1. More on the thrombocytopenia of the non-alcoholic fatty liver disease
- Author
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Juan Carlos Olivares-Gazca, Guillermo J. Ruiz-Argüelles, Yahveth Cantero-Fortiz, Mariana A. Méndez-Huerta, Ana Karen Nuñez-Cortes, and Juan Gerardo Orea-Martinez
- Subjects
Adult ,Male ,medicine.medical_specialty ,Cirrhosis ,Disease ,Overweight ,Gastroenterology ,Serology ,03 medical and health sciences ,0302 clinical medicine ,Non-alcoholic Fatty Liver Disease ,Internal medicine ,medicine ,Humans ,Platelet ,Aged ,business.industry ,Fatty liver ,nutritional and metabolic diseases ,Non alcoholic ,Hematology ,Middle Aged ,medicine.disease ,Thrombocytopenia ,digestive system diseases ,Liver ,030220 oncology & carcinogenesis ,Elasticity Imaging Techniques ,030211 gastroenterology & hepatology ,Female ,medicine.symptom ,Transient elastography ,business - Abstract
Background: Using only serologic determinations, we have previously found that thrombocytopenia presents in less than one half of patients with non-alcoholic fatty liver disease (NAFLD).Material and methods: Employing a more accurate method to define the presence of NAFLD, serologic determinations (Fibromax®) coupled with liver transient elastography (TE/Fibroscan®), we have prospectively studied a group of 211 individuals with a suspicion of a liver disease.Results: NAFLD was identified in 81 individuals. In 48 persons another causes of liver damage were identified and discarded from further analysis. A subset of 33 patients with NAFLD without liver fibrosis or cirrhosis was analyzed. In eight of them (24%), thrombocytopenia (less than 150 × 109/l platelets) was identified. The presence of thrombocytopenia in this subset of persons was associated with overweight, was usually mild, above 50 × 109/l, was not associated to mucocutaneous bleeding and did not require treatment.Conclusions: NAFLD shoul...
- Published
- 2016