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Diagnostic Criteria of Infection The diagnostic criteria of nosocomial infection adopted the Diagnostic Criteria of Nosocomial Infection (Trial) issued by the Ministry of Health in 2001.[11] The judgment criteria of MDRO infection adopted the unified consensus of international experts.[12] Calculation Formula MDRO detection rate = (number of MDRO strains/number of strains corresponding to the pathogen) × 100%; MDRO infection rate = (number of MDRO infections/number of specimens submitted for examination in the same period) × 100%; the proportion of MDRO infection = (number of MDRO infection cases/number of specific MDRO cases detected in the same period) × 100%; detection rate of MDRO infection = (number of MDRO infection cases/total number of inpatients in the same period) × 1000‰. The MDRO detection rate, MDRO infection rate, the proportion of MDRO infection, and detection rate of MDRO infection in different specimens were compared and analyzed. The detection rate of infection in sputum specimens ranked first (0.63 ‰), which was related to the highest proportion of respiratory tract infection in all infections. This study showed that the top three specimens in the proportion of MDRO infection were all sterile body fluids (blood, other sterile body fluids, and BALF), with the proportion of infection over 90%, which was much higher than that of other specimens (70.25-73.55%), implying the higher diagnostic and guiding values of sterile body fluids in clinical diagnosis and treatment. [Extracted from the article]