7 results on '"Le S."'
Search Results
2. Identify, screen and treat via electronic pathway: a semiautomated approach to retriaging a liver clinic waitlist.
- Author
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Flanagan E, Pianko S, Ho C, Saxby E, Grant J, Bell S, Stuart R, and Le S
- Subjects
- Humans, Male, Female, Middle Aged, Australia, Aged, Adult, Pilot Projects, Hepacivirus genetics, Hepatitis C diagnosis, Referral and Consultation, Waiting Lists, Triage methods, Liver Cirrhosis diagnosis, Liver Cirrhosis blood
- Abstract
Background: Long specialist outpatient waiting lists are a source of clinical risk. Triage assignment is based on subjective assessment of referrals and fails to account for dynamic changes in disease status while patients await clinical review., Aims: To pilot an innovative triage method using a trifold approach to conduct noninvasive assessment of fibrosis and to determine the feasibility of reflex hepatitis C virus (HCV) polymerase chain reaction (PCR) testing., Methods: A total of 1006 patients awaiting an initial liver clinic appointment at a tertiary Australian hospital were sent a short message service (SMS) requesting a blood test be completed. The first 60 patients received an SMS only, and the subsequent 946 patients also received a phone call from a Liver Care Guide (LCG), a nonclinician employed to increase patient engagement. Liver fibrosis assessment through noninvasive testing was performed using an aspartate aminotransferase to platelet ratio index (APRI) and fibrosis-4 (FIB4) score. Patients with an APRI ≥1, FIB4 ≥3.25 or positive HCV PCR were retriaged to Category 1., Results: Four hundred ninety (49%) patients completed testing and 40 (4%) were triaged to Category 1. Subanalyses demonstrated increased response rates with LCG input (P = 0.012). Retriaged patients had been on the waitlist for a median of 216 days, exceeding initial category recommendations., Conclusion: This study successfully implemented a semiautomated strategy that prioritises patients with probable advanced liver disease or active HCV, demonstrating enhanced patient engagement with LCG support. It highlights the burden of patients referred for specialist care and the need for innovative strategies for monitoring and objective risk stratification., (© 2024 The Author(s). Internal Medicine Journal published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Physicians.)
- Published
- 2024
- Full Text
- View/download PDF
3. Clinical outcomes of hepatocellular carcinoma surveillance in Melbourne, Australia.
- Author
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Hui S, Nguyen A, Le S, Dev A, and Bell S
- Subjects
- Humans, Male, Female, Middle Aged, Aged, Adult, Victoria epidemiology, Ultrasonography, Retrospective Studies, Australia epidemiology, Population Surveillance methods, Carcinoma, Hepatocellular epidemiology, Carcinoma, Hepatocellular diagnosis, Carcinoma, Hepatocellular diagnostic imaging, Liver Neoplasms epidemiology, Liver Neoplasms diagnosis, Early Detection of Cancer methods
- Abstract
Background: Ultrasound surveillance for hepatocellular carcinoma (HCC) may improve early tumour detection but may additionally result in surveillance-related harm through increased evaluation of non-HCC lesions. The incidence of these outcomes has not been reported outside North America., Aims: We aimed to report the outcomes of HCC surveillance with respect to both surveillance-related benefits and harms., Methods: We reviewed all HCC surveillance ultrasounds at a large Victorian tertiary hospital network in 2017 and followed their outcomes until 2021. Surveillance-related benefits were defined as early-stage HCC detection. Surveillance-related harm was defined as contrast imaging, biopsies or surgery performed to evaluate non-HCC liver lesions or false-positive alpha-fetoprotein levels., Results: Five hundred and fifty-three patients were included (mean age 54.5 ± 12.3 years, males 67.5%, cirrhosis 50.3%). The most common liver disease aetiology was hepatitis B (53.9%). Over a median of 4.7 years follow-up, early-stage HCC was detected in 3.3% (5.4% in cirrhotic vs 1.1% in non-cirrhotic patients, P < 0.01). 75% of all HCCs were early-stage. Surveillance-related harm occurred in 12.5% (15.5% in cirrhotic vs 9.5% in non-cirrhotic patients, P < 0.04), although most harm was mild (12.1%). In subgroup analysis, the detection of early-stage HCC ranged between 0% (screened outside of guideline criteria and alcoholic cirrhotic patients) and 7.2% (hepatitis C cirrhosis). Harm occurred between 9% (non-cirrhotic hepatitis B) and 20.8% (thrombocytopenia)., Conclusion: In our study, HCC surveillance was associated with early tumour detection, although many patients experienced mild surveillance-related harm. Novel surveillance strategies and pathways are required to improve detection in high-risk patients and minimise harm in low-risk patients., (© 2024 The Authors. Internal Medicine Journal published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Physicians.)
- Published
- 2024
- Full Text
- View/download PDF
4. Impact of increased alcohol consumption during the COVID-19-related lockdowns on admissions with liver disease, gastrointestinal bleeding and pancreatitis in Melbourne, Victoria.
