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Your search keyword '"Gapstur, Susan M."' showing total 26 results
Start Over Author "Gapstur, Susan M." Journal international journal of cancer
26 results on '"Gapstur, Susan M."'

1. Abdominal and gluteofemoral size and risk of liver cancer: The liver cancer pooling project

Author

Florio, Andrea A, Campbell, Peter T, Zhang, Xuehong, Zeleniuch‐Jacquotte, Anne, Wactawski‐Wende, Jean, Smith‐Warner, Stephanie A, Sinha, Rashmi, Simon, Tracey G, Sesso, Howard D, Schairer, Catherine, Rosenberg, Lynn, Rohan, Thomas E, Robien, Kim, Renehan, Andrew G, Purdue, Mark P, Poynter, Jenny N, Palmer, Julie R, Newton, Christina C, Lu, Yunxia, Linet, Martha S, Liao, Linda M, Lee, I‐Min, Koshiol, Jill, Kitahara, Cari M, Kirsh, Victoria A, Hofmann, Jonathan N, Graubard, Barry I, Giovannucci, Edward, Gaziano, John M, Gapstur, Susan M, Freedman, Neal D, Demuth, Jane, Chong, Dawn Q, Chan, Andrew T, Buring, Julie E, Bradshaw, Patrick T, Freeman, Laura E Beane, McGlynn, Katherine A, and Petrick, Jessica L

Subjects
Obesity, Rare Diseases, Cancer, Liver Disease, Digestive Diseases, Clinical Research, Liver Cancer, Prevention, Adiposity, Adult, Aged, Bile Duct Neoplasms, Body Mass Index, Carcinoma, Hepatocellular, Cholangiocarcinoma, Female, Humans, Liver Neoplasms, Male, Middle Aged, Prospective Studies, Waist Circumference, Waist-Hip Ratio, hepatocellular carcinoma, intrahepatic cholangiocarcinoma, abdominal obesity, gluteofemoral obesity, epidemiology, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract

Obesity is known to be associated with primary liver cancer (PLC), but the separate effects of excess abdominal and gluteofemoral size are unclear. Thus, we examined the association between waist and hip circumference with risk of PLC overall and by histologic type-hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). The Liver Cancer Pooling Project is a consortium of prospective cohort studies that include data from 1,167,244 individuals (PLC n = 2,208, HCC n = 1,154, ICC n = 335). Multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (CI) were estimated using proportional hazards regression. Waist circumference, per 5 cm increase, was associated with an 11% increased PLC risk (HR = 1.11, 95%CI: 1.09-1.14), including when adjusted for hip circumference (HR = 1.12, 95%CI: 1.08-1.17) and also when restricted to individuals in a normal body mass index (BMI) range (18.5 to

Published
2020

2. Generalizability of established prostate cancer risk variants in men of African ancestry

Author

Han, Ying, Signorello, Lisa B, Strom, Sara S, Kittles, Rick A, Rybicki, Benjamin A, Stanford, Janet L, Goodman, Phyllis J, Berndt, Sonja I, Carpten, John, Casey, Graham, Chu, Lisa, Conti, David V, Rand, Kristin A, Diver, W Ryan, Hennis, Anselm JM, John, Esther M, Kibel, Adam S, Klein, Eric A, Kolb, Suzanne, Le Marchand, Loic, Leske, M Cristina, Murphy, Adam B, Neslund‐Dudas, Christine, Park, Jong Y, Pettaway, Curtis, Rebbeck, Timothy R, Gapstur, Susan M, Zheng, S Lilly, Wu, Suh‐Yuh, Witte, John S, Xu, Jianfeng, Isaacs, William, Ingles, Sue A, Hsing, Ann, Consortium, The PRACTICAL, Consortium, The ELLIPSE GAME‐ON, Easton, Douglas F, Eeles, Rosalind A, Schumacher, Fredrick R, Chanock, Stephen, Nemesure, Barbara, Blot, William J, Stram, Daniel O, Henderson, Brian E, and Haiman, Christopher A

