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1. Heart rate variability and stroke or systemic embolism in patients with atrial fibrillation

Author

Aeschbacher, Stefanie, Bhend, Katalin, Blum, Steffen, Bonati, Leo H., Carmine, Désirée, Conen, David, Eken, Ceylan, Fischer, Urs, Girroy, Corinne, Hennings, Elisa, Krisai, Philipp, Kühne, Michael, Mäder, Nina, Meyer-Zürn, Christine, Meyre, Pascal B., Monsch, Andreas U., Mosher, Luke, Müller, Christian, Osswald, Stefan, Paladini, Rebecca E., Peter, Raffaele, Schweigler, Adrian, Sticherling, Christian, Szucs, Thomas, Völlmin, Gian, Aujesky, Drahomir, Fuhrer, Juerg, Roten, Laurent, Jung, Simon, Mattle, Heinrich, Netzer, Seraina, Adam, Luise, Aubert, Carole Elodie, Feller, Martin, Loewe, Axel, Moutzouri, Elisavet, Schneider, Claudio, Flückiger, Tanja, Groen, Cindy, Ehrsam, Lukas, Hellrigl, Sven, Nuoffer, Alexandra, Rakovic, Damiana, Schwab, Nathalie, Wenger, Rylana, Zarrabi Saffari, Tu Hanh, Rodondi, Nicolas, Reichlin, Tobias, Beynon, Christopher, Dillier, Roger, Deubelbeiss, Michèle, Eberli, Franz, Franzini, Christine, Juchli, Isabel, Liedtke, Claudia, Murugiah, Samira, Nadler, Jacqueline, Obst, Thayze, Roth, Jasmin, Schlomowitsch, Fiona, Schneider, Xiaoye, Studerus, Katrin, Tynan, Noreen, Weishaupt, Dominik, Müller, Andreas, Friedli, Corinne, Kuest, Silke, Scheuch, Karin, Hischier, Denise, Bonetti, Nicole, Grau, Alexandra, Villinger, Jonas, Laube, Eva, Baumgartner, Philipp, Filipovic, Mark, Frick, Marcel, Montrasio, Giulia, Leuenberger, Stefanie, Rutz, Franziska, Beer, Jürg-Hans, Auricchio, Angelo, Anesini, Adriana, Camporini, Cristina, Caputo, Maria Luce, Peronaci, Rebecca, Regoli, Francois, Ronchi, Martina, Conte, Giulio, Brenner, Roman, Altmann, David, Fink, Karin, Gemperle, Michaela, Ammann, Peter, Firmann, Mathieu, Foucras, Sandrine, Rime, Martine, Hayoz, Daniel, Berte, Benjamin, Bühler, Kathrin, Justi, Virgina, Kellner-Weldon, Frauke, Koch, Melanie, Mehmann, Brigitta, Meier, Sonja, Roth, Myriam, Ruckli-Kaeppeli, Andrea, Russi, Ian, Schmidt, Kai, Young, Mabelle, Kobza, Richard, Rigamonti, Elia, Cereda, Carlo, Cianfoni, Alessandro, De Perna, Maria Luisa, Frangi-Kultalahti, Jane, Mayer Melchiorre, Patrizia Assunta, Pin, Anica, Terrot, Tatiana, Vicari, Luisa, Moschovitis, Giorgio, Ehret, Georg, Gallet, Hervé, Guillermet, Elise, Lazeyras, Francois, Lovblad, Karl-Olof, Perret, Patrick, Tavel, Philippe, Teres, Cheryl, Shah, Dipen, Lauriers, Nathalie, Méan, Marie, Salzmann, Sandrine, Schläpfer, Jürg, Porretta, Alessandra Pia, Grêt, Andrea, Novak, Jan, Vitelli, Sandra, Stephan, Frank-Peter, Gallino, Augusto, Di Valentino, Marcello, Aebersold, Helena, Foster, Fabienne, Schwenkglenks, Matthias, Düring, Marco, Sinnecker, Tim, Altermatt, Anna, Amann, Michael, Huber, Petra, Hürbin, Manuel, Ruberte, Esther, Thöni, Alain, Würfel, Jens, Zuber, Vanessa, Coslovsky (Head), Michael, Neuschwander, Pia, Simon, Patrick, Wunderlin, Olivia, Schmid, Ramun, Baumann, Christian, Hämmerle, Peter, Schlageter, Vincent, Coslovsky, Michael, Coduri, Federica, Blum, Manuel R., Stauber, Annina, Beer, Jürg, and Zuern, Christine S.

