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Background: Cerebral palsy is one of the common neurodevelopmental disorders seen in children and is associated with lifelong disability. Caregiver's health and well-being can be adversely affected because of long term delivery of care. It has been showed that family involved method is the best treatment strategy in needs of children with cerebral palsy. Aim of the study: To investigate the effect of caregiver education on quality of life and burden among caregivers of children with cerebral palsy. Methodology: The study used quasi experimental research design. 32 caregivers of children with cerebral palsy were included in the study. Caregiver education has been implemented to the participants. Quality of life and burden has been assessed by using WHOQOL-BREF and caregiver burden scale before and after one month of the caregiver education. Results: The results showed that there is a positive effect of caregiver education on quality of life and burden among caregivers of children with cerebral palsy. The WHOQOL-BREF shows a statistically significant results across 3 domains; physical, psychological and environmental whereas social component didn't show any significant change (p value >0.05). Caregiver burden scale also shows statistically significant results (p value <0.05) Conclusion: The caregiver education programme may be helpful for improving the quality of life and reducing the burden among caregivers of children with cerebral palsy. [ABSTRACT FROM AUTHOR]