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Your search keyword '"Margarita Sánchez-Beato"' showing total 5 results
Start Over Author "Margarita Sánchez-Beato" Journal hematological oncology
5 results on '"Margarita Sánchez-Beato"'

1. A GENE SIGNATURE TO PREDICT RISK OF TRANSFORMATION IN PATIENTS WITH FOLLICULAR LYMPHOMA

Author

Paloma Martín-Acosta, Francisco R García-Arroyo, Fina Climent, S. Sequero, Antonio Salar, N. Yanguas, F. de la Cruz, Julia González-Rincón, Sagrario Gómez, Marta Llanos, Margarita Sánchez-Beato, Lucia Pedrosa, Manuela Mollejo, Blanca Espinet, M. Dominguez, Santiago Mercadal, Mónica García-Cosío, Belen Navarro, Luis Colomo, Mariano Provencio, M A Piris, and Ismael Fernández-Miranda

Subjects
Cancer Research, Transformation (genetics), Oncology, Follicular lymphoma, medicine, Cancer research, In patient, Hematology, General Medicine, Biology, medicine.disease, Signature (topology), Gene
Published
2021

2. MUTATIONAL ANALYSIS OF THE DIFFERENT NODAL PERIPHERAL T‐CELL LYMPHOMA SUBCLASSES

Author

Ismael Fernández-Miranda, Paloma Martín-Acosta, Fina Climent, Ruth Alonso-Alonso, Juan F. García, Carmen Bárcena, Laura Tomás-Roca, Dolores Caballero, Socorro María Rodríguez-Pinilla, Mónica García-Cosío, M A Piris, Laura Cereceda, T. Villaescusa, Rebeca Manso, Raul Cordoba, M. Rodriguez, Margarita Sánchez-Beato, Manuela Mollejo, and Jennifer Borregón

Subjects
Mutational analysis, Cancer Research, Oncology, medicine, Cancer research, Hematology, General Medicine, Biology, medicine.disease, NODAL, Peripheral T-cell lymphoma
Published
2021

3. Transformed follicular lymphoma in the rituximab era: A report from the<scp>S</scp>panish<scp>L</scp>ymphoma<scp>O</scp>ncology<scp>G</scp>roup

Author

Julia González-Rincón, Mariano Provencio, Antonio Rueda, Marta Llanos, Miriam Mendez, Margarita Sánchez-Beato, José Gómez-Codina, Luis de la Cruz-Merino, Silvia Monsalvo, Pilar Sabin, Ana Royuela, Cristina Quero, Josep Gumá, Maria Torrente, and Delvys Rodriguez-Abreu

Subjects
Male, Oncology, Cancer Research, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Follicular lymphoma, Disease-Free Survival, 03 medical and health sciences, 0302 clinical medicine, International Prognostic Index, Risk Factors, Internal medicine, medicine, Humans, Cumulative incidence, Prospective Studies, Registries, Lymphoma, Follicular, Aged, Chemotherapy, business.industry, Hematology, General Medicine, Odds ratio, Middle Aged, medicine.disease, Lymphoma, Survival Rate, B symptoms, Spain, 030220 oncology & carcinogenesis, Female, Rituximab, medicine.symptom, business, Follow-Up Studies, 030215 immunology, medicine.drug
Abstract

Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) subtype. The histological transformation (HT) of FL is an event considered frequent in the natural history of this tumor. We studied the transformation rates, predictive factors, and treatment characteristics that may impact in the survival of patients with FL and HT. A total of 1074 patients diagnosed with FL were prospectively enrolled from 1990 to 2016 in a Spanish registry. Sixty-four HTs were recorded based on clinical criteria (55%) or histological confirmation (45%). The cumulative incidence rate of transformation at 5 years is 7.3%. The 5-year overall survival (OS) without HT was 85% (95% confidence interval [CI], 70%-90%) vs 66% (95% CI, 51%-76%; P = 0.0012) with HT. Factors associated with HT were elevated lactate dehydrogenase (LDH) (odds ratio [OR] 1.83), intermediate-high Follicular lymphoma international prognostic index (FLIPI) (OR 2.16-OR 3.21), B symptoms (OR 2.46), or Eastern Cooperative Oncology Group (ECOG) 1 (OR 2.35). Treatment options related to HT were "watch and wait" or no rituximab or anthracyclines initially. A 5-year OS for patients treated with chemotherapy before HT was 55% (95% CI, 38%-69%) versus 81% (95% CI, 53%-93%; P = 0.009) for those who had not received it. The HT rate has decreased after the introduction of rituximab, as has been previously described. The timing of this treatment had an impact on the survival of these patients.

Published
2019

4. A PTCL GENE SIGNATURE CAPTURING STROMAL AND NEOPLASTIC DATA STRATIFIES PTCL/NOS AND AITL INTO DIFFERENT GROUPS WITH VARIABLE SURVIVAL PROBABILITY

Author

Paloma Martín-Acosta, T. Villaescusa, Rafael Feito Alonso, Carmen Bárcena, Fina Climent, Ismael Fernández-Miranda, M. Rodriguez, Socorro María Rodríguez-Pinilla, Manuela Mollejo, L. Kessler, M A Piris, Mónica García-Cosío, C. Scholz, Juan F. García, Dolores Caballero, Antonio Gualberto, Laura Cereceda, Margarita Sánchez-Beato, Rufino Mondejar, and Raul Cordoba

Subjects
Cancer Research, Stromal cell, Oncology, Variable survival, Cancer research, Hematology, General Medicine, Gene signature, Biology, Ptcl nos
Published
2019

5. DIFFUSE LARGE B-CELL LYMPHOMA SURVIVAL PROGNOSTICATION, A COMPARATIVE ANALYSIS OF CELL OF ORIGIN VS. MYC/BCL2 EXPRESSION

Author

Rufino Mondejar, Francisca I. Camacho, Mónica García-Cosío, Paloma Martín-Acosta, Y. Castro, Ismael Fernández-Miranda, Gabriel Olmedilla, M. Fraga, Antonio García Sánchez, Cristina Quero, Marta Llanos, Fina Climent, Miguel A. Piris, E. Bacalari, Lucia Pedrosa, R. Alonso, Sagrario Gómez, Miguel Piris-Villaespesa, Margarita Sánchez-Beato, R. Cordoba, Juan F. García, Carmen Bárcena, M. Rodriguez, J. Capote, Socorro María Rodríguez-Pinilla, Mariano Provencio, Manuela Mollejo, Empar Mayordomo, and L. Cereceda

Subjects
Cancer Research, Oncology, Cell of origin, Cancer research, medicine, Hematology, General Medicine, Biology, medicine.disease, Diffuse large B-cell lymphoma
Published
2019

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