18 results on '"Archana, Singal"'
Search Results
2. Indurated dusky red swelling on the forearm of an infant: Tufted angioma
- Author
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Deepak Jakhar, Archana Singal, Ishmeet kaur, and Priya Pathak
- Subjects
Infant ,tufted angioma ,vascular tumor ,Dermatology ,RL1-803 - Abstract
Tufted angioma (TA) is a rare benign vascular tumor that may be congenital or acquired and generally presents as an asymptomatic or painful solitary erythematous to violaceous poorly defined plaque. Hyperhidrosis and hypertrichosis may be associated. The lesions have tendency to resolve spontaneously, in majority, within 2 years of disease onset. However, occurrence of Kassbach-Merritt phenomenon should be looked for. We present a case of 8-months-old infant with TA over the right forearm with classical clinical, histoptahological and immunohistochemistry features.
- Published
- 2019
- Full Text
- View/download PDF
3. Hypopigmented mycosis fungoides: Clinical, histological, and immunohistochemical remission induced by narrow-band ultraviolet B
- Author
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Kavita Bisherwal, Archana Singal, Deepika Pandhi, and Sonal Sharma
- Subjects
Hypopigmented mycosis fungoides ,mycosis fungoides ,narrow-band ultraviolet B ,phototherapy ,Dermatology ,RL1-803 - Abstract
Mycosis fungoides (MF) is the most common type of primary cutaneous lymphomas. Several clinical variants of MF have been described. Purely, hypopigmented variant of MF (HMF) is rare. Phototherapy, especially photochemotherapy (Psoralen and ultraviolet), is the most widely used method and is recommended as the first-line treatment for HMF. However, there are no standard guidelines for phototherapy as the disease is uncommon. We, hereby, report a 30-year-old woman with HMF in whom clinical, histopathological, and immunohistochemical remission was achieved following narrow-band ultraviolet B therapy.
- Published
- 2017
- Full Text
- View/download PDF
4. Solitary collagenoma of the labium majus: A rare occurrence
- Author
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Kavita Bisherwal, Archana Singal, Deepika Pandhi, and Vaibhav Girotra
- Subjects
Collagenoma ,isolated collagenoma ,labium majus ,vulvar collagenoma ,Dermatology ,RL1-803 - Abstract
Collagenomas are connective tissue nevi representing hamartomatous proliferation of collagen. Isolated collagenomas are of rare occurrence. They are sporadically acquired, and lesions are often localized to a single body region. We described a case of solitary collagenoma in a 23-year-old woman, confirmed on histopathology and special stains for collagen, involving an uncommon site such as labium majus. A high index of suspicion for a skin-colored circumscribed solitary growth and a low threshold for biopsy often help to arrive at a final diagnosis.
- Published
- 2017
- Full Text
- View/download PDF
5. Clinico-mycological study of dermatophyte toenail onychomycosis in New Delhi, India
- Author
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Pravesh Yadav, Archana Singal, Deepika Pandhi, and Shukla Das
- Subjects
Delhi ,dermatophyte ,epidemiology ,India ,onychomycosis ,toenail ,Dermatology ,RL1-803 - Abstract
Introduction: There is a constant need to define the epidemiological and mycological characteristics of onychomycosis (OM) for optimal management strategies. Objectives: To define the epidemiological and mycological characteristics of patients with dermatophyte toenail OM in a tertiary care hospital. Materials and Methods: Hundred consecutive patients of KOH and culture-positive dermatophyte toenail OM were subjected to detailed history, clinical examination and investigations. Results: Maximum number of patients (40%) belonged to 31-45 years age group and there was a male preponderance (M:F = 6.7:1). The mean duration of disease was 54 months. Thirty-three patients had fingernail involvement in addition to the toenail OM and 37% had co-existent cutaneous dermatophyte infection. Discoloration was the most common symptom (98%). Ninety-four (94%) patients had distal lateral subungual onychomycosis (DSLO) while two had superficial onychomycosis (SO) and only one had proximal superficial onychomycosis (PSO). Trichophyton interdigitale was the most common etiological agent (61%) followed by Trichophyton rubrum and Trichophyton verrucosum. Conclusions: Toenail OM is more common in males. DSLO was the most common clinical variant and T. interdigitale the most common etiological fungus responsible for toenail OM in our region. The importance of early diagnosis and treatment is highlighted as long-standing toenail OM predisposes to fingernail onychomycosis and recurrent tinea pedis.
