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Start Over Author "Frouin, Eric" Journal histopathology
7 results on '"Frouin, Eric"'

2. Gene fusions in poroma, porocarcinoma and related adnexal skin tumours: An update

Author

Kervarrec, Thibault, primary, Pissaloux, Daniel, additional, Tirode, Franck, additional, de la Fouchardière, Arnaud, additional, Sohier, Pierre, additional, Frouin, Eric, additional, Hamard, Aymeric, additional, Houben, Roland, additional, Schrama, David, additional, Barlier, Anne, additional, Cribier, Bernard, additional, Battistella, Maxime, additional, and Macagno, Nicolas, additional

Published
2023
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3. Gene fusions in poroma, porocarcinoma and related adnexal skin tumours: An update.

Author

Kervarrec, Thibault, Pissaloux, Daniel, Tirode, Franck, de la Fouchardière, Arnaud, Sohier, Pierre, Frouin, Eric, Hamard, Aymeric, Houben, Roland, Schrama, David, Barlier, Anne, Cribier, Bernard, Battistella, Maxime, and Macagno, Nicolas

Subjects
YAP signaling proteins, SWEAT glands, TUMORS, DIFFERENTIAL diagnosis
Abstract

Poroma is a benign sweat gland tumour showing morphological features recapitulating the superficial portion of the eccrine sweat coil. A subset of poromas may transform into porocarcinoma, its malignant counterpart. Poroma and porocarcinoma are characterised by recurrent gene fusions involving YAP1, a transcriptional co‐activator, which is controlled by the Hippo signalling pathway. The fusion genes frequently involve MAML2 and NUTM1, which are also rearranged in other cutaneous and extracutaneous neoplasms. We aimed to review the clinical, morphological and molecular features of this category of adnexal neoplasms with a special focus upon emerging differential diagnoses, and discuss how their systematic molecular characterisation may contribute to a standardisation of diagnosis, more accurate classification and, ultimately, refinement of their prognosis and therapeutic modalities. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Recurrent PAK2 rearrangements in poroma with folliculo‐sebaceous differentiation

Author

Kervarrec, Thibault, primary, Pissaloux, Daniel, additional, Paindavoine, Sandrine, additional, Tirode, Franck, additional, Osio, Amélie, additional, Mourah, Samia, additional, Jouenne, Fanélie, additional, Sohier, Pierre, additional, Calonje, Eduardo, additional, Pekar, Agnes, additional, Luna, Evelyn Vanesa Erazo, additional, Goto, Keisuke, additional, Delalande, Flore, additional, Frouin, Eric, additional, Macagno, Nicolas, additional, Drouot, Françoise, additional, Faisan, Monique, additional, Cribier, Bernard, additional, Battistella, Maxime, additional, and de la Fouchardière, Arnaud, additional

Published
2023
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5. Distinct regulations driving YAP1 expression loss in poroma, porocarcinoma and RB1 ‐deficient skin carcinoma

Author

Kervarrec, Thibault, primary, Frouin, Eric, additional, Collin, Christine, additional, Tallet, Anne, additional, Tallegas, Matthias, additional, Pissaloux, Daniel, additional, Tirode, Franck, additional, Guyétant, Serge, additional, Samimi, Mahtab, additional, Gaboriaud, Pauline, additional, Touzé, Antoine, additional, Schrama, David, additional, Houben, Roland, additional, Tabareau‐Delalande, Flore, additional, Neuhart, Anne, additional, de la Fouchardière, Arnaud, additional, Osio, Amélie, additional, Cavelier–Balloy, Bénédicte, additional, Laurent‐Roussel, Sara, additional, Sohier, Pierre, additional, Cyprien, Tilmant, additional, Balme, Brigitte, additional, Belzung, Fanny, additional, Jullie, Marie‐Laure, additional, Cribier, Bernard, additional, Battistella, Maxime, additional, and Macagno, Nicolas, additional

Published
2023
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