Published
2024
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3. Machine learning–derived major adverse event prediction of patients undergoing transvenous lead extraction: Using the ESC EHRA EORP European lead extraction ConTRolled ELECTRa registry

Author

Mehta, Vishal S., O’Brien, Hugh, Elliott, Mark K., Wijesuriya, Nadeev, Auricchio, Angelo, Ayis, Salma, Blomstrom-Lundqvist, Carina, Bongiorni, Maria Grazia, Butter, Christian, Deharo, Jean-Claude, Gould, Justin, Kennergren, Charles, Kuck, Karl-Heinz, Kutarski, Andrzej, Leclercq, Christophe, Maggioni, Aldo P., Sidhu, Baldeep S., Wong, Tom, Niederer, Steven, and Rinaldi, Christopher A.

Published
2022
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4. Implantation of cardiac electronic devices in active COVID-19 patients: Results from an international survey

Author

Tovia-Brodie, Oholi, Rav Acha, Moshe, Belhassen, Bernard, Gasperetti, Alessio, Schiavone, Marco, Forleo, Giovanni Battista, Guevara-Valdivia, Milton E., Ruiz, David Valdeolivar, Lellouche, Nicolas, Hamon, David, Castagno, Davide, Bellettini, Matteo, De Ferrari, Gaetano M., Laredo, Mikael, Carvès, Jean-Baptiste, Ignatiuk, Barbara, Pasquetto, Giampaolo, De Filippo, Paolo, Malanchini, Giovanni, Pavri, Behzad B., Raphael, Craig, Rivetti, Luigi, Mantovan, Roberto, Chinitz, Jason, Harding, Melissa, Boriani, Giuseppe, Casali, Edoardo, Wan, Elaine Y., Biviano, Angelo, Macias, Carlos, Havranek, Stepan, Lazzerini, Pietro Enea, Canu, Antonio M., Zardini, Marco, Conte, Giulio, Cano, Óscar, Casella, Michela, Rudic, Boris, Omelchenko, Alexander, Mathuria, Nilesh, Upadhyay, Gaurav A., Danon, Asaf, Schwartz, Arie Lorin, Maury, Philippe, Nakahara, Shiro, Goldenberg, Gustavo, Schaerli, Nicolas, Bereza, Sergiy, Auricchio, Angelo, Glikson, Michael, and Michowitz, Yoav

Published
2022
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6. Insulin-like growth factor-binding protein 7 and risk of congestive heart failure hospitalization in patients with atrial fibrillation

Author

Aeschbacher, Stefanie, Auberson, Chloé, Blum, Steffen, Bonati, Leo, Ceylan, Selinda, Conen, David, Doerpfeld, Simone, Eken, Ceylan, Girod, Marc, Hämmerle, Peter, Krisai, Philipp, Kühne, Michael, Meyer-Zürn, Christine, Meyre, Pascal, Monsch, Andreas U., Müller, Christian, Osswald, Stefan, Springer, Anne, Sticherling, Christian, Szucs, Thomas, Voellmin, Gian, Zwimpfer, Leon, Aujesky, Drahomir, Fischer, Urs, Fuhrer, Juerg, Roten, Laurent, Jung, Simon, Mattle, Heinrich, Adam, Luise, Aubert, Carole Elodie, Feller, Martin, Loewe, Axel, Moutzouri, Elisavet, Schneider, Claudio, Flückiger, Tanja, Groen, Cindy, Ehrsam, Lukas, Hellrigl, Sven, Nuoffer, Alexandra, Rakovic, Damiana, Schwab, Nathalie, Wenger, Rylana, Rodondi, Nicolas, Beynon, Christopher, Dillier, Roger, Deubelbeiss, Michèle, Eberli, Franz, Franzini, Christine, Juchli, Isabel, Liedtke, Claudia, Nadler, Jacqueline, Obst, Thayze, Roth, Jasmin, Schlomowitsch, Fiona, Schneider, Xiaoye, Studerus, Katrin, Tynan, Noreen, Weishaupt, Dominik, Müller, Andreas, Fontana, Simone, Kuest, Silke, Scheuch, Karin, Hischier, Denise, Bonetti, Nicole, Grau, Alexandra, Villinger, Jonas, Laube, Eva, Baumgartner, Philipp, Filipovic, Mark, Frick, Marcel, Montrasio, Giulia, Leuenberger, Stefanie, Rutz, Franziska, Beer, Jürg-Hans, Auricchio, Angelo, Anesini, Adriana, Camporini, Cristina, Conte, Giulio, Caputo, Maria Luce, Regoli, Francois, Moccetti, Tiziano, Brenner, Roman, Altmann, David, Gemperle, Michaela, Ammann, Peter, Firmann, Mathieu, Foucras, Sandrine, Rime, Martine, Hayoz, Daniel, Berte, Benjamin, Justi, Virgina, Kellner-Weldon, Frauke, Mehmann, Brigitta, Meier, Sonja, Roth, Myriam, Ruckli-Kaeppeli, Andrea, Russi, Ian, Schmidt, Kai, Young, Mabelle, Zbinden, Melanie, Kobza, Richard, Frangi-Kultalahti, Jane, Pin, Anica, Vicari, Luisa, Moschovitis, Giorgio, Ehret, Georg, Gallet, Hervé, Guillermet, Elise, Lazeyras, Francois, Lovblad, Karl-Olof, Perret, Patrick, Tavel, Philippe, Teres, Cheryl, Shah, Dipen, Lauriers, Nathalie, Méan, Marie, Salzmann, Sandrine, Schläpfer, Jürg, Grêt, Andrea, Novak, Jan, Vitelli, Sandra, Stephan, Frank-Peter, Gallino, Augusto, Di Valentino, Marcello, Witassek, Fabienne, Schwenkglenks, Matthias, Würfel, Jens, Altermatt, Anna, Amann, Michael, Huber, Petra, Ruberte, Esther, Sinnecker, Tim, Zuber, Vanessa, Coslovsky, Michael, Benkert, Pascal, Dutilh, Gilles, Markovic, Milica, Simon, Patrick, Schmid, Ramun, Beer, Jürg H., Bonati, Leo H., Blum, Manuel R., Kastner, Peter, and Baguley, Fiona

