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The article offers information on several appearances that could be observed in a clinical dermatology which could help in clinical diagnosis of skin diseases. Topics discussed include asbestos-like thick scales that is present in pityriasis amiantacea tine amiantacea, beefy red appearance that could mean vitamin B12 deficiency, and genital wart that presents a cauliflower-like fleshy growth.

A letter to the editor is presented regarding a 16-year-old girl with tiny hyperpigmented spots and was diagnosed with LEOPARD syndrome (LS), along with electrocardiographic (ECG) changes suggesting Wolff-Parkinson-White (WPW) syndrome.

The author discusses the importance of manuscript revision in the publication process to improve the paper's quality and suitability for publication and mentions several tips to revise to manuscript. Topics discussed include the types of revisions such as major, minor, and optimal, tips which include answering the question completely, politely, and with evidence, and the characteristics of the author to have a successful manuscript revision such as acceptance of criticism and perseverance.

There are 'n' number of names and terminologies in dermatology. The real and unreal names lead to lot of confusion to the residents and practitioners of dermatology. The word 'pseudo' means 'unreal', 'false' or 'fake', and it has deep roots in dermatology providing herculean task to differentiate and understand the real conditions/diseases/signs in dermatology. We have made an attempt to list and describe the pseudo and associated real conditions in dermatology. [ABSTRACT FROM AUTHOR]

Depigmentation therapy in vitiligo is an option in those with extensive vitiligo who have failed to respond to medical therapy and have obvious cosmetic disfigurement due to intervening patchy pigmented areas. Various aspects of this therapy such as the cost, treatment time, course, permanency of depigmentation, side effects, and the possibility of repigmentation should first be discussed with the patient. At present, there is no ideal depigmenting therapy available, but many agents in the market have been in use for many years. Monobenzyl ether of hydroquinone (MBEH) is the mainstay and Food and Drug Administration (FDA) approved in USA but takes many months to depigment and is associated with local side effects and risk of repigmentation. Other agents which are also used are 4-methoxy phenol and 88% phenol. Physical therapies for depigmentation include Q-switched ruby and alexandrite lasers and cryotherapy. Second-line agents which can be explored for depigmentation include imatinib mesylate, imiquimod, and diphencyprone. Many possible experimental agents are being explored like various phenol derivatives, melanoma vaccines, interferon gamma, busulfan, etc. A major lacuna still exists in this area and a lot more research is desirable to give satisfactory cosmesis to these patients with extensive vitiligo. [ABSTRACT FROM AUTHOR]

A letter to the editor is presented regarding the cases of a 48-year-old Indian woman and a 42-year-old man diagnosed with dermoscopic criteria following the use of skin lightening agents to treat melasma.

Dowling Degos disease is a rare, reticulate pigmentary disorder with variable phenotypic expression that manifests as hyperpigmented macules and reticulate pigmentary anomaly of the flexures. Many variants of this condition and its overlap with other reticulate pigmentary disorders have been reported in the literature. We present here two cases of DDD with follicular localization, both clinically and histologically. It was associated with ichthyosis vulgaris in one case. Follicular DDD is an uncommon variant of this evolving dermatosis. Our report supports the possible role for disordered follicular keratinisation in its pathogenesis. [ABSTRACT FROM AUTHOR]

Granulomatous cheilitis and granulomatous vulvitis are rare disorders characterized by painless swelling of lips and vulva, respectively. Histopathology of both conditions show non-caseating epithelioid cell granulomas in the dermis. Both disorders have been associated with Crohn's disease rarely. Occurrence of the two conditions in the same patient is extremely infrequent. We hereby report, the association of granulomatous cheilitis with granulomatous vulvitis in a 30-year-old female. [ABSTRACT FROM AUTHOR]

The article presents a case study of 2.5-year-old boy suffering from an asymptomatic skin lesion of his left buttock. The boy was diagnosed with tufted angioma (TA) or angioblastoma of Nakagawa. Included in suggested treatment options were compression therapy, surgical removal, cryosurgery and chemotherapy.

The author discusses the importance of impact factor to indicate the quality of journals developed by Irving H. Sher and Eugene Garfield in 1960. The author states that articles that were published in journals with high impact factor receives more points and positive attention when people search an academic benefits. He mentions several dermatology journals with high impact factors which include "Journal of Investigate Dermatology," "Indian Journal of Dermatology," and "Contact Dermatitits."