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Your search keyword '"Perentes, Jean"' showing total 9 results
Start Over Author "Perentes, Jean" Journal interactive cardiovascular and thoracic surgery
9 results on '"Perentes, Jean"'

2. Outcome after extracorporeal membrane oxygenation-bridged lung retransplants: a single-centre experience

Author

Abdelnour-Berchtold, Etienne, primary, Federici, Sara, additional, Wurlod, Daniel-Adrien, additional, Bellier, Jocelyn, additional, Zellweger, Matthieu, additional, Kirsch, Matthias, additional, Nicod, Laurent, additional, Marcucci, Carlo, additional, Baeriswyl, Moira, additional, Liaudet, Lucas, additional, Soccal, Paola M, additional, Gonzalez, Michel, additional, Perentes, Jean Yannis, additional, Ris, Hans-Beat, additional, Krueger, Thorsten, additional, and Aubert, John-David, additional

Published
2019
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3. Experimental ex vivo lung perfusion with sevoflurane: effects on damaged donor lung grafts

Author

Wang, Xingyu, primary, Parapanov, Roumen, additional, Francioli, Cyril, additional, Perentes, Jean Yannis, additional, Letovanec, Igor, additional, Gonzalez, Michel, additional, Kern, Christian, additional, Ris, Hans-Beat, additional, Piquilloud, Lise, additional, Marcucci, Carlo, additional, Krueger, Thorsten, additional, Liaudet, Lucas, additional, and Gronchi, Fabrizio, additional

Published
2018
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7. Local control and short-term outcomes after video-assisted thoracoscopic surgery segmentectomy versus lobectomy for pT1c pN0 non-small-cell lung cancer

Author

Forster, Céline, Abdelnour-Berchtold, Etienne, Bédat, Benoît, Perentes, Jean Yannis, Zellweger, Matthieu, Sauvain, Marc-Olivier, Christodoulou, Michel, Triponez, Frédéric, Karenovics, Wolfram, Krueger, Thorsten, and Gonzalez, Michel

Abstract

Lung cancer is a major cause of cancer-related death worldwide with surgical resection remaining the gold standard of treatment for early-stage tumours.

Published
2023
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8. Drug uptake in a rodent sarcoma model after intravenous injection or isolated lung perfusion of free/liposomal doxorubicin.

Author

Cheng, Cai, Haouala, Amina, Krueger, Thorsten, Mithieux, Francois, Perentes, Jean Y, Peters, Solange, Decosterd, Laurent A, and Ris, Hans-Beat

Abstract

The distribution of free and liposomal doxorubicin (Liporubicin) administered by intravenous injection (IV) or isolated lung perfusion (ILP) was compared in normal and tumor tissues of sarcoma bearing rodent lungs. A single sarcomatous tumor was generated in the left lung of 35 Fischer rats, followed 10 days later by left-sided ILP (n=20) or IV drug administration (n=12), using 100 microg and 400 microg free or liposomal doxorubicin, respectively. The tumor and lung tissue drug concentration was measured by HPLC. Free doxorubicin administered by ILP resulted in a three-fold (100 microg) and 10-fold (400 microg) increase of the drug concentration in the tumor and normal lung tissue compared to IV administration. In contrast, ILP with Liporubicin resulted in a similar drug uptake in the tumor and lung tissue compared to IV injection. For both drug formulations and dosages, ILP resulted in a higher tumor to lung tissue drug ratio but also in a higher spatial heterogeneity of drug distribution within the lung compared to IV administration. ILP resulted in a higher tumor to lung tissue drug ratio and in a more heterogeneous drug distribution within the lung compared to IV drug administration.

Published
2009
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9. Ventilatory efficiency slope is associated with cardiopulmonary complications after thoracoscopic anatomical lung resection.

Author

Bédat B, Koliakos E, Demarchi MS, Perentes J, Licker MJ, Triponez F, Krueger T, Karenovics W, and Gonzalez M

Subjects
Carbon Dioxide adverse effects, Humans, Lung surgery, Postoperative Complications, Retrospective Studies, Thoracic Surgery, Video-Assisted adverse effects, Lung Neoplasms etiology, Lung Neoplasms surgery, Pneumonectomy adverse effects
Abstract

Objectives: The aim of this study was to identify whether steeper V.E/V. CO2 slope was associated with cardiopulmonary complications (CPC) after anatomical resection by video-assisted thoracic surgery. Long-term survival was analysed as secondary outcome., Methods: We reviewed the files of all consecutive patients who underwent pulmonary anatomical resections by video-assisted thoracic surgery between January 2010 and October 2020 at the Centre for Thoracic Surgery of Western Switzerland. Logistic regression was used to investigate the risk of CPC associated with the V.E/V.CO2 slope and other possible confounders. Survival was analysed with Kaplan-Meier curves. Risk factors associated with survival were analysed with a Cox proportional hazards model., Results: The V.E/V.CO2 slope data were available for 145 patients [F/M: 66/79; mean age (standard deviation): 65.8 (8.9)], which were included in the analysis. Patients underwent anatomical resection [lobectomy (71%) or segmentectomy (29%)] mainly for lung cancer (96%). CPC and all-cause 90-day mortality were 29% and 1%, respectively. The mean (standard deviation) percentage of the predicted V.O2peak was 70% (17). Maximum effort during cardiopulmonary exercise test was reached in only 31% of patients. The V.E/V.CO2 slope (standard deviation) was not different if the maximum effort was reached or not [39 (6) vs 37 (7), P = 0.21]. V.E/V.CO2 slope >35 was associated with an increased risk of CPC (odds ratio 2.9, 95% confidence interval 1.2, 7.2, P = 0.020). V.E/V.CO2 slope >35 was not associated with shorter survival censored for lung cancer-related death., Conclusions: V . E/V.CO2 slope >35 is significantly associated with postoperative CPC after anatomical resections by video-assisted thoracic surgery., Clinical Registration Number Cer-Vd (switzerland): Project ID: 2021-00620., (© The Author(s) 2022. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery.)

Published
2022
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