Published
2021
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8. LB-456088-4 SAFETY AND EFFICACY OF A LEADLESS ULTRASOUND-BASED CARDIAC RESYNCHRONIZATION PACING SYSTEM IN HEART FAILURE – RESULTS FROM THE SOLVE-CRT STUDY

Author

Singh, Jagmeet P., primary, Rinaldi, Christopher A., additional, Sanders, Prashanthan, additional, Kubo, Spencer H., additional, James, Simon, additional, Niazi, Imran K., additional, Betts, Timothy R., additional, Butter, Christian, additional, Okabe, Toshimasa, additional, Latacha, Matthew P., additional, Cunnane, Ryan, additional, Aziz, Emad F., additional, Biffi, Mauro, additional, Zaidi, Amir M., additional, Alison, Jeffrey F., additional, Auricchio, Angelo, additional, Gold, Michael R., additional, Lindenfeld, JoAnn, additional, and Walsh, Mary N., additional

Published
2023
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9. CI-452767-4 NON-INVASIVE 3D ELECTRICAL ACTIVATION MAPPING TO PREDICT CRT RESPONSE: SITE OF LATEST LV ACTIVATION RELATIVE TO PACING SITE

Author

Parreira, Leonor, primary, Tsyganov, Alexey, additional, Artyukhina, Elena, additional, Vernooy, Kevin, additional, Tondo, Claudio, additional, Adragao, Pedro, additional, Ascione, Ciro, additional, Carmo, Pedro, additional, Carvalho, Maria, additional, Egger, Matthias, additional, Ferreira, António, additional, Ghossein, Mohammed A., additional, Holm, Magnus C., additional, Kalinin, Vitaly, additional, Malakhova, Maria, additional, Meine, Mathias, additional, Nunes, Sílvia, additional, Podolyak, Dmitry, additional, Revishvili, Amiran S., additional, Shapieva, Albina, additional, Stepanova, Vera, additional, van Stipdonk, Antonius, additional, Taymasova, Irina, additional, Wouters, Philippe, additional, Zubarev, Stepan, additional, Leyva, Francisco, additional, Auricchio, Angelo, additional, and Varma, Niraj, additional

Published
2023
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10. Activation time at left ventricular pacing site (QLV) relative to actual site of latest activation – implications for response to cardiac resynchronization therapy

Author

Varma, Niraj, primary, Parreira, Leonor, additional, Tsyganov, Alexey, additional, Artyukhina, Elena, additional, Vernooy, Kevin, additional, Tondo, Claudio, additional, Ascione, Ciro, additional, Carvalho, Salomé, additional, Egger, Matthias, additional, Holm, Magnus, additional, Shapieva, Albina, additional, van Stipdonk, Antonius, additional, Taymasova, Irina, additional, Zubarev, Stepan, additional, and Auricchio, Angelo, additional

Published
2023
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15. HP-574-03 NEW-ONSET BLEEDING AND SUBSEQUENT RISK OF CARDIOVASCULAR OUTCOMES IN ANTICOAGULATED PATIENTS WITH ATRIAL FIBRILLATION

Author

Meyre, Pascal, primary, Paladini, Rebecca E., additional, Hennings, Elisa, additional, Aeschbacher, Stefanie, additional, Reichlin, Tobias, additional, Rodondi, Nicolas, additional, Stauber, Annina, additional, Müller, Andreas, additional, Moschovitis, Giorgio, additional, Conte, Giulio, additional, Auricchio, Angelo, additional, Schwenkglenks, Matthias, additional, Kühne, Michael, additional, Osswald, Stefan, additional, and Conen, David, additional

Published
2022
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18. PO-06-043 FIRST RESULTS FROM CARDIAC RESYNCHRONIZATION THERAPY DELIVERY GUIDED BY NON-INVASIVE ELECTRICAL AND VENOUS ANATOMY ASSESSMENT (CRT-DRIVE) CLINICAL TRIAL

