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Start Over Author "Mary Lee Vance" Journal hormone research
5 results on '"Mary Lee Vance"'

1. Growth Hormone and Nutrition

Author

Michael O. Thorner, Mary Lee Vance, and Mark L. Hartman

Subjects
Adult, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Biology, Growth hormone deficiency, Endocrinology, Hypothalamic Hormones, Internal medicine, medicine, Humans, Nutritional Physiological Phenomena, Secretion, Insulin-Like Growth Factor I, Growth factor, Proteins, Fasting, Lipid Metabolism, medicine.disease, Growth hormone secretion, Somatostatin, Growth Hormone, Carbohydrate Metabolism, Endocrine gland, Hormone
Abstract

The regulation of growth hormone (GH) secretion in humans is a complex process which comprises more than stimulation by GH-releasing hormone and suppression by somatostatin. Although these two hypothalamic hormones are the primary regulators of GH secretion, they most likely function as the final pathway through which numerous factors influence GH synthesis and secretion. Some of the modulators of GH secretion include neurotransmitters, circulating glucose, insulin-like growth factor I and gonadal steroid concentrations. Age, nutrition and body composition are also related to the amount and pattern of GH secretion in humans. The influence of nutritional status on GH secretion is becoming more clearly defined.

Published
1992

2. Foreword

Author

Mary Lee Vance and Francesco Chiarelli

Subjects
Endocrinology, Endocrinology, Diabetes and Metabolism
Published
2004

3. Therapeutic Agents Produced by Genetic Engineering: Quo Vadis? The Example of Growth Hormone and Its Releasing Factor

Author

G. Sassolas, P. de Pagter-Holthuizen, P. Bölen, C. Lassarre, F. Esch, J. Zapf, J C Job, P. Hossenlopp, D. Seurin, R.W. Furlanetto, P. Garry, M.O. Thorner, William S. Evans, M. Gourmelen, Jean-Marie Ketelslegers, S. Hardouin, Marcel Donnadieu, J.S. Sussenbach, M. Jansen, C.M. Hoogerbrugge, B. Claustrat, Georges Copinschi, F. Borson, Philippe Garnier, Max Rieu, S. Biot-Laporte, F.M.A. van Schaik, Louis E. Underwood, Jesús Argente, S.-Y. Ying, Anne Caufriez, Wylie Vale, J.P. Boissel, P. Dupin, P. Girard, A. Baird, Alan D. Rogol, E.R. Froesch, Matthew M. Rechler, M. Binoux, W.B. Wehrenberg, Marie-Christine Tonon, David R. Clemmons, Jean Rivier, J.L. Van den Brande, P. Chatelain, Robert M. Blizzard, J.F. Cara, Mary Lee Vance, S. C. van Buul-Offers, Marc Maes, C Liapi, N. Ling, Peter Nissley, Joseph D’Ercole, Danièle Evain Brion, and R. Cohen

Subjects
medicine.medical_specialty, Endocrinology, Endocrinology, Diabetes and Metabolism, Internal medicine, medicine, Biology, Growth hormone, Bioinformatics
Published
1986

4. Abstracts of Selected Free Communications

Author

Jesús Argente, Alan D. Rogol, J C Job, Max Rieu, J.S. Sussenbach, F. Esch, Joseph D’Ercole, S.-Y. Ying, P. de Pagter-Holthuizen, P. Bölen, P. Garry, Danièle Evain Brion, M. Gourmelen, G. Sassolas, William S. Evans, R. Cohen, S. Biot-Laporte, Georges Copinschi, D. Seurin, Jean-Marie Ketelslegers, W.B. Wehrenberg, Marie-Christine Tonon, M. Jansen, N. Ling, J. Zapf, David R. Clemmons, Jean Rivier, Peter Nissley, Marcel Donnadieu, S. Hardouin, E.R. Froesch, Matthew M. Rechler, P. Girard, F. Borson, Robert M. Blizzard, S. C. van Buul-Offers, F.M.A. van Schaik, M.O. Thorner, C Liapi, Wylie Vale, P. Dupin, Philippe Garnier, C.M. Hoogerbrugge, P. Hossenlopp, Louis E. Underwood, R.W. Furlanetto, C. Lassarre, J.F. Cara, Mary Lee Vance, J.L. Van den Brande, B. Claustrat, Anne Caufriez, J.P. Boissel, Marc Maes, P. Chatelain, A. Baird, and M. Binoux

Subjects
medicine.medical_specialty, Endocrinology, business.industry, Endocrinology, Diabetes and Metabolism, Internal medicine, medicine, Library science, business
Published
1986

5. Clinical studies with GHRH in man

Author

Mary Lee Vance, Robert M. Blizzard, Michael O. Thorner, William S. Evans, Wylie Vale, Jean Rivier, and Alan D. Rogol

Subjects
Adult, Male, endocrine system, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Dwarfism, Growth, Peptide hormone, Biology, Growth hormone, Growth Hormone-Releasing Hormone, Endocrinology, Pituitary adenoma, Internal medicine, Acromegaly, medicine, Humans, Child, Growth Disorders, Growth hormone–releasing hormone, medicine.disease, Somatomedin, medicine.anatomical_structure, Growth Hormone, Pancreas, hormones, hormone substitutes, and hormone antagonists
Abstract

GHRH was isolated from two GHRH-secreting pancreatic tumors which resulted in clinical acromegaly. Over 98% of acromegalic patients have a pituitary adenoma; however, acromegaly may occasionally result from ectopic or eutopic GHRH secretion. Administration of GHRH to normal adults stimulates growth hormone (GH) secretion; it may also stimulate GH release in some adults with GH deficiency in childhood and in a majority of GH-deficient children. Continuous infusion of GHRH to normal men stimulates GH secretion which augments naturally occurring GH pulses. GHRH is effective when administered subcutaneously and intranasally, but requires 30- and 300-fold higher doses, respectively. Intermittent subcutaneous GHRH therapy promotes acceleration of linear growth in GH-deficient children and appears promising as a treatment for these children.

Published
1986

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