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Owing to the multifactorial pathological conditions management of obesity is a challenging problem. finding an effective and safe remedy is a huge area of interest for many scientists and healthcare professionals in the field of biomedicine. There is a traditional claim that fresh cow urine and its distillate have anti-obesity activity. The present study aimed to assess the bioactive fraction of distillated cow urine having anti-obesity potential. Distilled cow urine was extracted by liquid-liquid extraction method using different solvents. Distilled cow urine and all the fractions were assessed for the anti-obesity activity by analysing non-invasive parameters. The distilled cow urine and it's methanolic as well as butanolic fractions show significant anti-obesity potential. It has been found that body weight reduced without affecting food consumption. This effect was probably due to the reduction in dietary fat absorption by reducing the pancreatic lipase activity and enhancing its excretion in faeces. Further research is required to explore the exact mechanism of action. [ABSTRACT FROM AUTHOR]

The present study was undertaken to evaluate and compare antimicrobial, larvicidal and anthelmintic activity of Curcuma aromatica Salisb. cow urine extracts. The antimicrobial activity was performed using five microbial strains, v.i.z, Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Aspergillus niger and Aspergillus flavus; larvicidal activity was evaluated using 3rd and 4th instar stage larvaes, and anthelmintic activity using red earthworms (Lumbricus rubellus) with raw and photoactivated cow urine. Antimicrobial activity of photoactivated cow urine extract of C. aromatica (CAPUE) showed significant results when compared with raw cow urine extract of C. aromatic (CAUE). Larvicidal activity of CAPUE at a concentration of 25% V/V i.e. 40.2% V/V was found to show better mortality rate of larvae when compared with CAUE at a concentration of 25% v/v i.e. 45.2% V/V. Anthelmintic activity of CAPUE was found to show better paralysis and death time at a concentration of 10 μg/mL i.e 36.3 min for paralysis and 58.9 min for death when compared to CAUE i.e. 38.3 min paralysis rate at a concentration of 10 μg/mL and death rate is found 69.9 min at 10 μg/mL concentration. [ABSTRACT FROM AUTHOR]