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Prostate Cancer, Aging, Prevention, Genetics, Human Genome, Clinical Research, Urologic Diseases, Aetiology, 2.1 Biological and endogenous factors, Black People, Case-Control Studies, Cohort Studies, Follow-Up Studies, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Male, Polymorphism, Single Nucleotide, Prognosis, Prostatic Neoplasms, Risk Factors, prostate cancer, genetic risk variant, generalizability, African ancestry, PRACTICAL Consortium, ELLIPSE GAME-ON Consortium, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

Genome-wide association studies have identified more than 80 risk variants for prostate cancer, mainly in European or Asian populations. The generalizability of these variants in other racial/ethnic populations needs to be understood before the loci can be used widely in risk modeling. In our study, we examined 82 previously reported risk variants in 4,853 prostate cancer cases and 4,678 controls of African ancestry. We performed association testing for each variant using logistic regression adjusted for age, study and global ancestry. Of the 82 known risk variants, 68 (83%) had effects that were directionally consistent in their association with prostate cancer risk and 30 (37%) were significantly associated with risk at p < 0.05, with the most statistically significant variants being rs116041037 (p = 3.7 × 10(-26) ) and rs6983561 (p = 1.1 × 10(-16) ) at 8q24, as well as rs7210100 (p = 5.4 × 10(-8) ) at 17q21. By exploring each locus in search of better markers, the number of variants that captured risk in men of African ancestry (p < 0.05) increased from 30 (37%) to 44 (54%). An aggregate score comprised of these 44 markers was strongly associated with prostate cancer risk [per-allele odds ratio (OR) = 1.12, p = 7.3 × 10(-98) ]. In summary, the consistent directions of effects for the vast majority of variants in men of African ancestry indicate common functional alleles that are shared across populations. Further exploration of these susceptibility loci is needed to identify the underlying biologically relevant variants to improve prostate cancer risk modeling in populations of African ancestry.

Published
2015

3. A comprehensive analysis of polymorphic variants in steroid hormone and insulin‐like growth factor‐1 metabolism and risk of in situ breast cancer: Results from the Breast and Prostate Cancer Cohort Consortium

Author

Barrdahl, Myrto, Canzian, Federico, Gaudet, Mia M., Gapstur, Susan M., Trichopoulou, Antonia, Tsilidis, Kostas, van Gils, Carla H., Borgquist, Signe, Weiderpass, Elisabete, Khaw, Kay‐Tee, Giles, Graham G., Milne, Roger L., Le Marchand, Loic, Haiman, Christopher, Lindström, Sara, Kraft, Peter, Hunter, David J., Ziegler, Regina, Chanock, Stephen J., Yang, Xiaohong R., Buring, Julie E., Lee, I‐Min, Kaaks, Rudolf, and Campa, Daniele

Published
2018
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4. Gene–environment interactions involving functional variants: Results from the Breast Cancer Association Consortium

Author

Barrdahl, Myrto, Rudolph, Anja, Hopper, John L., Southey, Melissa C., Broeks, Annegien, Fasching, Peter A., Beckmann, Matthias W., Gago‐Dominguez, Manuela, Castelao, J. Esteban, Guénel, Pascal, Truong, Thérèse, Bojesen, Stig E., Gapstur, Susan M., Gaudet, Mia M., Brenner, Hermann, Arndt, Volker, Brauch, Hiltrud, Hamann, Ute, Mannermaa, Arto, Lambrechts, Diether, Jongen, Lynn, Flesch‐Janys, Dieter, Thoene, Kathrin, Couch, Fergus J., Giles, Graham G., Simard, Jacques, Goldberg, Mark S., Figueroa, Jonine, Michailidou, Kyriaki, Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Eilber, Ursula, Behrens, Sabine, Czene, Kamila, Hall, Per, Cox, Angela, Cross, Simon, Swerdlow, Anthony, Schoemaker, Minouk J., Dunning, Alison M., Kaaks, Rudolf, Pharoah, Paul D.P., Schmidt, Marjanka, Garcia‐Closas, Montserrat, Easton, Douglas F., Milne, Roger L., and Chang‐Claude, Jenny

