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Introduction: Patients with pulmonary hypertension (PH) require repeat investigation to allow risk stratification and guide optimal therapy. These tests include CT and catheter studies utilising ionising radiation and contrast. Oxygen-enhanced magnetic resonance imaging (OE-MRI) is an alternative technique that provides measures related to regional ventilation, diffusion and perfusion and may provide novel biomarkers of PH severity. Aims: Assess correlation of OE-MRI measures with standard clinical measures of PH severity. Methods: Newly diagnosed group 1 or 4 PH patients underwent OE-MRI, with resultant measures compared with standard of care clinical outputs via Spearman’s correlation. Results: 12 patients were scanned (mean age 54.9±16.6 years old, mean pulmonary artery pressure 41.3±13.9mmHg). Significant correlation was seen between right ventricular (RV) end diastolic volume and median OE-MRI oxygen wash in time (WIT) (rs= 0.571, p= 0.048) and WIT interquartile range – a marker of spatial disease heterogeneity (rs= 0.857, p= 0.003). The WIT interquartile range also showed a moderate, negative association with RV ejection fraction (rs= -0.618, p=0.034). Interquartile range of native lung T1 relaxation time negatively correlated with TLCO (rs= -0.786, p= 0.021). Conclusions: Significant correlations have been demonstrated between OE-MRI measures of gas delivery and established markers of PH severity.

Abdominal symptoms are common in patients with AIDS. CT is frequently used to evaluate these symptoms.Findings on CT often non-diagnostic but nevertheless contribute towards patient management.Certain CT signs, together with a knowledge of the CD4 count, may help to indicate the likely diagnosis and enable early presumptive treatment.Post-treatment CT may be used to assess the resolution or progression of disease.CT is also useful in detecting intraabdominal complications arising from the treatment of AIDS.

Pulmonary manifestations of HIV disease are common.The pattern of disease has changed owing to a combination of factors. Plain radiography coupled with clinical assessment remains the starting point of investigation.CT is usually not required, except as a problem-solving tool.Whilst infection remains common, there are numerous non-infectious causes of acute chest symptoms.