- Published
- 2015
- Full Text
- View/download PDF
6. Leprosy scenario at a tertiary level hospital in Delhi: A 5-year retrospective study
- Author
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Namrata Chhabra, Chander Grover, Archana Singal, Sambit Nath Bhattacharya, and Ramandeep Kaur
- Subjects
Grade 2 deformity ,leprosy reactions ,multibacillary disease ,Dermatology ,RL1-803 - Abstract
Background: Leprosy has been officially eliminated from India since December, 2005; still, there are districts and blocks reporting high prevalence indicating ongoing transmission. The present study aimed at determining the current clinical profile of leprosy from a tertiary level hospital in Delhi. Materials and Methods: A retrospective, record-based study was carried out on patients diagnosed and registered in the leprosy clinic of a tertiary level teaching hospital in East district of Delhi (April 2007 to March 2012). Data regarding demographic details, clinical features, treatment started and complications was analyzed. Results: A total of 849 patients were registered over a 5-year period, with M: F ratio of 2.3:1. 9.3% were children (ͳ14 years). 54.3% patients were immigrants from adjoining states. Multibacillary leprosy was the most common clinical type (86.9%). Borderline tuberculoid leprosy was the most frequent morphologic type, seen in 56.3% followed by borderline-borderline (1.5%), borderline lepromatous (24.9%), lepromatous leprosy (8.1%), pure neuritic (8.1%), histoid and indeterminate leprosy (0.5% each). 37.4% patients presented in reaction (Type I in 30.4% cases and Type II in 7% cases). WHO grade II deformities were diagnosed in 37.9% with claw hand being the most common paralytic deformity (23.3% cases). Conclusion: Our study offers insight into the current status of the disease in an area of otherwise low prevalence. It is seen that despite statistical elimination, multibacillary disease, leprosy reactions and deformities are commonly seen as presenting manifestations, in contrast to national projected trends. Delhi′s unique demography with a high degree of migrant workers, presenting to our center (near border location) could be a possible contributing factor towards these aberrations. It highlights the need for continuation of targeted leprosy control activities and active case detection.
- Published
- 2015
- Full Text
- View/download PDF
7. Leprosy in post-elimination era in India: Difficult journey ahead
- Author
-
Archana Singal and Sidharth Sonthalia
- Subjects
Elimination ,epidemiological indicators ,leprosy ,prevalence rate ,Dermatology ,RL1-803 - Abstract
Leprosy is a chronic inflammatory disease of skin and peripheral nerves. Elimination of leprosy as a public health problem was reached at the global level in the year 2000 and by India on 31 st December, 2005. Thereafter, leprosy services in India have been integrated with General Health-Care System resulting in reduced focus and funds. Sustaining the gains made so far in controlling leprosy is a big challenge and there is no time for complacency. Pockets of high endemicity with prevalence rate of > 1 still exist in many states. Our data from a tertiary care center indicates poor epidemiological control and ongoing disease transmission. To combat this, dermatologists all over India should continue to play a central role in capacity building and training of undergraduate and post-graduate students, medical officers, and field workers.