Published
2017
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5. Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia

Author

Gu, Fangyi, Zhang, Han, Hyland, Paula L., Berndt, Sonja, Gapstur, Susan M., Wheeler, William, ELLIPSE consortium*, the, Amos, Christopher I., Bezieau, Stephane, Bickeböller, Heike, Brenner, Hermann, Brennan, Paul, Chang‐Claude, Jenny, Conti, David V, Doherty, Jennifer Anne, Gruber, Stephen B, Harrison, Tabitha A, Hayes, Richard B, Hoffmeister, Michael, Houlston, Richard S, Hung, Rayjean J., Jenkins, Mark A., Kraft, Peter, Lawrenson, Kate, McKay, James, Markt, Sarah, Mucci, Lorelei, Phelan, Catherine M., Qu, Conghui, Risch, Angela, Rossing, Mary Anne, Wichmann, H.‐Erich, Shi, Jianxin, Schernhammer, Eva, Yu, Kai, Landi, Maria Teresa, and Caporaso, Neil E.

Published
2017
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6. Association of breast cancer risk loci with breast cancer survival

Author

Barrdahl, Myrto, Canzian, Federico, Lindström, Sara, Shui, Irene, Black, Amanda, Hoover, Robert N., Ziegler, Regina G., Buring, Julie E., Chanock, Stephen J., Diver, Ryan W., Gapstur, Susan M., Gaudet, Mia M., Giles, Graham G., Haiman, Christopher, Henderson, Brian E., Hankinson, Susan, Hunter, David J., Joshi, Amit D., Kraft, Peter, Lee, I-Min, Le Marchand, Loic, Milne, Roger L., Southey, Melissa C., Willett, Walter, Gunter, Marc, Panico, Salvatore, Sund, Malin, Weiderpass, Elisabete, Sánchez, María-José, Overvad, Kim, Dossus, Laure, Peeters, Petra H, Khaw, Kay-Tee, Trichopoulos, Dimitrios, Kaaks, Rudolf, and Campa, Daniele

Published
2015
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7. Intrauterine devices and endometrial cancer risk: A pooled analysis of the Epidemiology of Endometrial Cancer Consortium

Author

Felix, Ashley S., Gaudet, Mia M., Vecchia, Carlo La, Nagle, Christina M., Shu, Xiao Ou, Weiderpass, Elisabete, Adami, Hans Olov, Beresford, Shirley, Bernstein, Leslie, Chen, Chu, Cook, Linda S., Vivo, Immaculata De, Doherty, Jennifer A., Friedenreich, Christine M., Gapstur, Susan M., Hill, Dierdre, Horn-Ross, Pamela L., Lacey, James V., Levi, Fabio, Liang, Xiaolin, Lu, Lingeng, Magliocco, Anthony, McCann, Susan E., Negri, Eva, Olson, Sara H., Palmer, Julie R., Patel, Alpa V., Petruzella, Stacey, Prescott, Jennifer, Risch, Harvey A., Rosenberg, Lynn, Sherman, Mark E., Spurdle, Amanda B., Webb, Penelope M., Wise, Lauren A., Xiang, Yong-Bing, Xu, Wanghong, Yang, Hannah P., Yu, Herbert, Zeleniuch-Jacquotte, Anne, and Brinton, Louise A.

Published
2015
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9. Insulin-like growth factor pathway genes and blood concentrations, dietary protein and risk of prostate cancer in the NCI Breast and Prostate Cancer Cohort Consortium (BPC3)

Author

Tsilidis, Konstantinos K., Travis, Ruth C., Appleby, Paul N., Allen, Naomi E., Lindström, Sara, Albanes, Demetrius, Ziegler, Regina G., McCullough, Marjorie L., Siddiq, Afshan, Barricarte, Aurelio, Berndt, Sonja I., Bueno-de-Mesquita, Bas H., Chanock, Stephen J., Crawford, David E., Diver, Ryan W., Gapstur, Susan M., Giovannucci, Edward, Gu, Fangyi, Haiman, Christopher A., Hayes, Richard B., Hunter, David J., Johansson, Mattias, Kaaks, Rudolf, Kolonel, Laurence N., Kraft, Peter, Le Marchand, Loic, Overvad, Kim, Polidoro, Silvia, Riboli, Elio, Schumacher, Fredrick R., Stevens, Victoria L., Trichopoulos, Dimitrios, Virtamo, Jarmo, Willett, Walter C., and Key, Timothy J

