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Your search keyword '"Pieper, Petronella G."' showing total 16 results
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16 results on '"Pieper, Petronella G."'

9. Bleeding and thrombotic risk in pregnant women with Fontan physiology

Author

Girnius, Andrea, primary, Zentner, Dominica, additional, Valente, Anne Marie, additional, Pieper, Petronella G, additional, Economy, Katherine E, additional, Ladouceur, Magalie, additional, Roos-Hesselink, Jolien W, additional, Warshak, Carri, additional, Partington, Sara L, additional, Gao, Zhiqian, additional, Ollberding, Nicholas, additional, Faust, Michelle, additional, Girnius, Saulius, additional, Kaemmerer, Harald, additional, Nagdyman, Nicole, additional, Cohen, Scott, additional, Canobbio, Mary, additional, Akagi, Teiji, additional, Grewal, Jasmine, additional, Bradley, Elisa, additional, Buber, Yonathan, additional, Palumbo, Joseph, additional, Walker, Niki, additional, Aboulhosn, Jamil, additional, Oechslin, Erwin, additional, Baumgartner, Helmut, additional, Kurdi, Wesam, additional, Book, Wendy M, additional, Mulder, Barbara J M, additional, and Veldtman, Gruschen R, additional

Published
2020
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11. The emerging burden of hospital admissions of adults with congenital heart disease

Author

Vergheugt, Carianne L., Uiterwaal, Cuno S.P.M., van der Velde, Enno T., Meijboom, Folkert J., Pieper, Petronella G., Sieswerda, Gertjan T.J., Plokker, Herbert W.M., Grobbee, Diedrick E., and Mulder, Barbara J.M.

Subjects
Congenital heart disease -- Statistics, Congenital heart disease -- Demographic aspects, Congenital heart disease -- Research, Hospitals -- Admission and discharge, Hospitals -- Statistics, Hospitals -- Demographic aspects, Hospitals -- Research, Health
Published
2010

12. Bleeding and thrombotic risk in pregnant women with Fontan physiology.

Author

Girnius, Andrea, Zentner, Dominica, Valente, Anne Marie, Pieper, Petronella G., Economy, Katherine E., Ladouceur, Magalie, Roos-Hesselink, Jolien W., Warshak, Carri, Partington, Sara L., Zhiqian Gao, Ollberding, Nicholas, Faust, Michelle, Girnius, Saulius, Kaemmerer, Harald, Nagdyman, Nicole, Cohen, Scott, Canobbio, Mary, Teiji Akagi, Grewal, Jasmine, and Bradley, Elisa

Subjects
PHYSIOLOGY of women, PREGNANT women, MECHANICAL hearts, BUDD-Chiari syndrome, PREMATURE rupture of fetal membranes, ATRIAL arrhythmias, DENTISTRY
Abstract

Background/objectives: Pregnancy may potentiate the inherent hypercoagulability of the Fontan circulation, thereby amplifying adverse events. This study sought to evaluate thrombosis and bleeding risk in pregnant women with a Fontan.Methods: We performed a retrospective observational cohort study across 13 international centres and recorded data on thrombotic and bleeding events, antithrombotic therapies and pre-pregnancy thrombotic risk factors.Results: We analysed 84 women with Fontan physiology undergoing 108 pregnancies, average gestation 33±5 weeks. The most common antithrombotic therapy in pregnancy was aspirin (ASA, 47 pregnancies (43.5%)). Heparin (unfractionated (UFH) or low molecular weight (LMWH)) was prescribed in 32 pregnancies (30%) and vitamin K antagonist (VKA) in 10 pregnancies (9%). Three pregnancies were complicated by thrombotic events (2.8%). Thirty-eight pregnancies (35%) were complicated by bleeding, of which 5 (13%) were severe. Most bleeds were obstetric, occurring antepartum (45%) and postpartum (42%). The use of therapeutic heparin (OR 15.6, 95% CI 1.88 to 129, p=0.006), VKA (OR 11.7, 95% CI 1.06 to 130, p=0.032) or any combination of anticoagulation medication (OR 13.0, 95% CI 1.13 to 150, p=0.032) were significantly associated with bleeding events, while ASA (OR 5.41, 95% CI 0.73 to 40.4, p=0.067) and prophylactic heparin were not (OR 4.68, 95% CI 0.488 to 44.9, p=0.096).Conclusions: Current antithrombotic strategies appear effective at attenuating thrombotic risk in pregnant women with a Fontan. However, this comes with high (>30%) bleeding risk, of which 13% are life threatening. Achieving haemostatic balance is challenging in pregnant women with a Fontan, necessitating individualised risk-adjusted counselling and therapeutic approaches that are monitored during the course of pregnancy. [ABSTRACT FROM AUTHOR]

Published
2021
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14. Aortic valve prosthesis–patient mismatch and exercise capacity in adult patients with congenital heart disease

Author

van Slooten, Ymkje J, primary, van Melle, Joost P, additional, Freling, Hendrik G, additional, Bouma, Berto J, additional, van Dijk, Arie PJ, additional, Jongbloed, Monique RM, additional, Post, Martijn C, additional, Sieswerda, Gertjan T, additional, Huis in ‘t Veld, Anna, additional, Ebels, Tjark, additional, Voors, Adriaan A, additional, and Pieper, Petronella G, additional

Published
2015
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15. Is a planned caesarean section in women with cardiac disease beneficial?

Author

Ruys, Titia P E, primary, Roos-Hesselink, Jolien W, additional, Pijuan-Domènech, Antonia, additional, Vasario, Elena, additional, Gaisin, Ilshat R, additional, Iung, Bernard, additional, Freeman, Leisa J, additional, Gordon, Elaine P, additional, Pieper, Petronella G, additional, Hall, Roger, additional, Boersma, Eric, additional, and Johnson, Mark R, additional

Published
2014
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16. Heart failure in pregnant women with cardiac disease: data from the ROPAC

Author

Ruys, Titia P E, primary, Roos-Hesselink, Jolien W, additional, Hall, Roger, additional, Subirana-Domènech, Maria T, additional, Grando-Ting, Jennifer, additional, Estensen, Mette, additional, Crepaz, Roberto, additional, Fesslova, Vlasta, additional, Gurvitz, Michelle, additional, De Backer, Julie, additional, Johnson, Mark R, additional, and Pieper, Petronella G, additional

Published
2013
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