Author

Chmelevsky, Mikhail, Friedman, Daniel J., Lopez, Margarida Pujol, Mont, Lluis, Kollias, Georgios, Pürerfellner, Helmut, Özkartal, Tardu, Zubarev, Stepan, Budanova, Margarita, Khamzin, Svyatoslav, Dokuchaev, Arsenii, Bazhutina, Anastasia, Sinitca, Aleksandr, Rainer, Werner, and Auricchio, Angelo

Published
2024
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19. B-PO05-054 PACEMAKER DEPENDENCY AND OUTCOMES OF TRANVENOUS LEAD EXTRACTION - DATA FROM THE ELECTRA REGISTRY

Author

Leshem, Eran, primary, Zahavi, Guy, additional, Bongiorni, Maria Grazia, additional, Auricchio, Angelo, additional, Butter, Christian, additional, Dagres, Nikolaos, additional, DEHARO, Jean-Claude, additional, Rinaldi, Christopher A., additional, Maggioni, Aldo P., additional, Kutarski, Andrzej, additional, Kennergren, Charles E.H., additional, Laroche, Cecile, additional, Bogdan, Stefan, additional, Mortsell, David, additional, Calvi, Valeria, additional, Beinart, Roy, additional, Desiron, Quentin, additional, Mansourati, Jacques, additional, Glikson, Michael, additional, Lundqvist, Carina Blomström, additional, and Nof, Eyal, additional

Published
2021
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21. HRS/EHRA Expert Consensus on the Monitoring of Cardiovascular Implantable Electronic Devices (CIEDs): Description of Techniques, Indications, Personnel, Frequency and Ethical Considerations: Developed in partnership with the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA); and in collaboration with the American College of Cardiology (ACC), the American Heart Association (AHA), the European Society of Cardiology (ESC), the Heart Failure Association of ESC (HFA), and the Heart Failure Society of America (HFSA). Endorsed by the Heart Rhythm Society, the European Heart Rhythm Association (a registered branch of the ESC), the American College of Cardiology, the American Heart Association

Author

Wilkoff, Bruce L., Auricchio, Angelo, Brugada, Josep, Cowie, Martin, Ellenbogen, Kenneth A., Gillis, Anne M., Hayes, David L., Howlett, Jonathan G., Kautzner, Josef, Love, Charles J., Morgan, John M., Priori, Silvia G., Reynolds, Dwight W., Schoenfeld, Mark H., and Vardas, Panos E.

Published
2008
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22. Insulin-like growth factor-binding protein 7 and risk of congestive heart failure hospitalization in patients with atrial fibrillation