Published
2013
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14. Abdominal and gluteofemoral size and risk of liver cancer: The liver cancer pooling project

Author

Florio, Andrea A., primary, Campbell, Peter T., additional, Zhang, Xuehong, additional, Zeleniuch‐Jacquotte, Anne, additional, Wactawski‐Wende, Jean, additional, Smith‐Warner, Stephanie A., additional, Sinha, Rashmi, additional, Simon, Tracey G., additional, Sesso, Howard D., additional, Schairer, Catherine, additional, Rosenberg, Lynn, additional, Rohan, Thomas E., additional, Robien, Kim, additional, Renehan, Andrew G., additional, Purdue, Mark P., additional, Poynter, Jenny N., additional, Palmer, Julie R., additional, Newton, Christina C., additional, Lu, Yunxia, additional, Linet, Martha S., additional, Liao, Linda M., additional, Lee, I‐Min, additional, Koshiol, Jill, additional, Kitahara, Cari M., additional, Kirsh, Victoria A., additional, Hofmann, Jonathan N., additional, Graubard, Barry I., additional, Giovannucci, Edward, additional, Gaziano, John M., additional, Gapstur, Susan M., additional, Freedman, Neal D., additional, Demuth, Jane, additional, Chong, Dawn Q., additional, Chan, Andrew T., additional, Buring, Julie E., additional, Bradshaw, Patrick T., additional, Beane Freeman, Laura E., additional, McGlynn, Katherine A., additional, and Petrick, Jessica L., additional

Published
2019
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16. Ovarian cancer risk factors by tumor aggressiveness: An analysis from the Ovarian Cancer Cohort Consortium

Author

Fortner, Renée T., primary, Poole, Elizabeth M., additional, Wentzensen, Nicolas A., additional, Trabert, Britton, additional, White, Emily, additional, Arslan, Alan A., additional, Patel, Alpa V., additional, Setiawan, V. Wendy, additional, Visvanathan, Kala, additional, Weiderpass, Elisabete, additional, Adami, Hans‐Olov, additional, Black, Amanda, additional, Bernstein, Leslie, additional, Brinton, Louise A., additional, Buring, Julie, additional, Clendenen, Tess V., additional, Fournier, Agnès, additional, Fraser, Gary, additional, Gapstur, Susan M., additional, Gaudet, Mia M., additional, Giles, Graham G., additional, Gram, Inger T., additional, Hartge, Patricia, additional, Hoffman‐Bolton, Judith, additional, Idahl, Annika, additional, Kaaks, Rudolf, additional, Kirsh, Victoria A., additional, Knutsen, Synnove, additional, Koh, Woon‐Puay, additional, Lacey, James V., additional, Lee, I‐Min, additional, Lundin, Eva, additional, Merritt, Melissa A., additional, Milne, Roger L., additional, Onland‐Moret, N. Charlotte, additional, Peters, Ulrike, additional, Poynter, Jenny N., additional, Rinaldi, Sabina, additional, Robien, Kim, additional, Rohan, Thomas, additional, Sánchez, Maria‐José, additional, Schairer, Catherine, additional, Schouten, Leo J., additional, Tjonneland, Anne, additional, Townsend, Mary K., additional, Travis, Ruth C., additional, Trichopoulou, Antonia, additional, Brandt, Piet A., additional, Vineis, Paolo, additional, Wilkens, Lynne, additional, Wolk, Alicja, additional, Yang, Hannah P., additional, Zeleniuch‐Jacquotte, Anne, additional, and Tworoger, Shelley S., additional

