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Start Over Author "Natalie, Weeg" Journal human fertility
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1. The effect of maternal body mass index (BMI) and telomere function on in vitro fertilization (IVF) outcome: a preliminary cohort study

Author

Aliza Amiel, Tal Biron-Shental, Natalie Weeg, Einat Haikin, Amir Wiser, Anat Hershko Klement, and Adrian Shulman

Subjects
Infertility, Senescence, Pregnancy, In vitro fertilisation, business.industry, medicine.medical_treatment, Obstetrics and Gynecology, General Medicine, medicine.disease, Telomere, Andrology, Reproductive Medicine, Statistical significance, medicine, Mass index, business, Cohort study
Abstract

Telomeres are a specific base sequence of DNA, responsible for chromosome stability and DNA protection. We aimed to investigate the association between telomere systems and IVF outcomes according to patients' BMI. For all telomere characteristics, there was a distinct trend towards shorter telomeres and activation of telomere shortening compensatory mechanisms in the BMI group >25 kg/m2, reaching statistical significance for senescence only (r = 0.7, p value

Published
2019
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