1. A study of the association between Vitamin D deficiency and Dry Eye Syndrome (DES) in the Indian population.
- Author
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Jain, Nikita, Sharma, Pankaj, Chouhan, J, and Chouhan, J K
- Subjects
VITAMIN D deficiency ,DRY eye syndromes ,FILTER paper ,VITAMIN D ,CROSS-sectional method ,TEARS (Body fluid) ,FLUORESCENT dyes ,DISEASE complications - Abstract
Purpose: A study of the association between vitamin D deficiency and dry eye syndrome (DES) in the Indian population.Methods: This was a cross-sectional, hospital-based observational study. Sixty patients diagnosed with vitamin D deficiency (<20 ng/dl) who met the inclusion criteria were sent to the Eye OPD from the Endocrinology OPD (case) were compared to 60 subjects with normal vitamin D levels (≥20 ng/dl) who attended the Eye OPD (controls). The examination of the tear film was done using Whatman filter paper in Schirmer test I and Schirmer test I (with anesthesia). The tear film break-up time (TFBUT) was determined by slit-lamp examination using the fluorescein stain, and scoring using the ocular surface disease index (OSDI) was done.Results: A significant difference in the mean values of Schirmer I and Schirmer I test (with anesthesia) (P < 0.001) was seen between the case and control groups. A significant difference in the mean values of TFBUT (P < 0.001) and OSDI scores (P < 0.01) was also seen between the two groups.Conclusion: A positive association was found between vitamin D deficiency and dry eye on comparing the above parameters. [ABSTRACT FROM AUTHOR]- Published
- 2022
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