- Published
- 2013
- Full Text
- View/download PDF
8. Imatinib mesylate-induced cutaneous rash masquerading as pityriasis rosea of Gilbert
- Author
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Prashant Verma, Archana Singal, and Sonal Sharma
- Subjects
Dermatology ,RL1-803 - Published
- 2014
- Full Text
- View/download PDF
9. Hypopigmented mycosis fungoides: Clinical, histological, and immunohistochemical remission induced by narrow-band ultraviolet B
- Author
-
Sonal Sharma, Deepika Pandhi, Kavita Bisherwal, and Archana Singal
- Subjects
narrow-band ultraviolet B ,Pathology ,medicine.medical_specialty ,Hypopigmented mycosis fungoides ,Case Report ,Dermatology ,Ultraviolet B therapy ,030207 dermatology & venereal diseases ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,medicine ,lcsh:Dermatology ,Psoralen ,Mycosis fungoides ,business.industry ,mycosis fungoides ,Ultraviolet b ,lcsh:RL1-803 ,medicine.disease ,Narrow band ,chemistry ,030220 oncology & carcinogenesis ,Immunohistochemistry ,business ,phototherapy - Abstract
Mycosis fungoides (MF) is the most common type of primary cutaneous lymphomas. Several clinical variants of MF have been described. Purely, hypopigmented variant of MF (HMF) is rare. Phototherapy, especially photochemotherapy (Psoralen and ultraviolet), is the most widely used method and is recommended as the first-line treatment for HMF. However, there are no standard guidelines for phototherapy as the disease is uncommon. We, hereby, report a 30-year-old woman with HMF in whom clinical, histopathological, and immunohistochemical remission was achieved following narrow-band ultraviolet B therapy.
- Published
- 2017
10. Pigmented palmo-plantar papules and plaques
- Author
-
Deepika Pandhi, Archana Singal, Sonal Sharma, and Sarla Agrawal
- Subjects
Dermatology ,RL1-803 - Published
- 2014
- Full Text
- View/download PDF
11. Nosocomial urinary tract aspergilloma in an immunocompetent host: An unusual occurrence
- Author
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Archana Singal, Chander Grover, Deepika Pandhi, Shukla Das, and Bhupinder Kumar Jain
- Subjects
Aspergillosis ,immuncompetent ,nosocomial ,urinary tract ,Dermatology ,RL1-803 - Abstract
Fungal infections of the urinary tract are usually encountered following prolonged antibiotic use, instrumentation and indwelling urinary catheters. Candida is the most frequent causative fungus. However, infections with Aspergillus flavus have been reported previously in immune-compromised hosts. We, hereby, report a 32-year-old immunocompetent man diagnosed to have urinary tract infection caused by Aspergillus flavus following instrumentation for the removal of a ureteric stone. The infection was symptomatic, associated with abdominal pain and subsequent passage of fungal masses per urethra. Patient was treated successfully with a prolonged course of broad spectrum antifungal agent itraconazole.
- Published
- 2013
- Full Text
- View/download PDF
12. Leprosy Scenario at a Tertiary Level Hospital in Delhi: A 5-year Retrospective Study
- Author
-
Chander Grover, Ramandeep Kaur, Namrata Chhabra, Sambit Nath Bhattacharya, and Archana Singal
- Subjects
Borderline tuberculoid leprosy ,leprosy reactions ,multibacillary disease ,Pediatrics ,medicine.medical_specialty ,Lepromatous leprosy ,High prevalence ,Transmission (medicine) ,business.industry ,Retrospective cohort study ,Dermatology ,Leprosy Round ,lcsh:RL1-803 ,medicine.disease ,Clinical type ,Surgery ,lcsh:Dermatology ,medicine ,Leprosy ,Tertiary level ,business ,Grade 2 deformity - Abstract
Background: Leprosy has been officially eliminated from India since December, 2005; still, there are districts and blocks reporting high prevalence indicating ongoing transmission. The present study aimed at determining the current clinical profile of leprosy from a tertiary level hospital in Delhi. Materials and Methods: A retrospective, record-based study was carried out on patients diagnosed and registered in the leprosy clinic of a tertiary level teaching hospital in East district of Delhi (April 2007 to March 2012). Data regarding demographic details, clinical features, treatment started and complications was analyzed. Results: A total of 849 patients were registered over a 5-year period, with M: F ratio of 2.3:1. 9.3% were children (ͳ14 years). 54.3% patients were immigrants from adjoining states. Multibacillary leprosy was the most common clinical type (86.9%). Borderline tuberculoid leprosy was the most frequent morphologic type, seen in 56.3% followed by borderline-borderline (1.5%), borderline lepromatous (24.9%), lepromatous leprosy (8.1%), pure neuritic (8.1%), histoid and indeterminate leprosy (0.5% each). 37.4% patients presented in reaction (Type I in 30.4% cases and Type II in 7% cases). WHO grade II deformities were diagnosed in 37.9% with claw hand being the most common paralytic deformity (23.3% cases). Conclusion: Our study offers insight into the current status of the disease in an area of otherwise low prevalence. It is seen that despite statistical elimination, multibacillary disease, leprosy reactions and deformities are commonly seen as presenting manifestations, in contrast to national projected trends. Delhi′s unique demography with a high degree of migrant workers, presenting to our center (near border location) could be a possible contributing factor towards these aberrations. It highlights the need for continuation of targeted leprosy control activities and active case detection.
