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Your search keyword '"Claudia Venturi"' showing total 2 results
Start Over Author "Claudia Venturi" Journal hematology reports
2 results on '"Claudia Venturi"'

1. Recurrent gastrointestinal hemorrhage in treatment with dasatinib in a patient showing SMAD4 mutation with acute lymphoblastic leukemia Philadelphia positive and juvenile polyposis hereditary hemorrhagic telangiectasia syndrome

Author

Chiara Sartor, Cristina Papayannidis, Maria Chiara Abbenante, Ilaria Iacobucci, Alessandro Broccoli, Claudia Venturi, Nicoletta Testoni, Anna Ferrari, and Giovanni Martinelli

Subjects
juvenile poyposis, hereditary hemorrhagic telangiectasia, acute lymphoblastic leukemia, SMAD4, Philadelphia chromosome, dasatinib, hemorrhage, Diseases of the blood and blood-forming organs, RC633-647.5
Abstract

We report a case of a patient affected by juvenile polyposis and hereditary hemorrhagic telangiectasia linked to a SMAD4 mutation who developed acute lymphoblastic leukemia positive for the Philadelphia chromosome translocation and with a complex karyotype. During the treatment with the tyrosine kinase inhibitor dasatinib the patient presented recurrent severe gastrointestinal hemorrhages linked to the genetic background and aggravated by thrombocytopenia.

Published
2013
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2. Recurrent Gastrointestinal Hemorrhage in Treatment with Dasatinib in a Patient Showing SMAD4 Mutation with Acute Lymphoblastic Leukemia Philadelphia Positive and Juvenile Polyposis Hereditary Hemorrhagic Telangiectasia Syndrome

Author

Giovanni Martinelli, Ilaria Iacobucci, Nicoletta Testoni, Alessandro Broccoli, Chiara Sartor, Maria Chiara Abbenante, Cristina Papayannidis, Claudia Venturi, Anna Maria Ferrari, Chiara Sartor, Cristina Papayannidi, Maria Chiara Abbenante, Ilaria Iacobucci, Alessandro Broccoli, Claudia Venturi, Nicoletta Testoni, Anna Ferrari, and Giovanni Martinelli

Subjects
Pathology, medicine.medical_specialty, juvenile poyposis, medicine.drug_class, Lymphoblastic Leukemia, Chromosomal translocation, Case Report, acute lymphoblastic leukemia, juvenile poyposis, hereditary hemorrhagic telangiectasia, acute lymphoblastic leukemia, SMAD4, Philadelphia chromosome, dasatinib, hemorrhage, Philadelphia chromosome, medicine.disease_cause, SMAD4, Tyrosine-kinase inhibitor, SMAD4 mutation, hemic and lymphatic diseases, Complex Karyotype, medicine, hereditary hemorrhagic telangiectasia, dasatinib, Telangiectasia, Mutation, lcsh:RC633-647.5, business.industry, lcsh:Diseases of the blood and blood-forming organs, Hematology, medicine.disease, Dasatinib, medicine.symptom, hemorrhage, business, medicine.drug
Abstract

We report a case of a patient affected by juvenile polyposis and hereditary hemorrhagic telangiectasia linked to a SMAD4 mutation who developed acute lymphoblastic leukemia positive for the Philadelphia chromosome translocation and with a complex karyotype. During the treatment with the tyrosine kinase inhibitor dasatinib the patient presented recurrent severe gastrointestinal hemorrhages linked to the genetic background and aggravated by thrombocytopenia.

Published
2013

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