Published
2019
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17. A comprehensive analysis of polymorphic variants in steroid hormone and insulin-like growth factor-1 metabolism and risk of in situ breast cancer: Results from the Breast and Prostate Cancer Cohort Consortium

Author

Barrdahl, Myrto, Canzian, Federico, Gaudet, Mia M., Gapstur, Susan M., Trichopoulou, Antonia, Tsilidis, Kostas, van Gils, Carla H., Borgquist, Signe, Weiderpass, Elisabete, Khaw, Kay-Tee, Giles, Graham G., Milne, Roger L., Le Marchand, Loic, Haiman, Christopher, Lindstrã¶m, Sara, Kraft, Peter, Hunter, David J., Ziegler, Regina, Chanock, Stephen J., Yang, Xiaohong R., Buring, Julie E., Lee, I-Min, Kaaks, Rudolf, and Campa, Daniele

Subjects
Cancer Research, genetic epidemiology, GENES, SUSCEPTIBILITY LOCI, Activin Receptors, Type II, BPC3, Breast cancer in situ, Genetic epidemiology, Single nucleotide polymorphisms, Oncology, Breast Neoplasms, Promyelocytic Leukemia Protein, Protein Serine-Threonine Kinases, Polymorphism, Single Nucleotide, 5P12, Article, single nucleotide polymorphisms, Antigens, CD, CONFER SUSCEPTIBILITY, Humans, Genetic Predisposition to Disease, Oncology & Carcinogenesis, Prospective Studies, GENOME-WIDE ASSOCIATION, Insulin-Like Growth Factor I, Gonadal Steroid Hormones, Aged, Science & Technology, breast cancer in situ, PML, COMMON VARIANTS, Middle Aged, Introns, Receptor, Insulin, Case-Control Studies, Female, Breast Carcinoma In Situ, Life Sciences & Biomedicine, LEUKEMIA, 1112 Oncology And Carcinogenesis, Microtubule-Associated Proteins
Abstract

We assessed the association between 1,414 single nucleotide polymorphisms (SNPs) in genes involved in synthesis and metabolism of steroid hormones and insulin-like growth factor 1, and risk of breast cancer in situ (BCIS), with the aim of determining whether any of these were disease specific. This was carried out using 1,062 BCIS cases and 10,126 controls as well as 6,113 invasive breast cancer cases from the Breast and Prostate Cancer Cohort Consortium (BPC3). Three SNPs showed at least one nominally significant association in homozygous minor versus homozygous major models. ACVR2A-rs2382112 (OR(hom) = 3.05, 95%CI = 1.72–5.44, P(hom) = 1.47 × 10(−4)), MAST2-rs12124649 (OR(hom) = 1.73, 95% CI =1.18–2.54, P(hom) = 5.24 × 10(−3)), and INSR-rs10500204 (OR(hom) = 1.96, 95% CI = 1.44–2.67, P(hom)=1.68 × 10(−5)) were associated with increased risk of BCIS; however, only the latter association was significant after correcting for multiple testing. Furthermore, INSR-rs10500204 was more strongly associated with the risk of BCIS than invasive disease in case-only analyses using the homozygous minor versus homozygous major model (OR(hom) = 1.78, 95% CI = 1.30–2.44, P(hom) = 3.23 × 10(−4)). The SNP INSR-rs10500204 is located in an intron of the INSR gene and is likely to affect binding of the promyelocytic leukemia (PML) protein. The PML gene is known as a tumor suppressor and growth regulator in cancer. However, it is not clear on what pathway the A-allele of rs10500204 could operate to influence the binding of the protein. Hence, functional studies are warranted to investigate this further.

Published
2017

18. Blood levels of cadmium and lead in relation to breast cancer risk in three prospective cohorts

Author

Gaudet, Mia M., primary, Deubler, Emily L., additional, Kelly, Rachel S., additional, Ryan Diver, W., additional, Teras, Lauren R., additional, Hodge, James M., additional, Levine, Keith E., additional, Haines, Laura G., additional, Lundh, Thomas, additional, Lenner, Per, additional, Palli, Domenico, additional, Vineis, Paolo, additional, Bergdahl, Ingvar A., additional, Gapstur, Susan M., additional, and Kyrtopoulos, Soterios A., additional

Published
2018
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19. Blood levels of cadmium and lead in relation to breast cancer risk in three prospective cohorts.