Author

Blum, Steffen, primary, Aeschbacher, Stefanie, additional, Meyre, Pascal, additional, Kühne, Michael, additional, Rodondi, Nicolas, additional, Beer, Jürg H., additional, Ammann, Peter, additional, Moschovitis, Giorgio, additional, Bonati, Leo H., additional, Blum, Manuel R., additional, Kastner, Peter, additional, Baguley, Fiona, additional, Sticherling, Christian, additional, Osswald, Stefan, additional, Conen, David, additional, Auberson, Chloé, additional, Blum, Steffen, additional, Bonati, Leo, additional, Ceylan, Selinda, additional, Doerpfeld, Simone, additional, Eken, Ceylan, additional, Girod, Marc, additional, Hämmerle, Peter, additional, Krisai, Philipp, additional, Meyer-Zürn, Christine, additional, Monsch, Andreas U., additional, Müller, Christian, additional, Springer, Anne, additional, Szucs, Thomas, additional, Voellmin, Gian, additional, Zwimpfer, Leon, additional, Aujesky, Drahomir, additional, Fischer, Urs, additional, Fuhrer, Juerg, additional, Roten, Laurent, additional, Jung, Simon, additional, Mattle, Heinrich, additional, Adam, Luise, additional, Aubert, Carole Elodie, additional, Feller, Martin, additional, Loewe, Axel, additional, Moutzouri, Elisavet, additional, Schneider, Claudio, additional, Flückiger, Tanja, additional, Groen, Cindy, additional, Ehrsam, Lukas, additional, Hellrigl, Sven, additional, Nuoffer, Alexandra, additional, Rakovic, Damiana, additional, Schwab, Nathalie, additional, Wenger, Rylana, additional, Beynon, Christopher, additional, Dillier, Roger, additional, Deubelbeiss, Michèle, additional, Eberli, Franz, additional, Franzini, Christine, additional, Juchli, Isabel, additional, Liedtke, Claudia, additional, Nadler, Jacqueline, additional, Obst, Thayze, additional, Roth, Jasmin, additional, Schlomowitsch, Fiona, additional, Schneider, Xiaoye, additional, Studerus, Katrin, additional, Tynan, Noreen, additional, Weishaupt, Dominik, additional, Müller, Andreas, additional, Fontana, Simone, additional, Kuest, Silke, additional, Scheuch, Karin, additional, Hischier, Denise, additional, Bonetti, Nicole, additional, Grau, Alexandra, additional, Villinger, Jonas, additional, Laube, Eva, additional, Baumgartner, Philipp, additional, Filipovic, Mark, additional, Frick, Marcel, additional, Montrasio, Giulia, additional, Leuenberger, Stefanie, additional, Rutz, Franziska, additional, Beer, Jürg-Hans, additional, Auricchio, Angelo, additional, Anesini, Adriana, additional, Camporini, Cristina, additional, Conte, Giulio, additional, Caputo, Maria Luce, additional, Regoli, Francois, additional, Moccetti, Tiziano, additional, Brenner, Roman, additional, Altmann, David, additional, Gemperle, Michaela, additional, Firmann, Mathieu, additional, Foucras, Sandrine, additional, Rime, Martine, additional, Hayoz, Daniel, additional, Berte, Benjamin, additional, Justi, Virgina, additional, Kellner-Weldon, Frauke, additional, Mehmann, Brigitta, additional, Meier, Sonja, additional, Roth, Myriam, additional, Ruckli-Kaeppeli, Andrea, additional, Russi, Ian, additional, Schmidt, Kai, additional, Young, Mabelle, additional, Zbinden, Melanie, additional, Kobza, Richard, additional, Frangi-Kultalahti, Jane, additional, Pin, Anica, additional, Vicari, Luisa, additional, Ehret, Georg, additional, Gallet, Hervé, additional, Guillermet, Elise, additional, Lazeyras, Francois, additional, Lovblad, Karl-Olof, additional, Perret, Patrick, additional, Tavel, Philippe, additional, Teres, Cheryl, additional, Shah, Dipen, additional, Lauriers, Nathalie, additional, Méan, Marie, additional, Salzmann, Sandrine, additional, Schläpfer, Jürg, additional, Grêt, Andrea, additional, Novak, Jan, additional, Vitelli, Sandra, additional, Stephan, Frank-Peter, additional, Gallino, Augusto, additional, Di Valentino, Marcello, additional, Witassek, Fabienne, additional, Schwenkglenks, Matthias, additional, Würfel, Jens, additional, Altermatt, Anna, additional, Amann, Michael, additional, Huber, Petra, additional, Ruberte, Esther, additional, Sinnecker, Tim, additional, Zuber, Vanessa, additional, Coslovsky, Michael, additional, Benkert, Pascal, additional, Dutilh, Gilles, additional, Markovic, Milica, additional, Simon, Patrick, additional, and Schmid, Ramun, additional

Published
2021
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26. Defibrillator shocks and their effect on objective and subjective patient outcomes: Results of the PainFree SST clinical trial

Author

Sears, Samuel F., primary, Rosman, Lindsey, additional, Sasaki, Shingo, additional, Kondo, Yusuke, additional, Sterns, Laurence D., additional, Schloss, Edward J., additional, Kurita, Takashi, additional, Meijer, Albert, additional, Raijmakers, Judith, additional, Gerritse, Bart, additional, and Auricchio, Angelo, additional

Published
2018
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28. Low inappropriate shock rates in patients with single- and dual/triple-chamber implantable cardioverter-defibrillators using a novel suite of detection algorithms: PainFree SST trial primary results

Author

Auricchio, Angelo, primary, Schloss, Edward J., additional, Kurita, Takashi, additional, Meijer, Albert, additional, Gerritse, Bart, additional, Zweibel, Steven, additional, AlSmadi, Faisal M., additional, Leng, Charles T., additional, and Sterns, Laurence D., additional

Published
2015
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29. Clinical utility of routine use of continuous transesophageal echocardiography monitoring during transvenous lead extraction procedure

Author

Regoli, François, primary, Caputo, Maria, additional, Conte, Giulio, additional, Faletra, Francesco F., additional, Moccetti, Tiziano, additional, Pasotti, Elena, additional, Cassina, Tiziano, additional, Casso, Gabriele, additional, Schlotterbeck, Hervé, additional, Engeler, Albin, additional, and Auricchio, Angelo, additional

Published
2015
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30. Extended detection time to reduce shocks is safe in secondary prevention patients: The secondary prevention substudy of PainFree SST.

Author

Sterns, Laurence D., Meine, Mathias, Kurita, Takashi, Meijer, Albert, Auricchio, Angelo, Ando, Kenji, Leng, Charles T., Okumura, Ken, Sapp, John L., Brown, Mark L., Lexcen, Daniel R., Gerritse, Bart, and Schloss, Edward J.

