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This paper addresses two fundamental problems: 1) learning discriminative model parameters and 2) avoiding over-fitting, which often occurs in regression-based classification tasks. We formulate these two problems in terms of relaxing both the strict binary label matrix and graph regularization term into more flexible forms so that the margins between different classes are enlarged as much as possible and the problem of over-fitting is avoided to some extent. This task is accomplished by the proposed double relaxed regression (DRR) method. The convex problem of DRR is solved efficiently with an iterative procedure. Extensive experiments on synthetic and real world image data sets demonstrate the effectiveness of the proposed method in terms of both classification accuracy and running time. [ABSTRACT FROM AUTHOR]