested that higher consumption of fruit and vegetables is associated with a lower risk of pancreatic cancer, whereas cohort studies do not support such an association. We examined the associations of the consumption of fruits and vegetables and their main subgroups with pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC is comprised of over 520,000 subjects recruited from 10 European countries. The present study included 555 exocrine pancreatic cancer cases after an average follow-up of 8.9 years. Estimates of risk were obtained by Cox proportional hazard models, stratified by age at recruitment, gender, and study center, and adjusted for total energy intake, weight, height, history of diabetes mellitus, and smoking status. Total consumption of fruit and vegetables, combined or separately, as well as subgroups of vegetables and fruits were unrelated to risk of pancreatic cancer. Hazard ratios (95% CI) for the highest versus the lowest quartile were 0.92 (0.68-1.25) for total fruit and vegetables combined, 0.99 (0.73-1.33) for total vegetables, and 1.02 (0.77-1.36) for total fruits. Stratification by gender or smoking status, restriction to microscopically verified cases, and exclusion of the first 2 years of follow-up did not materially change the results. These results from a large European prospective cohort suggest that higher consumption of fruit and vegetables is not associated with decreased risk of pancreatic cancer. (c) 2008 Wiley-Liss, Inc.
- Published
- 2009
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