1. Prognostic Evaluation of the Site of Invasion in Pathological Stage T3a Renal Cell Carcinoma.
- Author
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GU-SHUN LAI, JIAN-RI LI, SHIAN-SHIANG WANG, CHUAN-SHU CHEN, CHUN-KUANG YANG, SHENG-CHUN HUNG, CHEN-LI CHENG, YEN-CHUAN OU, and KUN-YUAN CHIU
- Subjects
PROGNOSTIC tests ,RENAL cell carcinoma ,PATHOLOGY ,NEPHRECTOMY ,CANCER prognosis - Abstract
Background/Aim: To investigate the prognostic values of fat invasion (FI) and renal vein invasion (RVI) in pT3a renal cell carcinoma (RCC), as single factors or concomitant presence. Patients and Methods: We retrospectively reviewed the data of 173 patients who underwent radical or partial nephrectomy for RCC in our Institution. Results: At a median follow-up time of 48 months, patients with RVI showed significantly increased risk of disease recurrence and worse cancer-specific survival (CSS) when compared to those with FI (p=0.007, p=0.022, respectively). Having combined RVI and FI did not show inferior prognosis compared to those with RVI only. In multivariable analysis, RVI was an independent factor for disease recurrence (HR=2.06, 95% CI=1.10- 3.87, p=0.024) and CSS (HR=2.46, 95% CI=1.01-6.0, p=0.048). Conclusion: For patients with T3a renal tumors, RVI was associated with inferior prognosis compared to those with FI. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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