Social work professionals experience job-related stressors often associated with compromised mental health. In low-resource, conflict settings, such as the Occupied Palestinian Territories (OPT), structural and environmental obstacles pose additional challenges. This qualitative study identified stressors faced by 237 Palestinian social workers, current organizational strategies to reduce worker stress, and recommendations for new strategies. Content analysis identified 12 categories of stressors within five domains: role-related, interpersonal, organizational, societal, and miscellaneous. Current stress reduction efforts are perceived as ineffective, but numerous suggestions were offered for new initiatives. Implications for policy, practice, and research are discussed. Practice Points Palestinian public sector social workers face a litany of stressors at multiple levels, including role-related, interpersonal, organizational, and societal. In addition to the types of workplace stressors typically associated with social worker burnout and secondary traumatic stress, Palestinian social workers must also contend with stressors related to operating in a low-resource setting and under Israeli military occupation. While the Palestinian Ministry of Social Development is limited in its capacity to address many of the structural factors that contribute to worker stress, opportunities exist to promote worker well-being at an organizational level. [ABSTRACT FROM AUTHOR]