Abstract

Background: Prolonged ventricular fibrillation (VF) detection has been shown to reduce implantable cardioverter-defibrillator (ICD) therapies and improve prognosis in primary prevention ICD patients. Data in secondary prevention patients are limited.Objective: The PainFree SST secondary prevention study is the largest trial of secondary prevention patients randomized between standard and prolonged detection to assess the safety of this strategy in these patients.Methods: A total of 705 secondary prevention patients implanted with an ICD in the PainFree SST trial were enrolled in this substudy; 353 patients were randomized to VF detection of 18/24 intervals and 352 patients to 30/40. All other VF parameters were standardized by protocol.Results: The 1-year arrhythmic syncope-free rates in the standard and prolonged groups were 97.7% vs 96.9%, respectively, (P = .0034 for noninferiority). Freedom from all-cause syncope was 96% in both arms (P = .0013 for noninferiority). There was no difference in the time to first appropriate or inappropriate VF therapy. However, the rates of treated VF episodes were lower in the prolonged arm (1.48 per patient per year vs 0.44 per patient per year, P = .0001). A trend toward lower mortality in the prolonged group was not statistically different (5.6% 1 year, 12% 2 years vs 3.8% 1 year, 7.7% 2 years, adjusted hazard ratio = 0.60, P = .061).Conclusion: This large prospective randomized study shows that prolonged detection can safely be programmed in secondary prevention ICD patients with new or existing devices. This programming strategy decreases the rate of treated events and is not associated with an increased risk of syncope or mortality. [ABSTRACT FROM AUTHOR]

Published
2016
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31. 2012 EHRA/HRS expert consensus statement on cardiac resynchronization therapy in heart failure: implant and follow-up recommendations and management

Author

Daubert, Jean-Claude, primary, Saxon, Leslie, additional, Adamson, Philip B., additional, Auricchio, Angelo, additional, Berger, Ronald D., additional, Beshai, John F., additional, Breithard, Ole, additional, Brignole, Michele, additional, Cleland, John, additional, DeLurgio, David B., additional, Dickstein, Kenneth, additional, Exner, Derek V., additional, Gold, Michael, additional, Grimm, Richard A., additional, Hayes, David L., additional, Israel, Carsten, additional, Leclercq, Christophe, additional, Linde, Cecilia, additional, Lindenfeld, JoAnn, additional, Merkely, Bela, additional, Mont, Lluis, additional, Murgatroyd, Francis, additional, Prinzen, Frits, additional, Saba, Samir F., additional, Shinbane, Jerold S., additional, Singh, Jagmeet, additional, Tang, Anthony S., additional, Vardas, Panos E., additional, Wilkoff, Bruce L., additional, and Zamorano, Jose Luis, additional

Published
2012
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40. Insulin-like growth factor-binding protein 7 and risk of congestive heart failure hospitalization in patients with atrial fibrillation

