10 results on '"Philippe Gaulard"'
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2. S238: CLONAL ARCHITECTURE OF RELAPSED OR REFRACTORY ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA: AN ANCILLARY STUDY OF THE ORACLE TRIAL, A LYSA STUDY
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Romain Loyaux, Nouhoum Sako, Violaine Tran Quang, Emmanuel Bachy, Franck Morschhauser, Guillaume Cartron, Remy Gressin, Nicolas Daguindau, Steven Le Gouill, Cyrielle Robe, Elisa Boudali, Marie-Helene Delfau-Larue, Jehan Dupuis, Laurence De Leval, Philippe Gaulard, Francois Lemonnier, and Ivan Sloma
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Diseases of the blood and blood-forming organs ,RC633-647.5 - Published
- 2023
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3. P1224: PATIENT-DERIVED XENOGRAFT (PDX) IS A USEFUL TOOL FOR EVALUATING 5-AZACYTIDINE SENSITIVITY IN TFH LYMPHOMAS
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Gamze Tari, Nouhoum Sako, Cyrielle Robe, Marie-Helene Delfau-Larue, Nicolas Ortonne, Philippe Gaulard, and Francois Lemonnier
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Diseases of the blood and blood-forming organs ,RC633-647.5 - Published
- 2023
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4. Genetic and Microenvironment Features Do Not Distinguish Follicular Lymphoma Patients Requiring Immediate or Deferred Treatment
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Wendy B. C. Stevens, G. Tjitske Los-de Vries, Carole Langois-Jacques, Andrew J. Clear, Phylicia Stathi, Birgitta Sander, Andreas Rosenwald, Maria Calaminici, Eva Hoster, Wolfgang Hiddemann, Philippe Gaulard, Gilles Salles, Wolfram Klapper, Luc Xerri, Catherine Burton, Reuben M. Tooze, Alexandra G. Smith, Christian Buske, David W. Scott, Yasodha Natkunam, Ranjana Advani, Laurie H. Sehn, John Raemaekers, John Gribben, Sandra Lockmer, Eva Kimby, Marie José Kersten, Delphine Maucort-Boulch, Bauke Ylstra, Erik van Dijk, and Daphne de Jong
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Diseases of the blood and blood-forming organs ,RC633-647.5 - Published
- 2023
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5. The EHA Research Roadmap: Malignant Lymphoid Diseases
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Martin Dreyling, Marc André, Nicola Gökbuget, Hervé Tilly, Mats Jerkeman, John Gribben, Andrés Ferreri, Pierre Morel, Stephan Stilgenbauer, Christopher Fox, José Maria Ribera, Sonja Zweegman, Igor Aurer, Csaba Bödör, Birgit Burkhardt, Christian Buske, Maria Dollores Caballero, Elias Campo, Bjoern Chapuy, Andrew Davies, Laurence de Leval, Jeanette Doorduijn, Massimo Federico, Philippe Gaulard, Francesca Gay, Paolo Ghia, Kirsten Grønbæk, Hartmut Goldschmidt, Marie-Jose Kersten, Barbara Kiesewetter, Judith Landman-Parker, Steven Le Gouill, Georg Lenz, Sirpa Leppä, Armando Lopez-Guillermo, Elizabeth Macintyre, Maria Victoria Mateos Mantega, Philippe Moreau, Carol Moreno, Bertrand Nadel, Jessica Okosun, Roger Owen, Sarka Pospisilova, Christiane Pott, Tadeusz Robak, Michelle Spina, Kostas Stamatopoulos, Jan Stary, Karin Tarte, Allessandra Tedeschi, Catherine Thieblemont, Ralf Ulrich Trappe, Lorenz H. Trümper, and Gilles Salles
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Diseases of the blood and blood-forming organs ,RC633-647.5 - Published
- 2022
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6. Prolonged Remissions After Nivolumab Plus Gemcitabine/Oxaliplatin in Relapsed/Refractory T-cell Lymphoma
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Roch Houot, Viola Poeschel, Bettina Altmann, Stephanie Angel, Lorenz Thurner, Thomas Illmer, Marc Andre, Martin Dreyling, Hervé Maisonneuve, Hervé Tilly, Stephanie Mayer, Olivier Casasnovas, Steven Le Gouill, Fritz Offner, Guillaume Cartron, Andrea Kerkhoff, Thomas Weber, Joerg Hoffmann, Marita Ziepert, Wolfram Klapper, Emmanuel Itti, Dirk Hellwig, Giorgi Natchkebia, Laurence de Leval, Andreas Rosenwald, Corinne Haioun, Laurent Dercle, Philippe Gaulard, and Gerhard Held
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Diseases of the blood and blood-forming organs ,RC633-647.5 - Published
- 2022
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7. Controversies in the Treatment of Peripheral T-cell Lymphoma
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Emmanuel Bachy, Alessandro Broccoli, Claire Dearden, Laurence de Leval, Philippe Gaulard, Raphael Koch, Franck Morschhauser, Lorenz Trümper, and Pier Luigi Zinzani
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Diseases of the blood and blood-forming organs ,RC633-647.5 - Abstract
Abstract. Peripheral T-cell lymphomas are a heterogeneous group of rare diseases with an aggressive behavior and dismal prognosis. Their classification is complex and still evolving, and several biomolecular markers now help refine the prognosis of specific disease entities, although still have limited impact in tailoring the treatment. First-line treatment strategies can cure only a minority of patients and relapsed-refractory disease still represents the major cause of failure. Frontline autologous transplantation may have an impact in the consolidation of response; however, its role is still questioned as far as complete responses obtained after induction chemotherapy are concerned. Newer drugs are now being evaluated in clinical trials, but effective salvage strategies for those who experience treatment failures are lacking. Here we review and discuss the most controversial aspects of diagnosis and treatment of peripheral T-cell lymphomas.
