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12. Oral presentations. (Abstracts)

Author

Ali, SKM, duPlessis, J., Godman, M.J., Das, P., Rimington, H., Chambers, J., Jiang, B., Gale, C., and Godfred, K.

Subjects
Aortic valve -- Statistics -- Evaluation -- Measurement -- Physiological aspects, Heart function tests -- Evaluation -- Physiological aspects -- Statistics -- Measurement, Heart muscle -- Physiological aspects -- Statistics -- Measurement, Heart ventricle, Left -- Measurement -- Statistics -- Physiological aspects, Aortic valve stenosis -- Physiological aspects -- Measurement -- Statistics, Health, Statistics, Evaluation, Physiological aspects, Measurement
Abstract

1

Published
2002

14. 026 TRENDS IN IN-HOSPITAL TREATMENTS, INCLUDING REVASCULARISATION, FOLLOWING ACUTE MYOCARDIAL INFARCTION, 2003–2010: A MULTI-LEVEL AND RELATIVE SURVIVAL ANALYSIS FOR THE NATIONAL INSTITUTE FOR CARDIOVASCULAR OUTCOMES RESEARCH (NICOR)

Author

Gale, C P, primary, Allan, V, additional, Cattle, B A, additional, Hall, A S, additional, West, R M, additional, Timmis, A, additional, Gray, H H, additional, Deanfield, J E, additional, Fox, K A A, additional, and Feltbower, R, additional

Published
2013
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18. 010 QUANTIFYING THE ASSOCIATION BETWEEN MORTALITY AND CHANGE IN ACE INHIBITOR AND β-BLOCKER DOSE IN PATIENTS WITH CHRONIC HEART FAILURE: A PROSPECTIVE COHORT STUDY

Author

Adams, B, primary, Cubbon, R M, additional, Witte, K K, additional, Rajwani, A, additional, Kearney, L C, additional, Gierula, J, additional, Sapsford, R J, additional, Mercer, B N, additional, Gatenby, V K, additional, Gale, C P, additional, Gilthorpe, M S, additional, and Kearney, M T, additional

Published
2013
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28. Predictors of in-hospital mortality for patients admitted with ST-elevation myocardial infarction: real-world study using the Myocardial Infarction National Audit Project (MINAP) database.

Author

Gale, C. P., Manda, S. O. M., Batin, P. D., Weston, C. F., Birkhead, J. S., and Hall, A. S.

Subjects
*MYOCARDIAL infarction, *THROMBOLYTIC therapy, *PATIENTS, *MORTALITY, *BLOOD pressure
Abstract

Objective: Although early thrombolysis reduces the risk of death in STEMI patients, mortality remains high. We evaluated factors predicting inpatient mortality for patients with STEMI in a "real-world" population. Design: Analysis of the Myocardial Infarction National Audit Project (MINAP) database using multivariate logistic regression and area under the receiver operating curve analysis. Setting: All acute hospitals in England and Wales. Patients: 34 722 patients with STEMI from 1 January 2003 to 31 March 2005. Results: Inpatient mortality was 10.6%. The highest odds ratios for inpatient survival were aspirin therapy given acutely and out-of-hospital thrombolysis, independently associated with a mortality risk reduction of over half. A 10-year increase in age doubled inpatient mortality risk, whereas cerebrovascular disease increased it by 1.7. The risk model comprised 14 predictors of mortality, C index = 0.82 (95% Cl 0.82 to 0.83, p<0.001). A simple model comprising age, systolic blood pressure (SBP) and heart rate (HR) offered a C index of 0.80 (0.79 to 0.80, p<0.001). Conclusion: The strongest predictors of in-hospital survival for STEMI were aspirin therapy given acutely and out-of-hospital thrombolysis, Previous STEMI models have focused on age, SBP and HR We have confirmed the importance of these predictors in the discrimination of death after STEMI, but also demonstrated that other potentially modifiable variables impact upon the prediction of short-term mortality. [ABSTRACT FROM AUTHOR]

Published
2008
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