1. Brain changes following four weeks of unimanual motor training: Evidence from fMRI‐guided diffusion MRI tractography
- Author
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Ross Cunnington, Stephen E. Rose, Lee B. Reid, Martin V. Sale, and Jason B. Mattingley
- Subjects
Adult ,Male ,Adolescent ,Pyramidal Tracts ,Functional Laterality ,050105 experimental psychology ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Fractional anisotropy ,Basal ganglia ,medicine ,Humans ,Learning ,0501 psychology and cognitive sciences ,Radiology, Nuclear Medicine and imaging ,Research Articles ,Brain Mapping ,Neuronal Plasticity ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,05 social sciences ,Brain ,Anatomy ,Magnetic Resonance Imaging ,White Matter ,Dorsolateral prefrontal cortex ,medicine.anatomical_structure ,Neurology ,Motor Skills ,Corticospinal tract ,Female ,Neurology (clinical) ,Functional magnetic resonance imaging ,Psychology ,030217 neurology & neurosurgery ,Diffusion MRI ,Motor cortex ,Tractography - Abstract
We have reported reliable changes in behavior, brain structure, and function in 24 healthy right‐handed adults who practiced a finger‐thumb opposition sequence task with their left hand for 10 min daily, over 4 weeks. Here, we extend these findings by using diffusion MRI to investigate white‐matter changes in the corticospinal tract, basal‐ganglia, and connections of the dorsolateral prefrontal cortex. Twenty‐three participant datasets were available with pre‐training and post‐training scans. Task performance improved in all participants (mean: 52.8%, SD: 20.0%; group P
- Published
- 2017
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