1. PGE 2 synthesis and signaling in malignant transformation and progression of human hepatocellular carcinoma
- Author
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Wenwen Liu, Aimin Huang, Jiasi Li, Jingfeng Liu, Xiaojie Ma, Yanbin Wu, Haili Cheng, and Shengbing Zang
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Prostaglandin E2 receptor ,medicine.medical_treatment ,Prostaglandin ,Biology ,Pathology and Forensic Medicine ,Malignant transformation ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Downregulation and upregulation ,Internal medicine ,medicine ,Receptor ,neoplasms ,medicine.disease ,digestive system diseases ,030104 developmental biology ,Endocrinology ,chemistry ,030220 oncology & carcinogenesis ,Hepatocellular carcinoma ,Cancer research ,lipids (amino acids, peptides, and proteins) ,Antagonism ,Prostaglandin E - Abstract
Prostaglandin E 2 (PGE2), which is the most abundant prostaglandin produced in hepatocellular carcinoma (HCC), may be involved in hepatocarcinogenesis. Here, the amount of PGE2 was significantly increased in HCC tissue and adjacent noncancerous tissues relative to normal liver tissue (P
- Published
- 2017
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