Author

Gaudet, Mia M., Deubler, Emily L., Kelly, Rachel S., Ryan Diver, W., Teras, Lauren R., Hodge, James M., Levine, Keith E., Haines, Laura G., Lundh, Thomas, Lenner, Per, Palli, Domenico, Vineis, Paolo, Bergdahl, Ingvar A., Gapstur, Susan M., and Kyrtopoulos, Soterios A.

Abstract

Cadmium and lead have been classified as carcinogens by the International Agency for Research on Cancer. However, their associations with breast cancer risk are unknown despite their persistence in the environment and ubiquitous human exposure. We examined associations of circulating levels of cadmium and lead with breast cancer risk in three case–control studies nested within the Cancer Prevention Study‐II (CPS‐II) LifeLink Cohort, European Prospective Investigation into Cancer and Nutrition – Italy (EPIC‐Italy) and the Northern Sweden Health and Disease Study (NSHDS) cohorts. Metal levels were measured in stored erythrocytes from 1,435 cases and 1,433 controls using inductively coupled plasma‐mass spectrometry. Summary relative risks (RR) and 95% confidence intervals (CI) were calculated using random‐effects models with each study result weighted by the within‐ and between‐study variances. I2 values were calculated to estimate proportion of between study variation. Using common cut‐points, cadmium levels were not associated with breast cancer risk in the CPS‐II cohort (continuous RR = 1.01, 95% CI 0.76–1.34), but were inversely associated with risk in the EPIC‐ Italy (continuous RR = 0.80, 95% CI 0.61–1.03) and NSHDS cohorts (continuous RR = 0.73, 95% CI 0.54–0.97). The inverse association was also evident in the meta‐analysis (continuous RR = 0.84, 95% CI 0.69–1.01) with low between‐study heterogeneity. Large differences in lead level distributions precluded a meta‐analysis of their association with breast cancer risk; no associations were found in the three studies. Adult cadmium and lead levels were not associated with higher risk of breast cancer in our large meta‐analysis. What's new? Do cadmium and lead cause breast cancer? These two notorious toxic metals tend to linger in the body, and both are classified as carcinogens. Ubiquitous environmental contaminants, they accumulate in women particularly, due to their lower iron levels. Yet no definitive link has been demonstrated between cadmium or lead and breast cancer. Here, the authors analyzed three case–control studies. Across the three studies, a wide range of exposure levels was represented, and each study included a large number of participants. The meta‐analysis revealed no association between high levels of cadmium or lead and breast cancer risk. [ABSTRACT FROM AUTHOR]

Published
2019
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20. A comprehensive analysis of polymorphic variants in steroid hormone and insulin‐like growth factor‐1 metabolism and risk of <italic>in situ</italic> breast cancer: Results from the Breast and Prostate Cancer Cohort Consortium.

Author

Barrdahl, Myrto, Canzian, Federico, Gaudet, Mia M., Gapstur, Susan M., Trichopoulou, Antonia, Tsilidis, Kostas, van Gils, Carla H., Borgquist, Signe, Weiderpass, Elisabete, Khaw, Kay‐Tee, Giles, Graham G., Milne, Roger L., Le Marchand, Loic, Haiman, Christopher, Lindström, Sara, Kraft, Peter, Hunter, David J., Ziegler, Regina, Chanock, Stephen J., and Yang, Xiaohong R.