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- 2020
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8. The Need for a Consensus Next-generation Sequencing Panel for Mature Lymphoid Malignancies
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Pierre Sujobert, Yannick Le Bris, Laurence de Leval, Audrey Gros, Jean Philippe Merlio, Cedric Pastoret, Sarah Huet, Clémentine Sarkozy, Frédéric Davi, Mary Callanan, Catherine Thieblemont, David Sibon, Vahid Asnafi, Claude Preudhomme, Philippe Gaulard, Fabrice Jardin, Gilles Salles, and Elizabeth Macintyre
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Diseases of the blood and blood-forming organs ,RC633-647.5 - Published
- 2019
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9. Controversies in the Treatment of Peripheral T-cell Lymphoma
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Philippe Gaulard, Pier Luigi Zinzani, Alessandro Broccoli, Franck Morschhauser, Claire Dearden, Emmanuel Bachy, Raphael Koch, Laurence de Leval, Lorenz Trümper, Bachy, E, Broccoli, A, Dearden, C, de Leval, L, Gaulard, P, Koch, R, Morschhauser, F, Trumper, L, and Zinzani, PL
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Oncology ,medicine.medical_specialty ,Controversy ,MEDLINE ,Disease ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Autologous transplantation ,030304 developmental biology ,0303 health sciences ,Heterogeneous group ,business.industry ,Peripheral T-cell Lymphoma, treatment, autologous transplantation, induction chemotherapy ,lcsh:RC633-647.5 ,Induction chemotherapy ,Hematology ,lcsh:Diseases of the blood and blood-forming organs ,medicine.disease ,Peripheral T-cell lymphoma ,3. Good health ,Clinical trial ,030220 oncology & carcinogenesis ,Treatment strategy ,business - Abstract
Peripheral T-cell lymphomas are a heterogeneous group of rare diseases with an aggressive behavior and dismal prognosis. Their classification is complex and still evolving, and several biomolecular markers now help refine the prognosis of specific disease entities, although still have limited impact in tailoring the treatment. First-line treatment strategies can cure only a minority of patients and relapsed-refractory disease still represents the major cause of failure. Frontline autologous transplantation may have an impact in the consolidation of response; however, its role is still questioned as far as complete responses obtained after induction chemotherapy are concerned. Newer drugs are now being evaluated in clinical trials, but effective salvage strategies for those who experience treatment failures are lacking. Here we review and discuss the most controversial aspects of diagnosis and treatment of peripheral T-cell lymphomas.
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- 2020
10. The Need for a Consensus Next-generation Sequencing Panel for Mature Lymphoid Malignancies
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Gilles Salles, Catherine Thieblemont, Vahid Asnafi, Yannick Le Bris, Elizabeth Macintyre, Audrey Gros, Pierre Sujobert, David Sibon, Sarah Huet, Cedric Pastoret, Jean-Philippe Merlio, Clémentine Sarkozy, Fabrice Jardin, Laurence de Leval, Claude Preudhomme, Frederic Davi, Philippe Gaulard, Mary Callanan, Jonchère, Laurent, Hospices Civils de Lyon (HCL), Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche en Cancérologie et Immunologie Nantes-Angers (CRCINA), Université d'Angers (UA)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre hospitalier universitaire de Nantes (CHU Nantes), Division de cardiologie [CHU Vaudois] (CHUV), Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV), Physiopathologie du cancer du foie, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM), Microenvironment, Cell Differentiation, Immunology and Cancer (MICMAC), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon, CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB), Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Université Paris Diderot - Paris 7 (UPD7), Université Paris Descartes - Paris 5 (UPD5), Imagine - Institut des maladies génétiques (IMAGINE - U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 (JPArc), Université Lille Nord de France (COMUE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, CHU Henri Mondor, Université Paris-Est Marne-la-Vallée (UPEM), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Génomique et Médecine Personnalisée du Cancer et des Maladies Neuropsychiatriques (GPMCND), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Henri Mondor [Créteil], Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Centre National de la Recherche Scientifique (CNRS)-Université d'Angers (UA), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U1172 Inserm - U837 (JPArc), and Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Lille Nord de France (COMUE)-Université de Lille
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0303 health sciences ,lcsh:RC633-647.5 ,business.industry ,MEDLINE ,[SDV.CAN]Life Sciences [q-bio]/Cancer ,lcsh:Diseases of the blood and blood-forming organs ,Computational biology ,Hematology ,DNA sequencing ,03 medical and health sciences ,Text mining ,0302 clinical medicine ,[SDV.CAN] Life Sciences [q-bio]/Cancer ,030220 oncology & carcinogenesis ,Perspective ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,Medicine ,business ,ComputingMilieux_MISCELLANEOUS ,030304 developmental biology ,030215 immunology - Abstract
International audience; Supplemental Digital Content is available in the text.
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- 2018
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