Author

Steffen Blum, Stefanie Aeschbacher, Pascal Meyre, Michael Kühne, Nicolas Rodondi, Jürg H. Beer, Peter Ammann, Giorgio Moschovitis, Leo H. Bonati, Manuel R. Blum, Peter Kastner, Fiona Baguley, Christian Sticherling, Stefan Osswald, David Conen, Chloé Auberson, Leo Bonati, Selinda Ceylan, Simone Doerpfeld, Ceylan Eken, Marc Girod, Peter Hämmerle, Philipp Krisai, Christine Meyer-Zürn, Andreas U. Monsch, Christian Müller, Anne Springer, Thomas Szucs, Gian Voellmin, Leon Zwimpfer, Drahomir Aujesky, Urs Fischer, Juerg Fuhrer, Laurent Roten, Simon Jung, Heinrich Mattle, Luise Adam, Carole Elodie Aubert, Martin Feller, Axel Loewe, Elisavet Moutzouri, Claudio Schneider, Tanja Flückiger, Cindy Groen, Lukas Ehrsam, Sven Hellrigl, Alexandra Nuoffer, Damiana Rakovic, Nathalie Schwab, Rylana Wenger, Christopher Beynon, Roger Dillier, Michèle Deubelbeiss, Franz Eberli, Christine Franzini, Isabel Juchli, Claudia Liedtke, Jacqueline Nadler, Thayze Obst, Jasmin Roth, Fiona Schlomowitsch, Xiaoye Schneider, Katrin Studerus, Noreen Tynan, Dominik Weishaupt, Andreas Müller, Simone Fontana, Silke Kuest, Karin Scheuch, Denise Hischier, Nicole Bonetti, Alexandra Grau, Jonas Villinger, Eva Laube, Philipp Baumgartner, Mark Filipovic, Marcel Frick, Giulia Montrasio, Stefanie Leuenberger, Franziska Rutz, Jürg-Hans Beer, Angelo Auricchio, Adriana Anesini, Cristina Camporini, Giulio Conte, Maria Luce Caputo, Francois Regoli, Tiziano Moccetti, Roman Brenner, David Altmann, Michaela Gemperle, Mathieu Firmann, Sandrine Foucras, Martine Rime, Daniel Hayoz, Benjamin Berte, Virgina Justi, Frauke Kellner-Weldon, Brigitta Mehmann, Sonja Meier, Myriam Roth, Andrea Ruckli-Kaeppeli, Ian Russi, Kai Schmidt, Mabelle Young, Melanie Zbinden, Richard Kobza, Jane Frangi-Kultalahti, Anica Pin, Luisa Vicari, Georg Ehret, Hervé Gallet, Elise Guillermet, Francois Lazeyras, Karl-Olof Lovblad, Patrick Perret, Philippe Tavel, Cheryl Teres, Dipen Shah, Nathalie Lauriers, Marie Méan, Sandrine Salzmann, Jürg Schläpfer, Andrea Grêt, Jan Novak, Sandra Vitelli, Frank-Peter Stephan, Augusto Gallino, Marcello Di Valentino, Fabienne Witassek, Matthias Schwenkglenks, Jens Würfel, Anna Altermatt, Michael Amann, Petra Huber, Esther Ruberte, Tim Sinnecker, Vanessa Zuber, Michael Coslovsky, Pascal Benkert, Gilles Dutilh, Milica Markovic, Patrick Simon, Ramun Schmid, Clinical sciences, Auberson, Chloé, Bonati, Leo, Ceylan, Selinda, Doerpfeld, Simone, Eken, Ceylan, Girod, Marc, Hämmerle, Peter, Krisai, Philipp, Meyer-Zürn, Christine, Monsch, Andreas U., Müller, Christian, Springer, Anne, Szucs, Thomas, Voellmin, Gian, Zwimpfer, Leon, Aujesky, Drahomir, Fischer, Urs, Fuhrer, Juerg, Roten, Laurent, Jung, Simon, Mattle, Heinrich, Adam, Luise, Aubert, Carole Elodie, Feller, Martin, Loewe, Axel, Moutzouri, Elisavet, Schneider, Claudio, Flückiger, Tanja, Groen, Cindy, Ehrsam, Lukas, Hellrigl, Sven, Nuoffer, Alexandra, Rakovic, Damiana, Schwab, Nathalie, Wenger, Rylana, Beynon, Christopher, Dillier, Roger, Deubelbeiss, Michèle, Eberli, Franz, Franzini, Christine, Juchli, Isabel, Liedtke, Claudia, Nadler, Jacqueline, Obst, Thayze, Roth, Jasmin, Schlomowitsch, Fiona, Schneider, Xiaoye, Studerus, Katrin, Tynan, Noreen, Weishaupt, Dominik, Müller, Andreas, Fontana, Simone, Kuest, Silke, Scheuch, Karin, Hischier, Denise, Bonetti, Nicole, Grau, Alexandra, Villinger, Jonas, Laube, Eva, Baumgartner, Philipp, Filipovic, Mark, Frick, Marcel, Montrasio, Giulia, Leuenberger, Stefanie, Rutz, Franziska, Auricchio, Angelo, Anesini, Adriana, Camporini, Cristina, Conte, Giulio, Caputo, Maria Luce, Regoli, Francois, Moccetti, Tiziano, Brenner, Roman, Altmann, David, Gemperle, Michaela, Firmann, Mathieu, Foucras, Sandrine, Rime, Martine, Hayoz, Daniel, Berte, Benjamin, Justi, Virgina, Kellner-Weldon, Frauke, Mehmann, Brigitta, Meier, Sonja, Roth, Myriam, Ruckli-Kaeppeli, Andrea, Russi, Ian, Schmidt, Kai, Young, Mabelle, Zbinden, Melanie, Kobza, Richard, Frangi-Kultalahti, Jane, Pin, Anica, Vicari, Luisa, Ehret, Georg Benedikt, Gallet, Hervé, Guillermet, Elise, Lazeyras, François, Lövblad, Karl-Olof, Perret, Patrick, Tavel, Philippe, Teres Castillo, Cheryl, Shah, Dipen, Lauriers, Nathalie, Méan, Marie, Salzmann, Sandrine, Schläpfer, Jürg, Grêt, Andrea, Novak, Jan, Vitelli, Sandra, Stephan, Frank-Peter, Gallino, Augusto, Di Valentino, Marcello, Witassek, Fabienne, Schwenkglenks, Matthias, Würfel, Jens, Altermatt, Anna, Amann, Michael, Huber, Petra, Ruberte, Esther, Sinnecker, Tim, Zuber, Vanessa, Coslovsky, Michael, Benkert, Pascal, Dutilh, Gilles, Markovic, Milica, Simon, Patrick, and Schmid, Ramun

