Search

Your search keyword '"Jean Michel Vierfond"' showing total 4 results
Start Over Author "Jean Michel Vierfond" Journal heterocycles
4 results on '"Jean Michel Vierfond"'

1. A Synthesis of 2-Substituted Phenylbenzothiazoles

Author

Jean-Michel Vierfond, Yvette Mettey, Jean Michel Vierfond, and Sabine Michaud

Subjects
Pharmacology, Para position, chemistry.chemical_compound, Nitrile, chemistry, Bicyclic molecule, One pot reaction, Organic Chemistry, Medicinal chemistry, Analytical Chemistry, Sodium hydride
Abstract

A one-pot synthesis of 2-substituted phenylbenzothiazoles is achieved when 2-aminobenzenethiol is treated with an excess of sodium hydride and aromatic nitriles in THF. This method allows to obtain substituted products (F, CF 3 , Cl or OCH 3 ) in each ortho, meta and para position and plurisubstituted products

Published
1994

2. A Novel Synthetic Route to Cyanophenothiazines. First Example of Smiles Rearrangement from Halogenobenzonitriles

Author

Yvette Mettey and Jean-Michel Vierfond

Subjects
Pharmacology, Chemistry, Stereochemistry, Organic Chemistry, Disulfide bond, Smiles rearrangement, Mechanism (sociology), Analytical Chemistry
Abstract

The reaction of halogenobenzonitriles with 2-aminobenzenethiol gave, by a Smiles rearrangement 2-mercaptocyanodiphenylamines which are cyclised to cyanophenothiazines via a disulfide intermediate. A mechanism is proposed

Published
1993

3. A New Synthesis of 1-Hydroxyisoindoles

Author

Marcel Miocque, Jean-Michel Vierfond, A. Reynet, Christian Martin, and Y. Mettey

Subjects
Pharmacology, chemistry.chemical_compound, Bicyclic molecule, chemistry, Organic Chemistry, Liquid ammonia, Lactam, Combinatorial chemistry, Mechanism (sociology), Analytical Chemistry
Abstract

Heteroarylmethylation of halogenobenzonitriles in the presence of air (O 2 ) gives 1-hydroxy-3-oxo-1-aryl-1H,3H-isoindoles in liquid ammonia. A one-pot or two-step synthesis is described and a mechanism is proposed

Published
1992

4. Annelation of Quinoxaline by Sulfur Stabilized Carbanions

Author

Marcel Miocque, J. Mahuteau, L. Legendre, and Jean-Michel Vierfond

Subjects
Pharmacology, Annulation, Addition reaction, Bicyclic molecule, Organic Chemistry, chemistry.chemical_element, Sulfoxide, Sulfur, Analytical Chemistry, Sulfone, chemistry.chemical_compound, Quinoxaline, chemistry, Organic chemistry, Carbanion
Published
1989

Catalog

Books, media, physical & digital resources
See catalog results