- Published
- 2015
13. Bullous systemic lupus erythematosus
- Author
-
Chander Grover, Sonal Sharma, Ananta Khurana, and Archana Singal
- Subjects
Pathology ,medicine.medical_specialty ,Anemia ,Dermatology ,immunobullous diseases ,Dapsone ,medicine.disease_cause ,Neutrophilic Infiltrate ,Autoimmunity ,type VII collagen ,immune system diseases ,medicine ,skin and connective tissue diseases ,biology ,business.industry ,Antibody titer ,medicine.disease ,Type VII collagen ,E-Case Report ,biology.protein ,Histopathology ,Antibody ,business ,medicine.drug - Abstract
Bullous Systemic Lupus Erythematosus (BSLE) is a rare manifestation of Systemic Lupus Erythematosus (SLE), characterized histologically by subepidermal bullae with predominantly neutrophilic infiltrate and immunoglobulin (IgG, IgA, IgM) and C3 deposition at the basement membrane zone. Often associated is a heterogeneous profile of autoimmunity to components of type VII collagen. It needs to be differentiated from other subepidermal bullous diseases in view of potentially associated systemic manifestations of SLE. We report a 39-year-old lady who presented with an extensive vesicobullous eruption on face, neck, trunk, and mucosa. She was also found to have photosensitivity, significant anemia, and high antibody titers confirming SLE. Routine histopathology and immunoflorescence studies suggested BSLE and she responded favorably to dapsone. The importance of clinical and histopathological findings in confirming a diagnosis of BSLE along with the very encouraging response to dapsone therapy is highlighted.
- Published
- 2013
14. Nosocomial urinary tract aspergilloma in an immunocompetent host: an unusual occurrence
- Author
-
Bhupinder Kumar Jain, Archana Singal, Chander Grover, Shukla Das, and Deepika Pandhi
- Subjects
medicine.medical_specialty ,Abdominal pain ,Itraconazole ,immuncompetent ,Urinary system ,Aspergillus flavus ,Dermatology ,Aspergillosis ,Gastroenterology ,Internal medicine ,lcsh:Dermatology ,medicine ,urinary tract ,Ureteric Stone ,biology ,business.industry ,nosocomial ,lcsh:RL1-803 ,medicine.disease ,biology.organism_classification ,Surgery ,Urethra ,medicine.anatomical_structure ,E-Case Report ,medicine.symptom ,business ,Aspergilloma ,medicine.drug - Abstract
Fungal infections of the urinary tract are usually encountered following prolonged antibiotic use, instrumentation and indwelling urinary catheters. Candida is the most frequent causative fungus. However, infections with Aspergillus flavus have been reported previously in immune-compromised hosts. We, hereby, report a 32-year-old immunocompetent man diagnosed to have urinary tract infection caused by Aspergillus flavus following instrumentation for the removal of a ureteric stone. The infection was symptomatic, associated with abdominal pain and subsequent passage of fungal masses per urethra. Patient was treated successfully with a prolonged course of broad spectrum antifungal agent itraconazole.