Abstract

We assessed the association between 1,414 single nucleotide polymorphisms (SNPs) in genes involved in synthesis and metabolism of steroid hormones and insulin‐like growth factor 1, and risk of breast cancer in situ (BCIS), with the aim of determining whether any of these were disease specific. This was carried out using 1,062 BCIS cases and 10,126 controls as well as 6,113 invasive breast cancer cases from the Breast and Prostate Cancer Cohort Consortium (BPC3). Three SNPs showed at least one nominally significant association in homozygous minor versus homozygous major models. ACVR2A‐rs2382112 (ORhom = 3.05, 95%CI = 1.72–5.44, Phom = 1.47 × 10−4), MAST2‐rs12124649 (ORhom = 1.73, 95% CI =1.18–2.54, Phom = 5.24 × 10−3), and INSR‐rs10500204 (ORhom = 1.96, 95% CI = 1.44–2.67, Phom=1.68 × 10−5) were associated with increased risk of BCIS; however, only the latter association was significant after correcting for multiple testing. Furthermore, INSR‐rs10500204 was more strongly associated with the risk of BCIS than invasive disease in case‐only analyses using the homozygous minor versus homozygous major model (ORhom = 1.78, 95% CI = 1.30–2.44, Phom = 3.23 × 10−4). The SNP INSR‐rs10500204 is located in an intron of the INSR gene and is likely to affect binding of the promyelocytic leukemia (PML) protein. The PML gene is known as a tumor suppressor and growth regulator in cancer. However, it is not clear on what pathway the A‐allele of rs10500204 could operate to influence the binding of the protein. Hence, functional studies are warranted to investigate this further. [ABSTRACT FROM AUTHOR]

Published
2018
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21. Association of breast cancer risklociwith breast cancer survival

Author

Barrdahl, Myrto, primary, Canzian, Federico, additional, Lindström, Sara, additional, Shui, Irene, additional, Black, Amanda, additional, Hoover, Robert N., additional, Ziegler, Regina G., additional, Buring, Julie E., additional, Chanock, Stephen J., additional, Diver, W. Ryan, additional, Gapstur, Susan M., additional, Gaudet, Mia M., additional, Giles, Graham G., additional, Haiman, Christopher, additional, Henderson, Brian E., additional, Hankinson, Susan, additional, Hunter, David J., additional, Joshi, Amit D., additional, Kraft, Peter, additional, Lee, I-Min, additional, Le Marchand, Loic, additional, Milne, Roger L., additional, Southey, Melissa C., additional, Willett, Walter, additional, Gunter, Marc, additional, Panico, Salvatore, additional, Sund, Malin, additional, Weiderpass, Elisabete, additional, Sánchez, María-José, additional, Overvad, Kim, additional, Dossus, Laure, additional, Peeters, Petra H, additional, Khaw, Kay-Tee, additional, Trichopoulos, Dimitrios, additional, Kaaks, Rudolf, additional, and Campa, Daniele, additional

Published
2015
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22. Intrauterine devices and endometrial cancer risk: A pooled analysis of the Epidemiology of Endometrial Cancer Consortium

Author

Felix, Ashley S., primary, Gaudet, Mia M., additional, Vecchia, Carlo La, additional, Nagle, Christina M., additional, Shu, Xiao Ou, additional, Weiderpass, Elisabete, additional, Adami, Hans Olov, additional, Beresford, Shirley, additional, Bernstein, Leslie, additional, Chen, Chu, additional, Cook, Linda S., additional, Vivo, Immaculata De, additional, Doherty, Jennifer A., additional, Friedenreich, Christine M., additional, Gapstur, Susan M., additional, Hill, Dierdre, additional, Horn‐Ross, Pamela L., additional, Lacey, James V., additional, Levi, Fabio, additional, Liang, Xiaolin, additional, Lu, Lingeng, additional, Magliocco, Anthony, additional, McCann, Susan E., additional, Negri, Eva, additional, Olson, Sara H., additional, Palmer, Julie R., additional, Patel, Alpa V., additional, Petruzella, Stacey, additional, Prescott, Jennifer, additional, Risch, Harvey A., additional, Rosenberg, Lynn, additional, Sherman, Mark E., additional, Spurdle, Amanda B., additional, Webb, Penelope M., additional, Wise, Lauren A., additional, Xiang, Yong‐Bing, additional, Xu, Wanghong, additional, Yang, Hannah P., additional, Yu, Herbert, additional, Zeleniuch‐Jacquotte, Anne, additional, and Brinton, Louise A., additional

Published
2014
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