Acidifiers are inorganic chemicals that potentially reduce gastric pH to improve nutrient utilization by suppressing invasion of pathogenic microorganism. One hundred Cobb 500™ broiler chicks were used in a 28-day trial of a completely randomized design to study the effects of acidifier supplementation on performance parameters, carcass characteristics and serum lipoprotein in commercial broiler. Birds were randomly distributed into five dietary treatment groups designated as T0, T1, T2, T3 and T4 where acidifier was supplemented at 0%, 0.1%, 0.2%, 0.3%, 0.4% in drinking water, respectively and each treatment was divided into two replicates having 20 birds per replicate. All birds had free access to ad-libitum feed and water. Results indicated that, weight gain decreased (P