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Your search keyword '"Brönnimann D"' showing total 2 results
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2 results on '"Brönnimann D"'

1. Limbic encephalitis as a relapse of Whipple's disease with digestive involvement and spondylodiscitis.

Author

Brönnimann D, Vareil MO, Sibon I, Lagier JC, Lepidi H, Puges M, Haneche F, Raoult D, Desclaux A, Neau D, and Cazanave C

Subjects
Biopsy, Cerebrum pathology, Humans, Immunohistochemistry, Limbic Encephalitis microbiology, Limbic Encephalitis pathology, Male, Middle Aged, Polymerase Chain Reaction, Recurrence, Whipple Disease complications, Whipple Disease pathology, Limbic Encephalitis diagnosis, Tropheryma isolation & purification, Whipple Disease diagnosis
Abstract

Introduction: Many clinical manifestations can be related to Tropheryma whipplei infection., Case Report: We report a Tropheryma whipplei limbic encephalitis developed as a relapse of classical Whipple's disease., Discussion: This case is to the best of our knowledge the first proof of the effective brain-blood barrier crossing of both doxycycline and hydroxychloroquine as demonstrated by direct concentration monitoring on brain biopsy.

Published
2019
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2. Gamma delta T cell expansion in Whipple's disease with muscular granulomatous vasculitis.

Author

Brönnimann D, Vandenhende MA, and Viallard JF

Subjects
Anti-Bacterial Agents therapeutic use, Biomarkers, Humans, Male, Middle Aged, Symptom Assessment, Treatment Outcome, Whipple Disease diagnosis, Whipple Disease drug therapy, Granulomatosis with Polyangiitis complications, Lymphocyte Count, Receptors, Antigen, T-Cell, gamma-delta metabolism, T-Lymphocyte Subsets immunology, T-Lymphocyte Subsets metabolism, Whipple Disease complications, Whipple Disease immunology
Abstract

Whipple's disease usually presents as chronic joint pain followed by digestive manifestations. However, many different presentations have been described in the literature. We report here the first proven case of muscular vasculitis related to Whipple's disease, associated with an expansion of circulating activated γδ T lymphocytes.

Published
2018
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