- Author
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Ngu NLY, Boyd DT, Morgan B, Surampudi A, Brown I, Bykersma C, Kennett G, Yesmin A, Peng Y, Bell S, and Le S
- Subjects
- Humans, Communicable Disease Control, Gastrointestinal Hemorrhage, Ethanol, Alcohol Drinking, Hospitalization, Liver, COVID-19, Pancreatitis
- Abstract
This audit collates data on alcohol-related gastrointestinal (GI) admissions at Monash Health, Victoria, during the prolonged, coronavirus disease 2019 (COVID-19)-related lockdown July to October 2020 compared with the same periods in 2019 and 2021. We found a 58% increase in admissions in 2020 and a 16% increase in 2021, which also increased disproportionately to overall health service emergency presentations. Self-reported alcohol consumption increased by 2.5-fold and was greatest in 2020. Clinical severity was unchanged and cirrhosis was the only factor associated with severe disease. This study suggests an association between the pandemic-related lockdown, alcohol consumption and alcohol-related GI hospitalisation. Our study provides support for resourcing and adapting alcohol and other drug services during and beyond the COVID-19 lockdown., (© 2023 The Authors. Internal Medicine Journal published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Physicians.)
- Published
- 2023
- Full Text
- View/download PDF
5. Impact of COVID-19 telehealth on outpatient test completion.
- Author
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Liu TL, Yeo AL, Ravi A, Patabendige G, Lim TW, Bell S, Morand E, and Le S
- Subjects
- Australia, Humans, Outpatients, Pandemics, Prospective Studies, Retrospective Studies, SARS-CoV-2, COVID-19, Telemedicine
- Abstract
Background: Pathology and imaging tests are frequently requested in the outpatient setting despite historically poor completion rates. The impact of COVID-19 telehealth on test completion rates is unknown., Aims: To examine the impact of the COVID-19 pandemic and telehealth transition on pathology and imaging test request and completion rates in Australian outpatient clinics., Methods: We performed a prospective cohort study with historical controls between March-May 2019 and March-May 2020. Pathology and imaging request and completion rates were collected in review consultation patients attending gastroenterology and rheumatology outpatient clinics at a tertiary healthcare system prior and during the early phases of the COVID-19 pandemic in Melbourne., Results: A total of 1376 patients was included in the study. Pathology tests were requested more frequently in the COVID-19 group (n = 582/684, 85.2%) than the control group (n = 492/692, 71.1%, P < 0.001), but completion rates were lower in the COVID-19 group (n = 443/582, 76.1%) than the control group (n = 426/492 (86.6%), P < 0.001). Imaging tests were requested more frequently in the COVID-19 group (n = 345/682, 50.6%) than the control group (n = 295/692, 42.6%, P = 0.003), with lower rates of completion in the COVID-19 group (n = 229/345, 66.4%) than the control group (n = 247/295, 83.7%, P < 0.001)., Conclusions: The COVID-19 pandemic and telehealth transition have resulted in more frequent pathology and imaging requests but fewer test completion in the outpatients setting. This study has identified new clinical risks associated with the abrupt transition to telehealth during COVID-19 that should be explored in future studies and appropriately mitigated., (© 2021 Royal Australasian College of Physicians.)
- Published
- 2021
- Full Text
- View/download PDF
6. The application of telehealth to remote and rural Australians with chronic neurological conditions.
- Author
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Le S and Aggarwal A
- Subjects
- Chronic Disease, Humans, Patient Satisfaction, Rural Population, Victoria, Telemedicine
- Abstract
Background: Patients with chronic disease in rural and remote regions endure limited access to specialised medicine. Telehealth has addressed this issue with demonstrable benefits such as a reduction in costs to patients., Aims: To explore the patient satisfaction of telehealth in Australia., Methods: Patients from all around Australia, including Queensland, Victoria, Tasmania, South Australia, Australian Capital Territory and even Western Australia were referred to a Sydney-based neurologist. After their initial face to face consultation, review consultations were performed by telehealth. All had chronic diseases (trigeminal neuralgia, facial pain or Parkinson disease) and received a standardised questionnaire comprising of demographics, satisfaction of technical aspects and quality of the consultation. The questionnaires were administered by the Practice Manager to remove observer bias., Results: Twenty-nine patient questionnaires were completed by 13 patients who had follow-up telehealth consultations. One hundred per cent of patients reported satisfaction with the overall telehealth experience and would use it again. All were satisfied with the specialist and the privacy. The majority were satisfied with the voice quality (86%), visual quality (79%), ease of connectivity (93%) and length of the consultation (97%). In total, they saved nearly $17 000 in travel costs and on average, each patient avoided 937 km and saved $550., Conclusion: Telehealth has proven to have multiple advantages, including improved access to healthcare, decreased costs, reduced inconvenience and improved management of chronic and complex conditions. The positive results advocate the use of telehealth for follow up of rural and remote patients with chronic disease., (© 2020 Royal Australasian College of Physicians.)
- Published
- 2021
- Full Text
- View/download PDF
7. Acceptability of opt-out consent in a hospital patient population.
- Author
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Boulos D, Morand E, Foo M, Trivedi JD, Lai R, Huntersmith R, Zhang K, Stark CB, and Le S
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Female, Hospitalization trends, Humans, Male, Middle Aged, Young Adult, Electronic Health Records standards, Informed Consent standards, Patient Satisfaction, Surveys and Questionnaires standards
- Abstract
Research has been slow to leverage digitalised medical records as a data resource. Our study assessed patient acceptability of opt-out consent for secondary use of digital patient data. A questionnaire was distributed to patients in multiple languages and with an interpreter. Of 919 completed surveys, 33% were of non-English speaking background, 15% self-reported cognitive impairment and 3% were refugees. Opt-out consent was accepted in this diverse population; 87% of participants approved, or were indifferent to opt-out consent. Gender, employment and cognition status were not significant determinants of acceptability., (© 2018 Royal Australasian College of Physicians.)
- Published
- 2018
- Full Text
- View/download PDF
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