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Background: The treatment of people living with AIDS , known a highly active antiretroviral therapy (HAART), has increased considerably, and the disease has therefore acquired chronic features. Several changes have been observed, especially in cardiovascular disease risk. Objective: To assess cardiovascular risk in HIV/AIDS patients treated with HAART and compare this with Lipodystrophy Syndrome (LS) carriers. Methods: This is a descriptive cross-sectional study. 192 patients were recruited from a lipodystrophy outpatient centre, using Framingham risk scores. Results: After criteria inclusion/exclusion, the final sample consisted of 81 patients divided into two groups (HIV/AIDS - without lipodystrophy and HIV/LS - with lipodystrophy). The mean age of HIV/AIDS was 46.5 years, and of the HIV/LS patients was 52 years. In accordance with Framingham scores the cardiovascular risk in HIV/AIDS was 46.59% and 14.29% in HIV/LS. Conclusion: The risk of cardiovascular disease over 10 years is significantly higher in patients with lipodystrophy syndrome.

Background: The literature indicates that chronic obstructive pulmonary disease (COPD) affects cardiac autonomic control. In this study, we conducted a literature review in order to investigate the heart rate variability (HRV) in COPD subjects. Methods: A search was performed in Medline database, using the link between the keywords: “autonomic nervous system”, “cardiovascular system”, “COPD” and “heart rate variability”. Results: The search resulted in a total of 40 references. Amongst these references, the first exclusion resulted in the barring of 29 titles and abstracts, which were not clearly related to the purpose of review. This resulted in a total of 11 articles that were then read and utilized in the review. The selected studies indicated that there is significant reduction of HRV in patients with COPD, characterized by reduction of indices that assess parasympathetic activity in addition to dealing with the global autonomic modulation. We also established that supervised exercise can reduce these harmful effects in COPD patients. Also, it was reported that the use of non-invasive ventilation in these patients may contribute to the improvement of respiratory symptoms, with no impairing, and may even induce positive responses in cardiac autonomic regulation. Conclusion: The studies indicate a need for further investigations to guide future therapies to improve the treatment of cardiovascular system in the respiratory diseases.

Made available in DSpace on 2022-04-29T07:12:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-10-28 Background: Chronic exposure to musical auditory stimulation has been reported to improve cardiac autonomic regulation. However, it is not clear if music acutely influences it in response to autonomic tests. We evaluated the acute effects of music on heart rate variability (HRV) responses to the postural change maneuver (PCM) in women. Method. We evaluated 12 healthy women between 18 and 28 years old and HRV was analyzed in the time (SDNN, RMSSD, NN50 and pNN50) and frequency (LF, HF and LF/HF ratio) domains. In the control protocol, the women remained at seated rest for 10 minutes and quickly stood up within three seconds and remained standing still for 15 minutes. In the music protocol, the women remained at seated rest for 10 minutes, were exposed to music for 10 minutes and quickly stood up within three seconds and remained standing still for 15 minutes. HRV was recorded at the following time: rest, music (music protocol) 0-5, 5-10 and 10-15 min during standing. Results: In the control protocol the SDNN, RMSSD and pNN50 indexes were reduced at 10-15 minutes after the volunteers stood up, while the LF (nu) index was increased at the same moment compared to seated rest. In the protocol with music, the indexes were not different from control but the RMSSD, pNN50 and LF (nu) were different from the music period. Conclusion: Musical auditory stimulation attenuates the cardiac autonomic responses to the PCM. © 2013de Castro et al.; licensee BioMed Central Ltd. Department of Speech Language and Hearing Therapy Faculty of Philosophy and Sciences UNESP, Av. Hygino Muzzi Filho 737, 17.525-900 Marilia, SP Department of Medicine Cardiology Division UNIFESP, Rua Sena Madureira 1500, 04021-001 Sao Paulo, SP Department of Morphology and Physiology School of Medicine of ABC, Av. Principe de Gales, 821, 09060-650 Santo Andre, SP School of Arts Sciences and Humanities University of São Paulo USP, Av. Arlindo Béttio, 1000, 03828-000 Sao Paulo, SP Department of Physiotherapy Faculty of Sciences and Technology UNESP, Rua Roberto Simonsen, 305, 19060-900 Presidente Prudente, SP Department of Speech Language and Hearing Therapy Faculty of Philosophy and Sciences UNESP, Av. Hygino Muzzi Filho 737, 17.525-900 Marilia, SP Department of Physiotherapy Faculty of Sciences and Technology UNESP, Rua Roberto Simonsen, 305, 19060-900 Presidente Prudente, SP