Subjects
Male, medicine.medical_specialty, medicine.drug_class, Epidemiology, Heart failure, 030204 cardiovascular system & hematology, ddc:616.0757, 03 medical and health sciences, 0302 clinical medicine, Insulin-Like Growth Factor Binding Proteins/blood, Physiology (medical), Internal medicine, Atrial Fibrillation, Clinical endpoint, Natriuretic peptide, medicine, Heart Failure/blood, Humans, 030212 general & internal medicine, cardiovascular diseases, Hospitalization/statistics & numerical data, Aged, Retrospective Studies, ddc:616, Heart Failure, Proportional hazards model, business.industry, Insulin-like growth factor-binding protein 7, Hazard ratio, Atrial fibrillation, Middle Aged, medicine.disease, Prognosis, Confidence interval, Hospitalization, Insulin-Like Growth Factor Binding Proteins, Atrial Fibrillation/blood, Cardiology, Disease Progression, Female, business, Cardiology and Cardiovascular Medicine, Biomarkers/blood, Biomarkers, Cohort study, Follow-Up Studies
Abstract

BACKGROUND: The occurrence of congestive heart failure (CHF) hospitalization among patients with atrial fibrillation (AF) is a poor prognostic marker. OBJECTIVE: The purpose of this study was to assess whether insulin-like growth factor-binding protein 7 (IGFBP-7), a marker of myocardial damage, identifies AF patients at high risk for this complication. METHODS: We analyzed 2 prospective multicenter observational cohort studies that included 3691 AF patients. Levels of IGFBP-7 and N-terminal pro-brain natriuretic peptide (NT-proBNP) were measured from frozen plasma samples at baseline. The primary endpoint was hospitalization for CHF. Multivariable adjusted Cox regression analyses were constructed. RESULTS: Mean patient age was 69 ± 12 years, 1028 (28%) were female, and 879 (24%) had a history of CHF. The incidence per 1000 patient-years across increasing IGFBP-7 quartiles was 7, 10, 32, and 85. The corresponding multivariable adjusted hazard ratios (aHRs) (95% confidence interval [CI]) were 1.0, 1.05 (0.63-1.77), 2.38 (1.50-3.79), and 4.37 (2.72-7.04) (P for trend

Published
2020

41. In vivo electromechanical assessment of heart failure patients with prolonged QRS duration

Author

Rolf Krause, Romina Murzilli, Tammo Delhaas, Frits W. Prinzen, Catherine Klersy, Joost Lumens, Wilco Kroon, Tiziano Moccetti, Mark Potse, Angelo Auricchio, Daniel Suerder, François Regoli, Promovendi CD, Biomedische Technologie, Fysiologie, RS: CARIM - R2 - Cardiac function and failure, RS: MHeNs - R3 - Neuroscience, University of Zurich, and Auricchio, Angelo

Subjects
medicine.medical_specialty, Magnetic Resonance Spectroscopy, medicine.medical_treatment, Heart Ventricles, Cardiac resynchronization therapy, 610 Medicine & health, 11171 Cardiocentro Ticino, 2705 Cardiology and Cardiovascular Medicine, Contractility, QRS complex, Electrocardiography, 2737 Physiology (medical), Interquartile range, Physiology (medical), Internal medicine, medicine, Humans, Computer Simulation, Aged, Heart Failure, Cardiac cycle, business.industry, Left bundle branch block, Depolarization, medicine.disease, Myocardial Contraction, Heart failure, Cardiology, Cardiology and Cardiovascular Medicine, business
Abstract

Combined measurement of electrical activation and mechanical dyssynchrony in heart failure (HF) patients is scarce but may contain important mechanistic and diagnostic clues.The purpose of this study was to characterize the electromechanical (EM) coupling in HF patients with prolonged QRS duration.Ten patients with QRS width120 ms underwent left ventricular (LV) electroanatomic contact mapping using the Noga® XP system (Biosense Webster). Recorded voltages during the cardiac cycle were converted to maps of depolarization time (TD). Electrode positions were tracked and converted into maps of time-to-peak shortening (TPS) using custom-made deformation analysis software. Correlation analysis was performed between the 2 maps to quantify EM coupling. Simulations with the CircAdapt cardiovascular system model were performed to mechanistically unravel the observed relation between TD and TPS.The delay between earliest LV electrical activation and peak shortening differed considerably between patients (TPSmin-TDmin = 360 ± 73 ms). On average, total mechanical dyssynchrony exceeded total electrical activation (ΔTPS = 177 ± 47 ms vs ΔTD = 93 ± 24 ms, P.001), but a large interpatient variability was observed. The TD and TPS maps correlated strongly in all patients (median R = 0.87, P.001). These correlations were similar for regions with unipolar voltages above and below 6mV (Mann-Whitney U test, P = .93). Computer simulations revealed that increased passive myocardial stiffness decreases ΔTPS relative to ΔTD and that lower contractility predominantly increases TPSmin-TDmin.EM coupling in HF patients is maintained, but the relationship between TD and TPS differs strongly between patients. Intra-individual and inter-individual differences may be explained by local and global differences in passive and contractile myocardial properties.

Published
2015

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