- Published
- 2013
15. Clinico-mycological study of dermatophyte toenail onychomycosis in New Delhi, India
- Author
-
Deepika Pandhi, Pravesh Yadav, Shukla Das, and Archana Singal
- Subjects
medicine.medical_specialty ,India ,Physical examination ,Dermatology ,Trichophyton rubrum ,medicine.disease_cause ,Trichophyton verrucosum ,Epidemiology ,lcsh:Dermatology ,onychomycosis ,medicine ,Delhi ,skin and connective tissue diseases ,integumentary system ,medicine.diagnostic_test ,biology ,business.industry ,toenail ,dermatophyte ,lcsh:RL1-803 ,medicine.disease ,biology.organism_classification ,Trichophyton interdigitale ,Etiology ,Dermatophyte ,Original Article ,epidemiology ,New delhi ,business - Abstract
Introduction: There is a constant need to define the epidemiological and mycological characteristics of onychomycosis (OM) for optimal management strategies. Objectives: To define the epidemiological and mycological characteristics of patients with dermatophyte toenail OM in a tertiary care hospital. Materials and Methods: Hundred consecutive patients of KOH and culture-positive dermatophyte toenail OM were subjected to detailed history, clinical examination and investigations. Results: Maximum number of patients (40%) belonged to 31-45 years age group and there was a male preponderance (M:F = 6.7:1). The mean duration of disease was 54 months. Thirty-three patients had fingernail involvement in addition to the toenail OM and 37% had co-existent cutaneous dermatophyte infection. Discoloration was the most common symptom (98%). Ninety-four (94%) patients had distal lateral subungual onychomycosis (DSLO) while two had superficial onychomycosis (SO) and only one had proximal superficial onychomycosis (PSO). Trichophyton interdigitale was the most common etiological agent (61%) followed by Trichophyton rubrum and Trichophyton verrucosum. Conclusions: Toenail OM is more common in males. DSLO was the most common clinical variant and T. interdigitale the most common etiological fungus responsible for toenail OM in our region. The importance of early diagnosis and treatment is highlighted as long-standing toenail OM predisposes to fingernail onychomycosis and recurrent tinea pedis.
- Published
- 2015
16. Pigmented palmo-plantar papules and plaques
- Author
-
Archana Singal, Sonal Sharma, Deepika Pandhi, and Sarla Agrawal
- Subjects
medicine.medical_specialty ,business.industry ,E-IJD Quiz ,lcsh:Dermatology ,Medicine ,Dermatology ,lcsh:RL1-803 ,business - Published
- 2014
17. Imatinib mesylate-induced cutaneous rash masquerading as pityriasis rosea of Gilbert
- Author
-
Sonal Sharma, Archana Singal, and Prashant Verma
- Subjects
medicine.medical_specialty ,business.industry ,Dermatology ,lcsh:RL1-803 ,medicine.disease ,Rash ,Imatinib mesylate ,Correspondence ,Pityriasis rosea ,lcsh:Dermatology ,medicine ,medicine.symptom ,business - Published
- 2014
18. Leprosy in post-elimination era in India: Difficult journey ahead
- Author
-
Sidharth Sonthalia and Archana Singal
- Subjects
medicine.medical_specialty ,Elimination ,business.industry ,Public health ,Prevalence ,Capacity building ,Dermatology ,lcsh:RL1-803 ,prevalence rate ,Chronic inflammatory disease ,medicine.disease ,Tertiary care ,Surgery ,Special Article ,Family medicine ,Epidemiology ,lcsh:Dermatology ,medicine ,Leprosy ,business ,leprosy ,Disease transmission ,epidemiological indicators - Abstract
Leprosy is a chronic inflammatory disease of skin and peripheral nerves. Elimination of leprosy as a public health problem was reached at the global level in the year 2000 and by India on 31(st) December, 2005. Thereafter, leprosy services in India have been integrated with General Health-Care System resulting in reduced focus and funds. Sustaining the gains made so far in controlling leprosy is a big challenge and there is no time for complacency. Pockets of high endemicity with prevalence rate of > 1 still exist in many states. Our data from a tertiary care center indicates poor epidemiological control and ongoing disease transmission. To combat this, dermatologists all over India should continue to play a central role in capacity building and training of undergraduate and post-graduate students, medical officers, and field workers.
- Published
- 2013
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