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This work proposes a novel technique to conduct back‐analysis of lateral displacement of deep cement mixing (DCM) columns in deep excavation construction. For the first time, we propose a process to investigate both soil and underground structure end‐to‐end automatically. The novel technique is a complex combination of three crucial factors: (1) a nature‐inspired optimization algorithm (O), (2) a three‐dimensional PLAXIS Geotechnical Engineering software (P) and (3) a modern Python language programming (P), hereinafter called the a nature‐inspired optimization algorithm (O), a three‐dimensional PLAXIS Geotechnical Engineering software (P) and a modern Python language programming (P) (OPP) technique. The novel meta‐heuristic algorithm simulated the co‐evolved partnership behavior of shrimps and goby fishes, termed Shrimp and Goby Association (SGA), which plays an important role in complex analyses. A series of exams to determine the SGA's performance is conducted on 38 benchmark test functions (IEEE Congress on Evolutionary Computation 2017 and 2019) and three real‐world engineering design problems to showcase its applicability. The metaheuristic and PLAXIS 3D analysis work well together, which makes the back‐analysis technique powerfully to determinate stiffness parameters instead of the traditional approaches. Based on the optimized parameters, the lateral deflection of DCM and soil are well predicted for excavation. This study proposes a technique to estimate efficiently the stiffness parameter for very soft soil. As a consequence of the optimization process, an equation to determine the stiffness parameter of DCM columns from laboratory test is also proposed. Based on the obtained results, this research provides a comprehensive methodology for predicting risk, enhancing safety, saving time and money, and effectively designing and constructing underground structures. [ABSTRACT FROM AUTHOR]