1. Increased prevalence of cerebral microbleeds in patients with low left ventricular systolic function
- Author
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Koichi Sohmiya, Yusuke Nishida, Kenichiro Yamamura, Masaaki Hoshiga, Yumiko Kanzaki, Takahide Ito, Tomohiko Watanabe, Yohei Yamauchi, and Tsuyoshi Komori
- Subjects
Cardiac function curve ,Male ,medicine.medical_specialty ,medicine.drug_class ,Systole ,030204 cardiovascular system & hematology ,Risk Assessment ,Ventricular Function, Left ,03 medical and health sciences ,Ventricular Dysfunction, Left ,0302 clinical medicine ,Japan ,Risk Factors ,Internal medicine ,medicine ,Prevalence ,Humans ,030212 general & internal medicine ,Aged ,Cerebral Hemorrhage ,Retrospective Studies ,Aged, 80 and over ,Ejection fraction ,medicine.diagnostic_test ,business.industry ,Anticoagulant ,Age Factors ,Magnetic resonance imaging ,Retrospective cohort study ,Stroke Volume ,Odds ratio ,Middle Aged ,Magnetic Resonance Imaging ,Confidence interval ,Cardiac surgery ,Echocardiography ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,business - Abstract
Gradient-echo T2-star (T2*)-weighted magnetic resonance imaging (MRI) is a sensitive method to detect cerebral microbleeds (CMBs). The presence of CMBs was reported to be a marker of future cardiovascular mortality and is associated with various cardiovascular risk factors, use of antithrombotic drugs, and cognitive dysfunction. However, the relationship between cardiac function and CMBs remains unclear. We investigated the association between cardiac function and presence of CMBs in patients with cardiovascular diseases. This single-center retrospective study included a total of 424 participants (mean age 70 ± 12 years; men 286 (67%); mean left ventricular ejection fraction (LVEF) 61% ± 12%] who underwent echocardiography and brain T2*-weighted MRI within 1 month without neurologic abnormality. CMBs were found in 118 (28%) patients. There was no significant relationship between CMBs and anticoagulant or antiplatelet therapy. LVEF was significantly lower in patients with CMBs than in those without CMBs (59% ± 13% vs. 62% ± 11%, P
- Published
- 2019