1. Further data on adenosine deaminase polymorphism in pigs and evidence for a new allele
- Author
-
Daniele Bigi, R. K. Juneja, and B. Gahne
- Subjects
Male ,Erythrocytes ,Genotype ,Adenosine Deaminase ,Swine ,Nucleoside Deaminases ,Adenosine deaminase ,Polymorphism (computer science) ,Genetics ,medicine ,Leukocytes ,Animals ,Allele ,Allele frequency ,Alleles ,biology ,Isoelectric focusing ,General Medicine ,Breed ,Enzyme assay ,Red blood cell ,medicine.anatomical_structure ,Phenotype ,biology.protein ,Female ,Isoelectric Focusing ,Polymorphism, Restriction Fragment Length - Abstract
Evidence was provided for a new erythrocyte ADA allele (Aw) in the Swedish Landrace breed of pigs. The enzyme activity of Aw variant was considerably less than that of the previously reported erythrocyte ADA variants A and B. The mobility of the Aw variant was identical to that of the A variant, both by electrophoresis and by isoelectric focusing. The in vitro heat stability (at 56 degrees C) of the Aw variant was similar to that of A and B variants. The leucocyte ADA activity was normal in pigs with the erythrocyte ADA Aw variant. The frequencies of the erythrocyte ADA alleles, A, B, Aw, and O (silent allele) in four breeds of pigs in Sweden were: Landrace--0.51, 0.19, 0.11, 0.19; Large White--0.91, 0.03, 0.0, 0.06; Duroc--0.95, 0.05, 0.0, 0.0; Hampshire--0.12, 0.14, 0.0, 0.74.
- Published
- 1990