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Your search keyword '"Momotani E"' showing total 3 results
Start Over Author "Momotani E" Journal infection and immunity
3 results on '"Momotani E"'

1. Immunohistochemical distribution of ferritin, lactoferrin, and transferrin in granulomas of bovine paratuberculosis

Author

Momotani, E, Furugouri, K, Obara, Y, Miyata, Y, Ishikawa, Y, and Yoshino, T

Abstract

Granulomatous lesions of bovine paratuberculosis contained ferritin, lactoferrin, and a small amount of transferrin, as demonstrated by the immunohistochemical method. Macrophages in the normal bovine ileum did not contain lactoferrin and transferrin; however, ferritin was found in individual macrophages of Peyer's patches. These results may help elucidate the relationship between intracellular growth of Mycobacterium paratuberculosis and the presence of iron-binding proteins in the granulomas.

Published
1986
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2. Neutralization of interleukin-10 significantly enhances gamma interferon expression in peripheral blood by stimulation with Johnin purified protein derivative and by infection with Mycobacterium avium subsp. paratuberculosis in experimentally infected cattle with paratuberculosis.

Author

Buza JJ, Hikono H, Mori Y, Nagata R, Hirayama S, Aodon-geril, Bari AM, Shu Y, Tsuji NM, and Momotani E

Subjects
Animals, Cattle, Cattle Diseases microbiology, Leukocytes, Mononuclear immunology, Leukocytes, Mononuclear microbiology, Mycobacterium avium subsp. paratuberculosis pathogenicity, Neutralization Tests, Paratuberculosis microbiology, Up-Regulation, Cattle Diseases immunology, Interferon-gamma metabolism, Interleukin-10 immunology, Mycobacterium avium subsp. paratuberculosis immunology, Paratuberculosis immunology, Tuberculin immunology
Abstract

Monoclonal antibody neutralization of interleukin-10 (IL-10) increased Johnin purified protein derivative-induced whole-blood gamma interferon (IFN-gamma) secretion 23-fold and also increased IFN-gamma secretion ninefold following in vitro Mycobacterium avium subsp. paratuberculosis infection of peripheral blood mononuclear cells. These results demonstrate the suppressive effect of IL-10 on immune responses to M. avium subsp. paratuberculosis infection in cattle.

Published
2004
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3. Mycobacterium avium subsp. paratuberculosis infection causes suppression of RANTES, monocyte chemoattractant protein 1, and tumor necrosis factor alpha expression in peripheral blood of experimentally infected cattle.

Author

Buza JJ, Mori Y, Bari AM, Hikono H, Aodon-geril, Hirayama S, Shu Y, and Momotani E

Subjects
Animals, Cattle, Cattle Diseases immunology, Cattle Diseases microbiology, Paratuberculosis immunology, Paratuberculosis microbiology, Paratuberculosis physiopathology, Cattle Diseases physiopathology, Chemokine CCL2 blood, Chemokine CCL5 blood, Mycobacterium avium subsp. paratuberculosis pathogenicity, Tumor Necrosis Factor-alpha metabolism
Abstract

Blood from cattle with subclinical Mycobacterium avium subsp. paratuberculosis infection was stimulated with M. avium subsp. paratuberculosis antigens, and expression of interleukin-1beta (IL-1beta), tumor necrosis factor alpha (TNF-alpha), RANTES, monocyte chemoattractant protein 1 (MCP-1), and IL-8 was measured. Expression of TNF-alpha, RANTES, and MCP-1 was lower in infected than in uninfected cattle. The reduced response may weaken protective immunity and perpetuate infection.

Published
2003
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