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Start Over Author "Loukas, Alex" Topic cytokinins Topic schistosoma mansoni Journal international journal for parasitology
1 results on '"Loukas, Alex"'

1. Reversible paralysis of Schistosoma mansoni by forchlorfenuron, a phenylurea cytokinin that affects septins.

Author

Zeraik, Ana E., Galkin, Vitold E., Rinaldi, Gabriel, Garratt, Richard C., Smout, Michael J., Loukas, Alex, Mann, Victoria H., Araujo, Ana P.U., DeMarco, Ricardo, and Brindley, Paul J.

Subjects
*SCHISTOSOMA mansoni, *PHENYLUREA compounds, *CYTOKININS, *SEPTINS, *POLYMERIZATION, *PARALYSIS
Abstract

Highlights: [•] Schistosome septins assemble into complexes and higher-order structures, including filaments and rings. [•] Polymerization of schistosome septins hastened in forchlorfenuron (FCF), a phenylurea cytokinin. [•] FCF led to a striking paralysis phenotype in cercariae and adult schistosomes. [•] The paralysis was reversible, but FCF dose- and time-dependent. [ABSTRACT FROM AUTHOR]

Published
2014
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